Breast Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-08-05Clinical Trial Update: Pyrotinib Combined With Trastuzumab Subcutaneously Compared Intravenous Administration in the Treatment of HER2-positive Early Breast Cancer
This clinical trial evaluates subcutaneous pyrotinib combined with trastuzumab versus intravenous administration for HER2-positive early bre…
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CLINICAL_TRIALS research · 2024-08-05Clinical Trial Update: Neoadjuvant Trastuzumab Deruxtecan (T-DXd) With Response-directed Definitive Therapy in Early Stage HER2-positive Breast Cancer (SHAMROCK Study) [Phase 2]
This clinical trial update describes the SHAMROCK study, a phase II neoadjuvant treatment using trastuzumab deruxtecan (T-DXd) followed by r…
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CLINICAL_TRIALS other · 2024-08-05Clinical Trial Update: Single Fraction Preoperative Radiotherapy for Early Stage Breast Cancer [NA]
This clinical trial update describes a study evaluating single-fraction preoperative radiotherapy for early-stage breast cancer, which is cu…
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CLINICAL_TRIALS trial_result · 2024-08-05Clinical Trial Update: RADIOSO MILAN I (RADar Reflector localisatiOn-SCOUT for carcinOma Mammae, the MILAN IEO Experience I)
Clinical trial update for the RADIOSO MILAN I study, evaluating the RADar Reflector localization-SCOUT system for breast cancer, currently r…
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CLINICAL_TRIALS trial_result · 2024-08-02Clinical Trial Update: Neoadjuvant Treatment of Locally-advanced Breast Cancer Patients With Ribociclib and Letrozole [Phase 2]
Phase 2 neoadjuvant trial evaluating ribociclib with letrozole in locally advanced, ER-positive, HER2-negative breast cancer has completed.
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CLINICAL_TRIALS trial_result · 2024-08-02Clinical Trial Update: HER-2 Pulsed DC Vaccine to Prevent Recurrence of Invasive Breast Cancer Post Neoadjuvant Chemotherapy [Phase 1]
This update reports the completion of a Phase 1 trial evaluating a HER-2 pulsed dendritic cell vaccine to prevent recurrence of invasive bre…
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CLINICAL_TRIALS trial_result · 2024-08-02Clinical Trial Update: Biofeedback Training on Shoulder Muscles Strength Post Mastectomy [NA]
A completed Cairo University–sponsored clinical trial evaluated whether biofeedback training can improve shoulder muscle strength after mast…
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CLINICAL_TRIALS trial_result · 2024-08-02Clinical Trial Update: Longitudinal Study of Behavioral Changes, Economic and Sociological After CAncer [NA]
A completed longitudinal clinical trial update examining behavioral, economic, and sociological outcomes after cancer, covering breast cance…
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CLINICAL_TRIALS other · 2024-08-02Clinical Trial Update: Gut and Tumor Microbiome in Patients With Early Stage (II-III), Locally Advanced or Advanced ER-positive and HER2-negative Breast Cancer.
