Breast Cancer
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: Aromatase Inhibitor Therapy With or Without Fulvestrant for the Treatment of HR Positive Metastatic Breast Cancer With an ERS1 Activating Mutation, the INTERACT Study [Phase 2]
This Phase 2 INTERACT trial evaluated adding fulvestrant to aromatase inhibitor therapy for HR-positive metastatic breast cancer with an ESR…
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: Magnesium Sulphate Versus Ketamine as an Adjuvant to Bupivacaine in Pectoral Nerve Block During Mastectomy [Phase 2]
Phase 2 trial comparing magnesium sulfate versus ketamine as adjuvants to bupivacaine for pectoral nerve block in mastectomy; the study has …
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: Assessment of Complete Pathologic Response After Neoadjuvant Chemotherapy for Breast Cancer
This clinical trial update reports on the assessment of complete pathologic response after neoadjuvant chemotherapy in breast cancer. The st…
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CLINICAL_TRIALS trial_result · 2024-12-27Clinical Trial Update: An Escape Room Intervention to Help Improve Breast Cancer Patients' Ability to Navigate Online Access to Nutrition Information [NA]
A completed clinical trial at Fred Hutchinson Cancer Center evaluated an escape room intervention to help breast cancer patients navigate on…
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CLINICAL_TRIALS research · 2024-12-27Clinical Trial Update: Efficacy of the Serratus Posterior Superior Intercostal Plane Block for Postoperative Analgesia in Breast Cancer Surger.(SPSIP) Block is a Novel Regional Anesthesia Technique Targeting the Dorsal Rami and Intercostal Nerves (T2-T6), Providing Sensory Blockade to Both the Posterior and Lateral Aspect [NA]
This entry reports on a clinical trial evaluating the efficacy of the Serratus Posterior Superior Intercostal Plane (SPSIP) block for postop…
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CLINICAL_TRIALS research · 2024-12-27Clinical Trial Update: Chidamide Combined With Angiogenesis Inhibitors and Fulvestrant for Advanced HR-positive, HER2-negative Breast Cancer [Phase 2]
A Phase 2 clinical trial is evaluating chidamide in combination with angiogenesis inhibitors and fulvestrant for advanced HR-positive, HER2-…
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CLINICAL_TRIALS research · 2024-12-27Clinical Trial Update: Percent Weight Change in the Medical Supplement Group of Early Breast Cancer [NA]
This clinical trial update reports on weight change in the medical supplement group for patients with early-stage breast cancer, with the tr…
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FDA approval · 2024-12-26FDA Approved: CYCLOPHOSPHAMIDE — Original Application (Slate Run Pharmaceuticals, LLC)
FDA approves Slate Run Pharmaceuticals' original application for CYCLOPHOSPHAMIDE FOR INJECTION, expanding the market for a generic cyclopho…
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CLINICAL_TRIALS trial_result · 2024-12-24Clinical Trial Update: Chemotherapy Before Surgery and Tissue Sample Collection in Patients With Stage IIA-IIIC Breast Cancer [NA]
This clinical trial update reports the termination of a study evaluating chemotherapy before surgery and tissue sample collection in patient…
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CLINICAL_TRIALS research · 2024-12-24Clinical Trial Update: Dosimetric Comparison of Target Volume, Heart and Left Lung in Post Mastectomy Radiotherapy (RT) of Left Sided Breast Cancer by Free Breathing (FB) Versus Deep Inspiration Breath Hold (DIBH) Technique [NA]
A dosimetric study comparing free breathing versus deep inspiration breath hold techniques for left-sided postmastectomy radiotherapy in bre…
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CLINICAL_TRIALS trial_result · 2024-12-24Clinical Trial Update: Oral AMXT 1501 Dicaprate in Combination With IV DFMO [Phase 1, Phase 2]
A Phase 1/2 trial of oral AMXT 1501 dicaprate in combination with IV DFMO has been terminated.
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CLINICAL_TRIALS other · 2024-12-24Clinical Trial Update: The EMBRACE Study The EMBRACE Study
The EMBRACE Study is a recruiting clinical trial sponsored by the University of Aberdeen for breast cancer.
