Breast Cancer

• CLINICAL_TRIALS trial_result · 2023-03-01
  Clinical Trial Update: Letrozole Plus Metronomic Capecitabine as First-line Treatment for Patients With Recurrent or Metastatic Breast Cancer [Phase 2]

  Phase 2 trial evaluating letrozole plus metronomic capecitabine as first-line therapy for recurrent or metastatic breast cancer.

• CLINICAL_TRIALS trial_result · 2023-02-28
  Clinical Trial Update: Oral Vinorelbine and Capecitabine in Advanced HER2-negative Breast Cancer [Phase 2]

  Phase 2 trial exploring oral vinorelbine plus capecitabine in advanced HER2-negative breast cancer.

• CLINICAL_TRIALS trial_result · 2023-02-28
  Clinical Trial Update: Chidamide in Combination With Vincristine Metronomic Chemotherapy for Advanced Triple-negative Breast Cancer [Phase 1, Phase 2]

  A clinical trial update for chidamide in combination with vincristine metronomic chemotherapy in advanced triple-negative breast cancer, cur…

• CLINICAL_TRIALS trial_result · 2023-02-28
  Clinical Trial Update: Arginase-1 Peptide Vaccine in Patients With Metastatic Solid Tumors [Phase 1]

  Phase 1 trial update on an arginase-1 peptide vaccine in patients with metastatic solid tumors, including non-small cell lung cancer and uro…

• CLINICAL_TRIALS trial_result · 2023-02-27
  Clinical Trial Update: Clinical Trial to Assess Efficacy and Safety of NNG-TMAB (Trastuzumab) on Recurrent or Metastatic Breast Cancer Patients [Phase 3]

  Phase 3 trial update evaluating trastuzumab (NNG-TMAB) for recurrent or metastatic breast cancer has completed.

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• CLINICAL_TRIALS trial_result · 2023-02-23
  Clinical Trial Update: Injection Regimen Trial of PEG-rhG-CSF During Breast Cancer Chemotherapy [Phase 2]

  Phase 2 trial update for an injection regimen of PEG-rhG-CSF during chemotherapy in breast cancer patients.

• CLINICAL_TRIALS trial_result · 2023-02-23
  Clinical Trial Update: Cardioprotective Effects of Nebivolol Versus Placebo in Patients Undergoing Chemotherapy With Anthracyclines [Phase 3]

  Phase 3 trial evaluating nebivolol for cardioprotective effects during anthracycline chemotherapy in cancer patients.

• CLINICAL_TRIALS trial_result · 2023-02-22
  Clinical Trial Update: Transdermal or Oral Telapristone Acetate in Treating Patients Undergoing Mastectomy [Phase 2]

  Phase 2 clinical trial evaluating transdermal or oral telapristone acetate in patients undergoing mastectomy; trial completed with results p…

• CLINICAL_TRIALS trial_result · 2023-02-22
  Clinical Trial Update: Clinical Application of Dual Sentinel Lymph Node Staining Method in Breast Cancer Patients [Phase 2]

  Phase 2 clinical trial update on dual sentinel lymph node staining in breast cancer patients has completed.

• CLINICAL_TRIALS trial_result · 2023-02-22
  Clinical Trial Update: Dedicated Breast PET/MRI in Evaluation of Extent of Disease in Women With Newly Diagnosed Breast Cancer [NA]

  A clinical trial evaluating dedicated breast PET/MRI for assessing disease extent in women with newly diagnosed breast cancer has been termi…

• CLINICAL_TRIALS trial_result · 2023-02-21
  Clinical Trial Update: Serial FES PET/CT to Measure Hormone Expression in Patients Undergoing Endocrine Targeted Therapy [Phase 2]

  Phase 2 clinical trial update describing the use of serial FES PET/CT imaging to assess estrogen receptor expression in patients with estrog…

• CLINICAL_TRIALS trial_result · 2023-02-21
  Clinical Trial Update: Different Durations of Adjuvant Anastrozole Therapy After 2 to 3 Years Tamoxifen Therapy in Breast Cancer [Phase 3]

  A Phase 3 trial evaluating different durations of adjuvant anastrozole therapy after 2 to 3 years of tamoxifen in breast cancer patients.

