Breast Cancer

• CLINICAL_TRIALS trial_result · 2023-04-27
  Clinical Trial Update: Targeted T Cells After Neoadjuvant Chemotherapy in Treating Women With Stage II or III Breast Cancer Undergoing Surgery [Phase 2]

  Phase 2 trial update on targeted T cells after neoadjuvant chemotherapy in women with stage II or III breast cancer undergoing surgery has b…

• CLINICAL_TRIALS trial_result · 2023-04-25
  Clinical Trial Update: Efficacy of Supplement Adjuvant Capecitabine in HR+/HER2- Breast Cancer Patients With High Risks [Phase 3]

  Phase 3 trial update assessing efficacy of capecitabine as adjuvant therapy in high-risk HR+/HER2- breast cancer.

• CLINICAL_TRIALS trial_result · 2023-04-24
  Clinical Trial Update: ANG1005 in Leptomeningeal Disease From Breast Cancer [Phase 3]

  Phase 3 clinical trial update for ANG1005 in leptomeningeal disease from breast cancer (leptomeningeal carcinomatosis/metastases).

• CLINICAL_TRIALS trial_result · 2023-04-21
  Clinical Trial Update: Copper Cu 64 Anti-CEA Monoclonal Antibody M5A PET in Diagnosing Patients With CEA Positive Cancer [NA]

  Clinical trial update for M5A, a Copper-64 labeled anti-CEA monoclonal antibody used in PET imaging to diagnose CEA-positive cancers; the st…

• CLINICAL_TRIALS trial_result · 2023-04-20
  Clinical Trial Update: Accelerated Radiation Therapy After Surgery in Treating Patients With Breast Cancer [Phase 2]

  Phase 2 trial evaluating accelerated radiation therapy after surgery for breast cancer; study completed with results posted.

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• CLINICAL_TRIALS trial_result · 2023-04-20
  Clinical Trial Update: 99mTc-ADAPT6 SPECT-based Non-invasive Quantification of HER2-expression in Breast Cancer With Metastatic Lymph Nodes [Phase 2]

  Phase 2 clinical trial evaluating 99mTc-ADAPT6 SPECT imaging to quantify HER2-expression non-invasively in breast cancer with metastatic lym…

• CLINICAL_TRIALS trial_result · 2023-04-20
  Clinical Trial Update: Memantine for Prevention of Cognitive Decline in Patients With Breast Cancer [Phase 2]

  Phase 2 trial evaluating memantine to prevent cognitive decline in patients experiencing chemo-brain/Cognitive Decline after breast cancer t…

• CLINICAL_TRIALS trial_result · 2023-04-19
  Clinical Trial Update: Neoadjuvant Biomarker ResearcH Study of Palbociclib Combined With Endocrine Therapy in Estrogen Receptor Positive/HER2 Negative Breast CAncer (NeoRHEA) [Phase 2]

  Phase 2 neoadjuvant trial evaluating palbociclib with endocrine therapy in ER-positive/HER2-negative breast cancer has completed.

• CLINICAL_TRIALS trial_result · 2023-04-19
  Clinical Trial Update: Pembrolizumab and Doxorubicin Hydrochloride or Anti-Estrogen Therapy in Treating Patients With Triple-Negative or Hormone Receptor-Positive Metastatic Breast Cancer [Phase 2]

  Phase 2 trial evaluating pembrolizumab with doxorubicin or anti-estrogen therapy in metastatic breast cancer (both triple-negative and hormo…

• CLINICAL_TRIALS trial_result · 2023-04-18
  Clinical Trial Update: Herceptin Followed by Chemotherapy in Treating Women With Metastatic Breast Cancer That Overexpresses HER2 [Phase 3]

  Phase 3 trial update on Herceptin followed by chemotherapy for metastatic HER2-overexpressing breast cancer; study terminated.

• CLINICAL_TRIALS trial_result · 2023-04-18
  Clinical Trial Update: Safety and Efficacy of CEA-Targeted CAR-T Therapy for Relapsed/Refractory CEA+ Cancer [Phase 1, Phase 2]

  Early-phase trial update on a CEA-targeted CAR-T therapy for relapsed/refractory CEA-positive solid tumors, including lung and colorectal ca…

• CLINICAL_TRIALS trial_result · 2023-04-18
  Clinical Trial Update: Neoadjuvant Ontruzant (SB3) in Patients With HER2-positive Early Breast Cancer: An Open-Label (NeoON) [Phase 4]

  Open-label Phase 4 neoadjuvant trial update evaluating Ontruzant (SB3) in HER2-positive early breast cancer.