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FDA approval · 2024-12-20FDA Approved: IBRANCE — Supplemental Application (Pfizer Laboratories Div Pfizer Inc)
FDA approved a supplemental application for IBRANCE (palbociclib) submitted by Pfizer Laboratories Div Pfizer Inc.
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CLINICAL_TRIALS trial_result · 2024-12-20Clinical Trial Update: Alcohol and Breast Cancer (ABC) Trial [NA]
The Alcohol and Breast Cancer (ABC) trial evaluating the relationship between alcohol exposure and outcomes in estrogen receptor-positive br…
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CLINICAL_TRIALS research · 2024-12-20Clinical Trial Update: Super Hypofractionated Irradiation for Whole Breast Treatment [NA]
This document provides a clinical trial update on super hypofractionated irradiation for whole-breast treatment in breast cancer. The study …
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CLINICAL_TRIALS research · 2024-12-20Clinical Trial Update: Abemaciclib, Palbociclib or Dalpiciclib Combined with Endocrine Therapy As First-line Treatment in HR Positive, HER2 Negative Unresectable or Metastatic Breast Cancer
A clinical trial update for first-line treatment of HR-positive, HER2-negative unresectable or metastatic breast cancer testing abemaciclib,…
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CLINICAL_TRIALS trial_result · 2024-12-20Clinical Trial Update: Study of SHR-A1921 Combined Adebrelimab in HR-positive, HER2-negative Advanced Breast Cancer [Phase 2]
Phase 2 clinical trial evaluating SHR-A1921 in combination with Adebrelimab for advanced hormone-receptor-positive, HER2-negative breast can…
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CLINICAL_TRIALS research · 2024-12-20Clinical Trial Update: Comparative Evaluation of Diffusion Weighted MRI And Ultrasonography In The Detection of Breast Lesions
A comparative study evaluates diffusion-weighted MRI versus ultrasonography for detecting breast lesions; the trial is sponsored by Superior…
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CLINICAL_TRIALS research · 2024-12-20Clinical Trial Update: Increasing Oral Medication Adherence for Metastatic Breast Cancer Patients
A clinical trial update notes a study focused on increasing adherence to oral therapy in metastatic breast cancer patients and is currently …
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CLINICAL_TRIALS other · 2024-12-20Clinical Trial Update: Hemopatch Implication After Axillary Dissection for Breast Cancer [NA]
A Hemopatch-based clinical study following axillary dissection for breast cancer is noted. The trial status is not yet recruiting.
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CLINICAL_TRIALS research · 2024-12-19Clinical Trial Update: Body Image and Physical Activity of Women with Breast Cancer
This clinical trial update indicates ongoing recruitment for a study on body image and physical activity in women with breast cancer, sponso…
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FDA approval · 2024-12-19FDA Approved: CYCLOPHOSPHAMIDE — Original Application (BluePoint Laboratories)
FDA approved BluePoint Laboratories' original ANDA for cyclophosphamide, establishing a generic version of the chemotherapy agent.
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CLINICAL_TRIALS research · 2024-12-19Clinical Trial Update: Comparison of Axillary Sentinel Lymph Node Biopsy Versus no Axillary Surgery [NA]
This clinical trial is investigating whether axillary sentinel lymph node biopsy offers any advantage over omitting axillary surgery in brea…
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CLINICAL_TRIALS trial_result · 2024-12-18Clinical Trial Update: Assessing the Benefit of Art & Music Therapy on Quality of Life in Patients With Breast Cancer [NA]
Clinical trial evaluating the benefit of art and music therapy on quality of life in breast cancer patients has completed.
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CLINICAL_TRIALS other · 2024-12-18Clinical Trial Update: Panther: A Study Comparing Biweekly and Tailored EC-T Versus Three Weekly FEC-T in Breast Cancer Patients [Phase 3]
A Phase 3 study (Panther) compares biweekly and tailored EC-T chemotherapy against three-weekly FEC-T in breast cancer patients.