Breast Cancer

• CLINICAL_TRIALS research · 2025-06-22
  Clinical Trial Update: Application of Targeted Axillary Lymph Node Resection in Axillary Surgery After Neoadjuvant Chemotherapy for Breast Cancer: an Open-label, Multicenter Study [NA]

  Open-label, multicenter trial evaluating targeted axillary lymph node resection in axillary surgery after neoadjuvant chemotherapy for breas…

• CLINICAL_TRIALS research · 2025-06-22
  Clinical Trial Update: Feasibility Study of Adjuvant Enzalutamide for the Treatment of Early Stage AR (+) Triple Negative Breast Cancer [Phase 2]

  A Phase 2 feasibility trial evaluating adjuvant enzalutamide for early-stage androgen receptor-positive triple-negative breast cancer; the s…

• CLINICAL_TRIALS research · 2025-06-22
  Clinical Trial Update: A Trial of HRS-6209 in Combination With Fulvestrant, Letrozole, HRS-8080, or HRS-1358 in Breast Cancer Patients [Phase 1, Phase 2]

  A phase 1/phase 2 clinical trial update describing a study of HRS-6209 in combination with fulvestrant, letrozole, HRS-8080, or HRS-1358 for…

• CLINICAL_TRIALS research · 2025-06-22
  Clinical Trial Update: RADIomics to Predict HER2 Status And T-DXd Efficacy in Metastatic Breast Cancer: the RADIOSPHER2 Study

  A clinical trial evaluating radiomic predictors of HER2 status and response to trastuzumab deruxtecan (T-DXd) in metastatic breast cancer, c…

• CLINICAL_TRIALS research · 2025-06-19
  Clinical Trial Update: Comparative Research on the Accuracy of Margin Interpretation in Breast-Conserving Surgery for Breast Cancer: Cell Microscopic Imaging and Standard Frozen Pathology [NA]

  This clinical trial update reports ongoing comparative research to evaluate the accuracy of margin interpretation in breast-conserving surge…

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• CLINICAL_TRIALS research · 2025-06-19
  Clinical Trial Update: Analysis of the Real-world Prescription Pattern of Palbociclib Combination Therapy With Aromatase Inhibitor as a First Line Therapy in Metastatic Breast Cancer Patients Using the National Health Insurance Claims Data in South Korea

  A completed real-world study analyzing palbociclib in combination with aromatase inhibitors as first-line therapy for metastatic breast canc…

• CLINICAL_TRIALS research · 2025-06-19
  Clinical Trial Update: A Phase III Study of ESG401 for Locally Advanced or Metastatic HR+/HER2- Breast Cancer [Phase 3]

  Phase III trial evaluating ESG401 for locally advanced or metastatic HR+/HER2- breast cancer; the study is currently recruiting.

• CLINICAL_TRIALS research · 2025-06-19
  Clinical Trial Update: An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2) [Phase 3]

  A Phase 3 recruitment update for CAMBRIA-2, a study of Camizestrant (AZD9833) as adjuvant endocrine therapy for ER+/HER2- early breast cance…

• CLINICAL_TRIALS research · 2025-06-19
  Clinical Trial Update: A Phase 2 Study of PCS6422 With Capecitabine in Patients With Advanced or Metastatic Breast Cancer [Phase 2]

  This document reports a phase 2 clinical trial evaluating PCS6422 in combination with capecitabine for advanced or metastatic breast cancer,…

• CLINICAL_TRIALS research · 2025-06-18
  Clinical Trial Update: Evaluation of Vaginal Microbiome as a Biomarker for the Improvement of Vaginal Health in Women With Breast Cancer, ARISE Study

  Clinical trial update for the ARISE study evaluating vaginal microbiome as a biomarker for vaginal health in women with breast cancer; the s…

• CLINICAL_TRIALS research · 2025-06-18
  Clinical Trial Update: Dietary and Exercise Interventions in Reducing Side Effects in Patients With Stage I-IIIa Breast Cancer Receiving Aromatase Inhibitors [NA]

  This clinical trial update describes dietary and exercise interventions aimed at reducing side effects in patients with stage I-IIIa breast …

• CLINICAL_TRIALS research · 2025-06-18
  Clinical Trial Update: Correlation of Molecular Markers With Response to Therapy and Breast Cancer Behavior

  This clinical trial investigates how molecular markers relate to response to therapy and the behavior of breast cancer; the study is current…

