Breast Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: A Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-0587 as a Monotherapy and in Combination With Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive and Human Epidermal Growth Factor Receptor 2-Negative (ER+/HER2-) Breast Cancer [Phase 1]
This Phase 1 trial, sponsored by Genentech, evaluates the safety, pharmacokinetics, and activity of GDC-0587 as a monotherapy and in combina…
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CLINICAL_TRIALS trial_result · 2026-04-03Clinical Trial Update: Tucatinib+Trastuzumab+Eribulin in HER2+ MBC [Phase 2]
A Phase 2 clinical trial evaluating tucatinib in combination with trastuzumab and eribulin for HER2-positive breast cancer is currently recr…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer [Phase 3]
Phase 3 trial evaluating whether adding inavolisib with a CDK4/6 inhibitor and letrozole improves efficacy and safety versus placebo with a …
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Investigation of the Effects of Serratus Posterior Superior Intercostal Plane Block and Serratus Anterior Plane Block on Perioperative Analgesia Management in Patients Scheduled for Mastectomy [NA]
A clinical trial is evaluating the effects of serratus posterior superior intercostal plane block and serratus anterior plane block on perio…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Mobile Health for Adherence in Breast Cancer Patients [NA]
Clinical trial evaluating a mobile health tool to support adherence in breast cancer patients is currently recruiting, including HER2-negati…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Margin Optimisation Using Z-axis Assessment With Real-time Tomosynthesis (MOZART Study). [NA]
The MOZART study assesses margin optimization using Z-axis assessment with real-time tomosynthesis in breast cancer and is currently recruit…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: DIEP Flap Breast Reconstruction: Perioperative Biomarkers and Outcomes
This trial update indicates ongoing recruitment for a study evaluating perioperative biomarkers and outcomes in DIEP flap breast reconstruct…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Partial Breast Re-irradiation Using Ultra Hypofractionation (PRESERVE) [NA]
The PRESERVE trial, sponsored by the University Health Network in Toronto, is evaluating partial breast re-irradiation using ultra-hypofract…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Same-Day Awake Mastectomy With Immediate Breast Reconstruction for Patients With Breast Cancer [NA]
A University of Rome Tor Vergata trial is examining same-day awake mastectomy with immediate breast reconstruction for breast cancer, incorp…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Elacestrant + Everolimus in Patients ER+/HER2-, ESR1mut, Advanced Breast Cancer Progressing to ET and CDK4/6i. [Phase 3]
A Phase 3 trial evaluating the combination of elacestrant and everolimus in ER-positive, HER2-negative advanced breast cancer with ESR1 muta…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: A Study to Assess CLBR001+ABBV-461 in Subjects With Locally Advanced or Metastatic Breast Cancer [Phase 1]
This clinical trial update describes a Phase 1 study evaluating the combination CLBR001 and ABBV-461 for locally advanced or metastatic brea…
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CLINICAL_TRIALS withdrawal · 2026-04-03Clinical Trial Update: Assessment of Current Biomarker Testing Practices for Common Solid Cancers in Precision Oncology in the Community Setting
The ECOG-ACRIN trial assessing biomarker testing practices for common solid cancers in community oncology settings has been withdrawn.
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CLINICAL_TRIALS trial_result · 2026-04-02Clinical Trial Update: Contrast-Enhanced Ultrasound Scan for the Estimation of Tissue Pressure in Patients With Breast Cancer [EARLY_Phase 1]
Early Phase 1 trial assessing contrast-enhanced ultrasound to estimate tissue pressure in patients with breast cancer; results have been pos…
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CLINICAL_TRIALS trial_result · 2026-04-02Clinical Trial Update: A Study of Imlunestrant Versus Standard Endocrine Therapy in Participants With Early Breast Cancer [Phase 3]
This is a Phase 3 clinical trial update comparing Imlunestrant with standard endocrine therapy in patients with early breast cancer.
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: A Study to Investigate the Efficacy and Safety of Letrozole SIE Compared With Femara® (Both Combined With the CDK4/6 Inhibitor Ribociclib) in Postmenopausal Women With HR-Positive, HER2-Negative, Inoperable Locally Advanced or Metastatic Breast Cancer [Phase 3]
A Phase 3 trial is planned to compare Letrozole SIE with Femara, both in combination with ribociclib, in postmenopausal women with HR-positi…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Tumor Treating Fields for the Treatment of Leptomeningeal Metastases of the Spine in Patients With Breast or Lung Cancer [NA]
A Mayo Clinic-sponsored trial is evaluating Tumor Treating Fields (TTFields) delivered via the Optune device for leptomeningeal metastases i…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer [Phase 3]
Phase 3 study evaluating RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant for locally advanced or metastatic PIK3CA-mutant HR+/HER2- bre…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Study to Evaluate Efficacy & Safety of Afuresertib Plus Fulvestrant in Patients With Locally Advanced or Metastatic HR+/HER2- Breast Cancer [Phase 3]
A Phase 3 trial evaluating afuresertib plus fulvestrant in locally advanced or metastatic HR+/HER2- breast cancer is currently active but no…
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CLINICAL_TRIALS trial_result · 2026-04-02Clinical Trial Update: Mammography Screening With Artificial Intelligence (MASAI) [NA]
The MASAI trial evaluating mammography screening with artificial intelligence has completed.
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Study Assessing the Efficacy and Safety of Treatment With Alpelisib Plus Fulvestrant Versus Placebo Plus Fulvestrant in Chinese Men and Postmenopausal Women With Advanced Breast Cancer [Phase 2]
A Phase 2 clinical trial update describes an ongoing study evaluating alpelisib plus fulvestrant versus placebo plus fulvestrant in Chinese …
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: A Phase III Randomised Study to Evaluate Dato-DXd and Durvalumab for Neoadjuvant/Adjuvant Treatment of Triple-Negative or Hormone Receptor-low/HER2-negative Breast Cancer [Phase 3]
A Phase III randomized trial evaluating Dato-DXd in combination with Durvalumab for neoadjuvant/adjuvant treatment in triple-negative or hor…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Cancer Genetic Testing in Ethnic Populations [NA]
A Mayo Clinic-sponsored clinical trial update on cancer genetic testing across multiple cancer types in diverse ethnic populations; the stud…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: A Study of Language Interpretation Solutions for People With Breast Cancer [NA]
This clinical trial entry indicates a study sponsored by Memorial Sloan Kettering Cancer Center evaluating language interpretation solutions…
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CLINICAL_TRIALS trial_result · 2026-04-02Clinical Trial Update: Monitoring Symptoms to Help Young Women Take Hormone Therapy for Stage I-III Breast Cancer, ASPEN Study [NA]
A clinical trial update for ASPEN (NCT05568472) describing ongoing monitoring to help young women adhere to adjuvant hormone therapy in stag…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: A Study to Understand the Patients Confirmed to Have Advanced or Metastatic Breast Cancer and Receiving Palbociclib Treatment Using a Real-world Database
A completed real-world database study sponsored by Pfizer aims to characterize patients with advanced or metastatic breast cancer who are tr…