• CLINICAL_TRIALS trial_result · 2023-02-21
  Clinical Trial Update: Dalpiciclib in Combination With Exemestane and Trastuzumab Plus Pyrotinib in Early Triple Positive Breast Cancer [Phase 2]

  Phase 2 trial exploring dalpiciclib in combination with exemestane, trastuzumab, and pyrotinib for early triple-positive breast cancer (ER+,…

• CLINICAL_TRIALS trial_result · 2023-02-21
  Clinical Trial Update: Phase II Trial of Talazoparib in BRCA1/2 Wild-type HER2-negative Breast Cancer and Other Solid Tumors [Phase 2]

  Phase II trial update of talazoparib in BRCA1/2 wild-type, HER2-negative breast cancer and other solid tumors has completed with results pos…

• CLINICAL_TRIALS research · 2023-02-21
  Clinical Trial Update: A Prospective, Phase II Trial Using ctDNA to Initiate Post-operation Boost Therapy After Adjuvant Chemotherapy in TNBC [Phase 2, Phase 3]

  A prospective Phase II trial using circulating tumor DNA to guide post-operation boost therapy after adjuvant chemotherapy in triple-negativ…

• CLINICAL_TRIALS trial_result · 2023-02-21
  Clinical Trial Update: Clinical Study of Pyrotinib in Neoadjuvant Therapy of HR-positive and HER2-positive Breast Cancer [Phase 2]

  Phase 2 clinical trial update for pyrotinib in neoadjuvant therapy for HR-positive and HER2-positive breast cancer.

• CLINICAL_TRIALS trial_result · 2023-02-16
  Clinical Trial Update: A Two-Arm Study to Evaluate the Pharmacokinetics, Efficacy, and Safety of Subcutaneous Administration of the Fixed-Dose Combination of Pertuzumab and Trastuzumab in Combination With Chemotherapy in Chinese Participants With HER2-Positive Early Breast Cancer [Phase 3]

  Phase 3 trial evaluating pharmacokinetics, efficacy, and safety of a subcutaneous fixed-dose combination of pertuzumab and trastuzumab with …

• CLINICAL_TRIALS trial_result · 2023-02-16
  Clinical Trial Update: Fulvestrant, Palbociclib and Erdafitinib in ER+/HER2-/FGFR-amplified Metastatic Breast Cancer [Phase 1]

  Phase 1 trial results for a three-drug combination of fulvestrant, palbociclib, and erdafitinib in ER+/HER2-/FGFR-amplified metastatic breas…

• CLINICAL_TRIALS trial_result · 2023-02-16
  Clinical Trial Update: Sintilimab and Bevacizumab Biosimilar Combined With PLD in mTNBC [Phase 2]

  A Phase 2 clinical trial evaluating sintilimab and bevacizumab biosimilar in combination with pegylated liposomal doxorubicin for metastatic…

• CLINICAL_TRIALS trial_result · 2023-02-15
  Clinical Trial Update: G1T38, a CDK 4/6 Inhibitor, in Combination With Fulvestrant in Hormone Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer [Phase 1, Phase 2]

  A phase 1/2 clinical trial evaluating G1T38 (a CDK 4/6 inhibitor) in combination with fulvestrant for HR-positive, HER2-negative locally adv…

• CLINICAL_TRIALS trial_result · 2023-02-13
  Clinical Trial Update: Disitamab Vedotin(RC48) Combined With Penpulimab(AK105) for Neoadjuvant Treatment of HER2-low Breast Cancer [Phase 2]

  A phase 2 clinical trial evaluating disitamab vedotin combined with penpulimab as neoadjuvant therapy for HER2-low breast cancer is underway…

• CLINICAL_TRIALS trial_result · 2023-02-10
  Clinical Trial Update: A Study to Characterize Colon Pathology in Patients With HER2 Amplified Breast Cancer Treated With Neratinib [Phase 2]

  Phase 2 trial updating colon pathology in patients with HER2-amplified breast cancer treated with neratinib has completed, with results post…

• CLINICAL_TRIALS trial_result · 2023-02-10
  Clinical Trial Update: NSAID Effects on Clinical and Imaging Breast Biomarkers [Phase 2]

  Phase 2 trial evaluating NSAID effects on clinical and imaging breast biomarkers; completed with results posted in 2023.

• CLINICAL_TRIALS trial_result · 2023-02-10
  Clinical Trial Update: DWI in Assessing Treatment Response in Patients With Breast Cancer Receiving Neoadjuvant Chemotherapy [NA]

  Clinical trial update on using diffusion-weighted imaging to assess treatment response in breast cancer patients receiving neoadjuvant chemo…

• CLINICAL_TRIALS trial_result · 2023-02-09
  Clinical Trial Update: The Ultrasound-guided Multiple-injection Costotransverse Block for Mastectomy and Primary Reconstructive Surgery. [Phase 4]

  Phase 4 clinical trial evaluating ultrasound-guided multiple-injection costotransverse block for mastectomy and primary reconstructive surge…