Breast Cancer

• CLINICAL_TRIALS research · 2025-04-25
  Clinical Trial Update: UTD1 Combined With Capecitabine in Metastatic HER2-negative Breast Cancer Patients With Brain Metastases [Phase 1, Phase 2]

  This clinical trial update reports a Phase 1/2 study of UTD1 in combination with Capecitabine for metastatic HER2-negative breast cancer wit…

• CLINICAL_TRIALS research · 2025-04-25
  Clinical Trial Update: A ReaL World Study of DS-8201

  This update reports a real-world study of DS-8201 (trastuzumab deruxtecan) for metastatic breast cancer; the study is currently active but n…

• CLINICAL_TRIALS research · 2025-04-25
  Clinical Trial Update: Reflects the Intervention (AI Chatbot) [NA]

  A planned clinical trial evaluating an AI chatbot intervention for early-stage breast cancer has not yet begun recruitment.

• CLINICAL_TRIALS research · 2025-04-25
  Clinical Trial Update: Exploring Breast Referral Behaviours in Primary Care [NA]

  A University of Nottingham–led clinical trial investigating primary care breast referral behaviours is not yet recruiting.

• CLINICAL_TRIALS research · 2025-04-24
  Clinical Trial Update: A Phase III Study of KN026 in Combination With HB1801 ± Carboplatin as Neoadjuvant Treatment for Early or Locally Advanced HER2-Positive Breast Cancer [Phase 3]

  A Phase 3 trial update announces recruitment for KN026 in combination with HB1801, with or without carboplatin, as neoadjuvant therapy for e…

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• CLINICAL_TRIALS research · 2025-04-24
  Clinical Trial Update: Testing Sacituzumab Govitecan Therapy in Patients With HER2-Negative Breast Cancer and Brain Metastases [Phase 2]

  A Phase 2 clinical trial is evaluating sacituzumab govitecan in patients with HER2-negative metastatic breast cancer and brain metastases; t…

• CLINICAL_TRIALS research · 2025-04-24
  Clinical Trial Update: LASER and Radiofrequency for Treatment of Vaginal Vulvar Atrophy (VVA) in Women Treated for Breast Cancer (EPMLARF-arm2) [NA]

  Clinical trial update indicating that LASER and radiofrequency treatment for vaginal/vulvar atrophy in women treated for breast cancer is cu…

• CLINICAL_TRIALS research · 2025-04-24
  Clinical Trial Update: The Immune Effects of Fermented Wheat Germ Nutritional Supplementation in Patients With Advanced Solid Tumor Cancers Being Treated With Standard of Care Checkpoint Inhibitors [Phase 1]

  Phase 1 trial update studying the immune effects of a fermented wheat germ extract added to standard checkpoint inhibitor therapy in patient…

• CLINICAL_TRIALS research · 2025-04-24
  Clinical Trial Update: Breast Cancer PET/CT Imaging With 68Ga-pAKTi

  Clinical trial update: PET/CT imaging with the radiotracer 68Ga-pAKTi is enrolling by invitation in breast cancer patients, including those …

• CLINICAL_TRIALS research · 2025-04-24
  Clinical Trial Update: Transcutaneous Electrical Nerve Stimulation in Chemotherapy Induced Peripheral Neuropathy in Patients With Stage I-III Early Stage Breast Cancer [NA]

  This clinical trial is evaluating transcutaneous electrical nerve stimulation for chemotherapy-induced peripheral neuropathy in patients wit…

• CLINICAL_TRIALS research · 2025-04-24
  Clinical Trial Update: SABR PRIMER - Evaluating Stereotactic Ablative Radiotherapy for Primary and Regional Breast Tumors [NA]

  This clinical trial update describes SABR PRIMER, evaluating stereotactic ablative radiotherapy for primary and regional breast tumors; the …

• CLINICAL_TRIALS research · 2025-04-24
  Clinical Trial Update: CPAP for Motion Management in Breast Radiotherapy; and Lung & Liver SABR [NA]

  This clinical trial update notes a study from Waikato Hospital evaluating CPAP-based motion management in breast radiotherapy and stereotact…

• CLINICAL_TRIALS research · 2025-04-23
  Clinical Trial Update: A Study of Sirolimus (Albumin-Bound) in Combination With Palbociclib and Fulvestrant for the Treatment of Advanced Breast Cancer [Phase 1]