• CLINICAL_TRIALS trial_result · 2023-04-18
  Clinical Trial Update: Comprehensive Analysis of Spatial, Temporal and Molecular Patterns of Ribociclib Efficacy and Resistance in Advanced Breast Cancer Patients [Phase 4]

  Phase 4 clinical trial updating on ribociclib efficacy and resistance patterns in advanced breast cancer.

• CLINICAL_TRIALS trial_result · 2023-04-18
  Clinical Trial Update: Vaccine Therapy With or Without Polysaccharide-K in Patients With Stage IV HER2 Positive Breast Cancer Receiving HER2-Targeted Monoclonal Antibody Therapy [Phase 1, Phase 2]

  A Phase 1/2 trial evaluating a vaccine therapy with or without Polysaccharide-K in patients with stage IV HER2-positive breast cancer receiv…

• CLINICAL_TRIALS trial_result · 2023-04-18
  Clinical Trial Update: Assessing ImmunoResponse Post Eribulin: Eribulin and Immunogenicity in Advanced Breast Cancer [Phase 4]

  Phase 4 clinical trial evaluating immunogenicity response after eribulin treatment in advanced/metastatic breast cancer.

• CLINICAL_TRIALS trial_result · 2023-04-14
  Clinical Trial Update: Chidamide Combined With Fulvestrant for HR+/HER2-advanced Breast Cancer [Phase 2]

  A Phase 2 clinical trial evaluating chidamide in combination with fulvestrant for hormone receptor-positive, HER2-negative advanced breast c…

• CLINICAL_TRIALS trial_result · 2023-04-13
  Clinical Trial Update: PD-1 Knockout Anti-MUC1 CAR-T Cells in the Treatment of Advanced Breast Cancer [Phase 1, Phase 2]

  Phase 1/2 clinical trial evaluating PD-1 knockout anti-MUC1 CAR-T cells for advanced breast cancer has completed.

• CLINICAL_TRIALS trial_result · 2023-04-13
  Clinical Trial Update: A Study of SHR6390 Combined With Famitinib in the Treatment of HR + / HER2- Advanced Breast Cancer. [Phase 2]

  A Phase 2 clinical trial evaluating SHR6390 in combination with famitinib for HR+/HER2- advanced/metastatic breast cancer is underway, with …

• CLINICAL_TRIALS trial_result · 2023-04-12
  Clinical Trial Update: A Phase II Trial of Camrelizumab in Combination With Apatinib and Eribulin in Patients With Advanced TNBC [Phase 2]

  A Phase II trial evaluating camrelizumab in combination with apatinib and eribulin for advanced breast cancer is ongoing; results are not ye…

• CLINICAL_TRIALS trial_result · 2023-04-12
  Clinical Trial Update: Select the Appropriate Population for Adding CDK4/6i to Neoadjuvant Endocrine Therapy [Phase 4]

  Phase 4 trial update evaluating selecting the appropriate population for adding a CDK4/6 inhibitor to neoadjuvant endocrine therapy in local…

• CLINICAL_TRIALS trial_result · 2023-04-12
  Clinical Trial Update: Prehabilitation for Women Undergoing Pre-operative Chemotherapy for Breast Cancer [Phase 2, Phase 3]

  Phase 2/3 clinical trial update on prehabilitation for women undergoing pre-operative chemotherapy for breast cancer has completed.

• CLINICAL_TRIALS trial_result · 2023-04-12
  Clinical Trial Update: SHR6390 Combined With Anastrozole for Preoperative Treatment of Breast Cancer. [Phase 2]

  A Phase 2 clinical trial evaluating SHR6390 in combination with anastrozole as preoperative treatment for breast cancer has completed.

• CLINICAL_TRIALS trial_result · 2023-04-12
  Clinical Trial Update: A Phase II Trial of Camrelizumab in Combination With Apatinib for Neoadjuvant Treatment of Early-stage TNBC With a High Proportion of TILs [Phase 2]

  Phase II trial evaluating camrelizumab plus apatinib as neoadjuvant therapy for early-stage triple-negative breast cancer with high tumor-in…

• CLINICAL_TRIALS trial_result · 2023-04-11
  Clinical Trial Update: Alternative Exercise Program to Improve Skeletal Muscle Function and Fatigue in Cancer Survivors [NA]

  A completed clinical trial evaluating an alternative exercise program to improve skeletal muscle function and fatigue in breast cancer survi…

• CLINICAL_TRIALS trial_result · 2023-04-10
  Clinical Trial Update: Bintrafusp Alfa in High Mobility Group AT-Hook 2 (HMGA2) Expressing Triple Negative Breast Cancer [Phase 2]

  Phase 2 trial of Bintrafusp Alfa in HMGA2-expressing triple-negative breast cancer was terminated; results have been posted.