A clinical trial evaluating gut and tumor microbiome in patients with ER-positive, HER2-negative breast cancer across stages II-III to advan…
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CLINICAL_TRIALS trial_result · 2024-08-01Clinical Trial Update: Trilaciclib, a CDK 4/6 Inhibitor, in Patients Receiving Gemcitabine and Carboplatin for Metastatic Triple-Negative Breast Cancer (TNBC) [Phase 3]
Phase 3 trial evaluating trilaciclib in combination with gemcitabine and carboplatin for metastatic triple-negative breast cancer has comple…
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CLINICAL_TRIALS trial_result · 2024-08-01Clinical Trial Update: Study of the Molecular Features of Postmenopausal Women With HR+ HER2-negative aBC on First-line Treatment With Ribociclib and Letrozole and, in Patients With a PIK3CA Mutation, on Second-line Treatment With Alpelisib Plus Fulvestrant [Phase 3]
Phase 3 trial update evaluating molecular features in postmenopausal women with HR+/HER2-negative advanced breast cancer treated first-line …
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CLINICAL_TRIALS research · 2024-08-01Clinical Trial Update: First-line Gemcitabine Plus Cisplatin in Locally Advanced (IIIC Stage) Breast Cancer Patients [Phase 2]
A Phase 2 clinical trial registry entry indicating an ongoing study of first-line gemcitabine plus cisplatin for locally advanced breast can…
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CLINICAL_TRIALS trial_result · 2024-08-01Clinical Trial Update: Evaluation of the Safety and Tolerability of Niraparib With Everolimus in Advanced Gynecologic Malignancies and Breast [Phase 1]
Phase 1 study evaluating safety and tolerability of combining Niraparib with Everolimus in advanced gynecologic malignancies and breast canc…
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CLINICAL_TRIALS trial_result · 2024-08-01Clinical Trial Update: GM1 Prophylaxis for Post-chemotherapy Cognitive Impairment in Patients With Early Operable Breast Cancer [Phase 3]
A Phase 3 clinical trial evaluating GM1 prophylaxis to prevent chemotherapy-induced cognitive impairment in patients with early operable bre…
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CLINICAL_TRIALS trial_result · 2024-08-01Clinical Trial Update: GM1 Prophylaxis for WBRT Related Cognitive Dysfunction [Phase 3]
A Phase 3 trial evaluating GM1 ganglioside prophylaxis to prevent whole-brain radiotherapy-related cognitive dysfunction in patients with br…
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CLINICAL_TRIALS research · 2024-08-01Clinical Trial Update: Phase III Study :SHR6390/Placebo Combined With Endocrine Therapy for the Adjuvant Treatment of Hormone Receptor Positive,Human Epidermal Receptor 2 Negative [Phase 3]
Phase III trial status update for SHR6390 in combination with placebo and endocrine therapy as adjuvant treatment for hormone receptor-posit…
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CLINICAL_TRIALS research · 2024-08-01Clinical Trial Update: A Study of XS-02 Capsules in Patients With Advanced Solid Tumors [Phase 1, Phase 2]
This clinical trial update covers XS-02 capsules in advanced solid tumors (including ovarian, breast, and endometrial cancers) in Phase 1/2,…
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EMA approval · 2024-07-31EMA Authorised: Taxotere (docetaxel) — Sanofi Winthrop Industrie
The EMA authorised Taxotere (docetaxel) for multiple cancer indications including head and neck cancer, non-small cell lung cancer, gastric …
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: Implication of CCR4-NOT Complex Subunit 7 Expression in Natural Killer Cell Resistance in Metastatic Breast Cancer
Clinical trial update from Ain Shams University examining whether CCR4-NOT complex subunit 7 expression influences natural killer cell resis…
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: Investigation of Genetic Determinants of Capecitabine Toxicity
This document reports a completed clinical trial investigating genetic determinants of capecitabine toxicity in patients with breast cancer.
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CLINICAL_TRIALS research · 2024-07-31Clinical Trial Update: Real-world Study on the Management of Hematological Toxicities Associated With Targeted Therapies for Breast Cancer
A real-world study sponsored by Fudan University aims to evaluate management strategies for hematological toxicities arising from targeted t…
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CLINICAL_TRIALS research · 2024-07-31Clinical Trial Update: A Single Arm Clinical Study of Dendritic Cell Vaccine Loaded With Circular RNA Encoding Cryptic Peptide for Patients With HER2-negative Advanced Breast Cancer [Phase 1]
A Phase 1, single-arm clinical trial evaluating a dendritic cell vaccine loaded with circular RNA encoding a cryptic peptide for patients wi…
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: Clinical Utility of FES F18 PET/CT in Metastatic Breast Cancer Patients
A GE Healthcare-sponsored trial evaluating the clinical utility of 18F-fluoroestradiol (FES) PET/CT in metastatic breast cancer has been ter…
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CLINICAL_TRIALS research · 2024-07-31Clinical Trial Update: A RCT of Psychosocial Interventions Facilitating Positive Psychological Adaptation in Breast Cancer [NA]
This entry notes a randomized controlled trial evaluating psychosocial interventions to promote positive psychological adaptation in women w…
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: Self-monitoring Activity: a Randomized Trial of Game-oriented Applications [NA]
Randomized trial evaluating a game-oriented self-monitoring activity application; the study is completed with results posted in 2024, involv…