  This Phase 1 trial assesses the safety of combining sirolimus (albumin-bound) with palbociclib and fulvestrant in patients with advanced bre…

• CLINICAL_TRIALS research · 2025-04-23
  Clinical Trial Update: OPTImaL:Optimisation of Treatment for Patients With Low Stage Triple-negative Breast Cancer With High Stromal Tumor-infiltrating Lymphocytes

  This entry describes a clinical trial named OPTImaL investigating optimized treatment for patients with early-stage triple-negative breast c…

• CLINICAL_TRIALS research · 2025-04-23
  Clinical Trial Update: Chemotherapy-free Trastuzumab and Pertuzumab in HER2-positive Breast Cancer: FDG-PET Response-adapted Strategy. [Phase 2]

  Phase 2 clinical trial in HER2-positive breast cancer evaluating a chemotherapy-free regimen of trastuzumab and pertuzumab guided by FDG-PET…

• CLINICAL_TRIALS research · 2025-04-23
  Clinical Trial Update: TNBC Gut Microbiota During Neoadjuvant Treatment [NA]

  This clinical trial update describes a study examining gut microbiota changes during neoadjuvant treatment for triple-negative breast cancer…

• CLINICAL_TRIALS research · 2025-04-22
  Clinical Trial Update: A Phase Ⅲ Study of Hemay022 in Combination With AI In Advanced Breast Cancer [Phase 3]

  Phase III clinical trial evaluating Hemay022 in combination with an aromatase inhibitor for advanced breast cancer is currently recruiting.

• CLINICAL_TRIALS research · 2025-04-22
  Clinical Trial Update: Clinical Efficacy and Safety Assessment of Breast-Conserving Surgery for Central Breast Cancer: A Prospective Randomized Controlled Trial [NA]

  This ClinicalTrials.gov entry outlines a prospective randomized controlled trial evaluating the efficacy and safety of breast-conserving sur…

• CLINICAL_TRIALS research · 2025-04-22
  Clinical Trial Update: Use of an Ultra-rapid BRCA1/2 Status Screening Test in Diagnostic and Theranostic Indication: Performance and Interest for Patients and Practitioners

  This clinical trial update discusses an ultra-rapid BRCA1/2 status screening test for diagnostic and theranostic use in breast cancer, evalu…

• CLINICAL_TRIALS research · 2025-04-22
  Clinical Trial Update: ICG vs Blue Patent for TAD in cN1 Breast Carcinoma After Neoadjuvant Chemotherapy

  A clinical trial comparing indocyanine green (ICG) versus patent blue dye for targeted axillary dissection in clinically node-positive breas…

• CLINICAL_TRIALS research · 2025-04-22
  Clinical Trial Update: Development and Application of Accurate Detection Technology Based on Multimodal Data of Breast Cancer Comobid Depression

  The trial from Xiangya Hospital aims to develop and apply accurate detection technology for breast cancer using multimodal data, with attent…

• CLINICAL_TRIALS research · 2025-04-22
  Clinical Trial Update: The RolE of Prolonged Nightly faSTing to Improve Sleep and cOgnition in bREast Cancer Survivors [NA]

  A clinical trial is evaluating whether prolonged nightly fasting can improve sleep quality and cognitive difficulties in breast cancer survi…

• CLINICAL_TRIALS research · 2025-04-22
  Clinical Trial Update: Feasibility and Tolerability of Transcranial Direct Current Stimulation With Concurrent Cognitive Training [NA]

  Clinical trial update on the feasibility and tolerability of transcranial direct current stimulation with concurrent cognitive training. The…

• CLINICAL_TRIALS research · 2025-04-20
  Clinical Trial Update: Question Prompt List in Breast Cancer Patients Planned for Neoadjuvant Chemotherapy [NA]

  A clinical trial in early-stage breast cancer planning neoadjuvant chemotherapy is updating its protocol with a Question Prompt List to assi…

• CLINICAL_TRIALS research · 2025-04-20
  Clinical Trial Update: Optimizing Extended Adjuvant Endocrine Therapy in Patients With Breast Cancer [Phase 3]

  A Phase 3 clinical trial evaluating strategies for optimizing extended adjuvant endocrine therapy in breast cancer is currently not yet recr…