Breast Cancer

CLINICAL_TRIALS research · 2025-04-04

Clinical Trial Update: A Feasibility Study of Topical Cannabinoids for Treatment of Aromatase Inhibitor-Associated Musculoskeletal Syndrome (AIMSS) in Adults With Hormone Receptor-Positive Breast Cancer (CanAroma) [EARLY_Phase 1]

This is a completed early-phase feasibility study (CanAroma) evaluating topical cannabinoids for aromatase inhibitor-associated musculoskele…

CLINICAL_TRIALS trial_result · 2025-04-04

Clinical Trial Update: The Effect of Roy Adaptation Model-Based Nursing Interventions on Psychological Resilience and Psychosocial Adjustment in Newly Diagnosed Breast Cancer Patients: A Randomized Controlled Trial [NA]

A randomized controlled trial evaluated Roy Adaptation Model-based nursing interventions to improve psychological resilience and psychosocia…

CLINICAL_TRIALS research · 2025-04-04

Clinical Trial Update: INCMGA00012 and Pelareorep for the Treatment of Metastatic Triple Negative Breast Cancer, IRENE Study [Phase 2]

Phase 2 clinical trial NCT04445844 (IRENE study) combines INCMGA00012 with Pelareorep for metastatic triple-negative breast cancer; the stud…

CLINICAL_TRIALS trial_result · 2025-04-04

Clinical Trial Update: Application of EndoScell Intraoperative Cellular Probing Technology for Early-Stage Breast Cancer [NA]

A clinical trial is evaluating the EndoScell intraoperative cellular probing technology for early-stage breast cancer; recruitment is curren…

CLINICAL_TRIALS research · 2025-04-04

Clinical Trial Update: Cognitive Training and Brain Stimulation in Women With Post-chemotherapy Cognitive Impairment [NA]

A clinical trial is recruiting to evaluate cognitive training and brain stimulation for post-chemotherapy cognitive impairment in women with…

CLINICAL_TRIALS research · 2025-04-04

Clinical Trial Update: Evaluation of the Feasibility of a Study Comparing Local Anesthesia and General Anesthesia in Conservative Surgery for Breast Cancer [NA]

This clinical trial update outlines a feasibility study comparing local anesthesia with general anesthesia for conservative breast cancer su…

CLINICAL_TRIALS trial_result · 2025-04-03

Clinical Trial Update: Study to Investigate the Chemotherapy-Induced Peripheral Neuropathy (CIPN) Onset-Suppressing Effect and Safety of ONO-2910 in Patients With Breast Cancer Receiving Weekly Paclitaxel [Phase 2]

Phase 2 study evaluating ONO-2910 for suppressing the onset of chemotherapy-induced peripheral neuropathy in breast cancer patients receivin…

CLINICAL_TRIALS trial_result · 2025-04-03

Clinical Trial Update: Study of Seribantumab in Adult Patients With NRG1 Gene Fusion Positive Advanced Solid Tumors [Phase 2]

A Phase 2 study of seribantumab in adults with NRG1 gene fusion-positive advanced solid tumors has been terminated, with results posted in A…

CLINICAL_TRIALS trial_result · 2025-04-03

Clinical Trial Update: PERSONAL - Sleep In Breast Cancer

A completed clinical trial (NCT05093426) by Closed Loop Medicine evaluating sleep in breast cancer patients; results were posted on 2025-04-…

CLINICAL_TRIALS trial_result · 2025-04-03

Clinical Trial Update: The Effect of Hyperbaric OxygeN Therapy on brEast Cancer Patients With Late Radiation toxicitY - UMBRELLA HONEY Trial [Phase 3]

Phase 3 trial evaluating hyperbaric oxygen therapy in breast cancer patients with late radiation toxicity has completed. The document provid…

CLINICAL_TRIALS trial_result · 2025-04-03

Clinical Trial Update: Effect of Anthracyclines and Cyclophosphamide on Cardiovascular Responses [NA]

A completed clinical trial from the University of São Paulo assesses how anthracyclines and cyclophosphamide influence cardiovascular respon…

CLINICAL_TRIALS research · 2025-04-03

Clinical Trial Update: Evaluate the Efficacy and Safety of Adebrelimab Combined With Chemotherapy With or Without Radiotherapy as Neoadjuvant Treatment for HER2-Negative Locally Advanced Breast Cancer [Phase 2]

Phase 2 neoadjuvant trial evaluating Adebrelimab with chemotherapy with or without radiotherapy for HER2-negative locally advanced breast ca…

CLINICAL_TRIALS research · 2025-04-03

Clinical Trial Update: Accelerated Partial Breast Irradiation Using External Beam Volumetric Modulated Arc Therapy (VMAT): a Randomised Non-inferiority Trial of 30 Gy Versus 26 Gy in Five Fractions Investigating Patient-reported Outcomes [NA]

Protocol for a randomized non-inferiority trial comparing 30 Gy versus 26 Gy in five fractions of accelerated partial breast irradiation usi…

CLINICAL_TRIALS research · 2025-04-03

Clinical Trial Update: Al18F-HER2-BCH PET in Breast Patients Treated With Neoadjuvant Therapy [NA]

A clinical trial update for an Al18F-HER2-BCH PET imaging tracer in breast cancer patients treated with neoadjuvant therapy; the study (NCT0…

CLINICAL_TRIALS research · 2025-04-03

Clinical Trial Update: Photoacoustic/Ultrasound Imaging for Breast Nodule Diagnosis, Molecular Classification, and Neoadjuvant Chemotherapy Response Evaluation [NA]

This clinical trial investigates the use of photoacoustic and ultrasound imaging to diagnose breast nodules, classify molecular subtypes of …

CLINICAL_TRIALS trial_result · 2025-04-02

Clinical Trial Update: Study of Trastuzumab Deruxtecan (T-DXd) vs Investigator's Choice Chemotherapy in HER2-low, Hormone Receptor Positive, Metastatic Breast Cancer [Phase 3]

A Phase 3 trial evaluating trastuzumab deruxtecan (T-DXd) versus investigator's choice chemotherapy in patients with HER2-low, hormone recep…

FDA approval · 2025-04-02

FDA Approved: PERJETA — Supplemental Application (Genentech, Inc.)

FDA approved a supplemental application for PERJETA (pertuzumab) submitted by Genentech, Inc.

CLINICAL_TRIALS trial_result · 2025-04-02

Clinical Trial Update: Study to Evaluate the Efficacy and Safety of Neoadjuvant Treatment Based on Dual Blockade With Pertuzumab and the Trastuzumab Biosimilar CT-P6 (Herzuma®) in Early HER2-positive Breast Cancer in Routine Clinical Practice [NA]

A completed clinical trial evaluating neoadjuvant dual HER2 blockade with pertuzumab and the trastuzumab biosimilar CT-P6 (Herzuma) in early…