• CLINICAL_TRIALS research · 2025-06-17
  Clinical Trial Update: The Exploration of Novel Radionuclide-labeled HER2-targeting Antibodies in the Diagnosis of HER2-positive Malignancies [EARLY_Phase 1]

  An early-phase 1 trial evaluating a radionuclide-labeled HER2-targeting antibody for diagnostic use in HER2-positive cancers, with enrollmen…

• CLINICAL_TRIALS research · 2025-06-17
  Clinical Trial Update: Application of 68GA-labeled CD73 Targeting Probe PET/CT Imaging in the Diagnosis of Breast Cancer [EARLY_Phase 1]

  An EARLY Phase 1 trial is evaluating a Gallium-68 labeled CD73-targeting PET/CT imaging probe for diagnosing breast cancer, currently recrui…

• CLINICAL_TRIALS research · 2025-06-17
  Clinical Trial Update: PET Image Exploration of 89Zr-labeled Antibody Fragments Targeting HER2 in Patients With Malignant Tumors [EARLY_Phase 1]

  Early-phase PET imaging study evaluating 89Zr-labeled antibody fragments targeting HER2 in patients with malignant tumors to assess uptake a…

• CLINICAL_TRIALS research · 2025-06-17
  Clinical Trial Update: Preoperative Nicotine Cessation for Women With Breast Cancer Recommended for Reconstruction [NA]

  A clinical trial evaluating preoperative nicotine cessation in women with breast cancer who are recommended for reconstruction; currently re…

• CLINICAL_TRIALS research · 2025-06-15
  Clinical Trial Update: A Phase II Study of HLX22 in Combination With Trastuzumab Deruxtecan in HER2-low, Hormone Receptor Positive Locally Advanced or Metastatic Breast Cancer Patients [Phase 2]

  A Phase II clinical trial is evaluating HLX22 in combination with trastuzumab deruxtecan for HER2-low, hormone receptor-positive breast canc…

• CLINICAL_TRIALS research · 2025-06-15
  Clinical Trial Update: Concomitant Radiotherapy and New Drugs in Metastatic Breast Cancer

  ClinicalTrials.gov update indicates a study on combining radiotherapy with new drugs for metastatic breast cancer is currently recruiting.

• CLINICAL_TRIALS research · 2025-06-15
  Clinical Trial Update: Financial Toxicity in Breast Cancer Surgery

  This entry notes a clinical trial at McMaster University investigating financial toxicity in breast cancer surgery. The trial is currently a…

• CLINICAL_TRIALS research · 2025-06-15
  Clinical Trial Update: Dose Escalated Concomitant Boost Radiotherapy for Early Breast Cancer [NA]

  This clinical trial update indicates a dose-escalation concomitant boost radiotherapy study for early breast cancer is currently recruiting.

• CLINICAL_TRIALS research · 2025-06-15
  Clinical Trial Update: Real Time Molecular Analysis of Breast Cancer Receiving Neo-adjuvant Chemotherapy

  This clinical trial is investigating real-time molecular analysis of breast cancer in patients receiving neoadjuvant chemotherapy and is cur…

• CLINICAL_TRIALS research · 2025-06-15
  Clinical Trial Update: Identification and Evaluation of Patients at Risk of Developing Cardiotoxicity After Receiving Chemotherapy for Breast Cancer, Lymphoma or Leukemia

  Clinical trial update from the Montreal Heart Institute describing efforts to identify and evaluate patients at risk of developing chemother…

• CLINICAL_TRIALS research · 2025-06-13
  Clinical Trial Update: Comparing UTD2 Combined With Capecitabine to Capecitabine as Adjuvant Therapy for Non-pCR TNBC Patients [Phase 3]

  Phase 3 clinical trial comparing UTD2 plus capecitabine to capecitabine alone as adjuvant therapy for patients with non-pCR triple-negative …

• CLINICAL_TRIALS research · 2025-06-13
  Clinical Trial Update: Vocational Rehabilitation for the Return to Work of Breast Cancer Patients: a Feasibility Study [NA]

  A feasibility study evaluating whether vocational rehabilitation can support breast cancer patients in returning to work.

• CLINICAL_TRIALS research · 2025-06-13
  Clinical Trial Update: Ketorolac and Pregabalin Effects on breaSt Cancer (KePreSt) [Phase 2]

  Phase 2 clinical trial update (KePreSt) assessing the effects of ketorolac and pregabalin in early-stage, estrogen receptor-positive breast …