Breast Cancer

• CLINICAL_TRIALS research · 2025-08-13
  Clinical Trial Update: Discontinuation of Maintenance HER-2 Directed Therapy in Long-Term Survivors of Metastatic HER-2 Positive Breast Cancer [NA]

  A clinical trial (NCT05959291) sponsored by the University of Miami is evaluating discontinuation of maintenance HER-2 directed therapy in l…

• CLINICAL_TRIALS research · 2025-08-13
  Clinical Trial Update: Evaluation of Cognitive Management for Chemobrain in Patients Treated for Breast Cancer. [NA]

  Clinical trial update from Institut Bergonié evaluating cognitive management strategies for chemotherapy-related cognitive impairment in bre…

• CLINICAL_TRIALS research · 2025-08-13
  Clinical Trial Update: Impact of Intermittent Fasting on Biomarkers of Inflammation and Health-Related Quality of Life: A Feasibility Trial for Women With HR+/HER2- Early Breast Cancer [NA]

  Feasibility trial evaluating intermittent fasting's impact on inflammation biomarkers and health-related quality of life in women with hormo…

• CLINICAL_TRIALS research · 2025-08-13
  Clinical Trial Update: Study of Molecular Characterisation of Early Operable Primary Breast Cancer in Pakistani Population

  This study aims to molecularly characterize early operable primary breast cancer in the Pakistani population and is currently recruiting.

• CLINICAL_TRIALS research · 2025-08-12
  Clinical Trial Update: A Phase I Study of [68Ga]Ga-DWJ155 in Patients With Breast and Lung Cancers [Phase 1]

  Phase I clinical trial update for the radiopharmaceutical [68Ga]Ga-DWJ155 in patients with breast cancer and non-small cell lung cancer; the…

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• CLINICAL_TRIALS research · 2025-08-12
  Clinical Trial Update: Determining the Biodistribution of an Imaging Tracer (68Ga-FAPi-46) in Patients With Solid Tumors or Hematologic Cancers [Phase 1]

  Phase 1 clinical trial examining the biodistribution of the Ga-68 labeled imaging tracer 68Ga-FAPi-46 in patients with solid tumors and hema…

• CLINICAL_TRIALS research · 2025-08-12
  Clinical Trial Update: A Novel Patient Decision Aid for Surgical Treatment Options in Early-Stage Breast Cancer [NA]

  This clinical trial update describes the development of a novel patient decision aid to help patients choose surgical treatment options for …

• CLINICAL_TRIALS research · 2025-08-12
  Clinical Trial Update: Exploration of the Safety and Efficacy of T-DXd Concurrent With Brain Radiotherapy in Patients With Brain Metastases HER2-positive/HER2-low Advanced Breast Cancer [NA]

  A clinical trial is exploring the safety and efficacy of trastuzumab deruxtecan (T-DXd) given concurrently with brain radiotherapy in patien…

• CLINICAL_TRIALS research · 2025-08-12
  Clinical Trial Update: Experimental PET Imaging Scans Before Cancer Surgery to Study the Amount of PET Tracer Accumulated in Normal and Cancer Tissues [EARLY_Phase 1]

  An early-phase 1 trial is investigating experimental PET imaging scans performed before cancer surgery to assess tracer uptake in normal and…

• CLINICAL_TRIALS research · 2025-08-12
  Clinical Trial Update: Tablet-based Mobile Health Ultrasound for Point-of-care Breast Cancer Diagnosis in Nigeria [NA]

  Memorial Sloan Kettering Cancer Center is conducting a clinical trial in Nigeria to evaluate tablet-based mobile health ultrasound for point…

• CLINICAL_TRIALS research · 2025-08-12
  Clinical Trial Update: HB1801 Combined Treatment of HER2-positive Breast Cancer [Phase 2]

  HB1801 is a Phase 2 study evaluating a combined treatment for HER2-positive breast cancer, with the trial currently not recruiting.

• CLINICAL_TRIALS research · 2025-08-12
  Clinical Trial Update: Patient Priorities for Survivorship Care in Older Breast Cancer Survivors [Phase 2]

  This Phase 2 clinical trial from UTHealth Houston is exploring patient priorities for survivorship care in older breast cancer survivors and…

• CLINICAL_TRIALS research · 2025-08-11
  Clinical Trial Update: PHOENIX DDR/Anti-PD-L1 Trial: A Pre-surgical Window of Opportunity and Post-surgical Adjuvant Biomarker Study of DNA Damage Response Inhibition With or Without Anti-PD-L1 Immunotherapy in Patients With Neoadjuvant Treatment Resistant Residual Triple Negative Breast Cancer [Phase 2]

  Phase 2 clinical trial evaluating a DNA damage response inhibitor with or without anti-PD-L1 immunotherapy in patients with neoadjuvant-trea…

• CLINICAL_TRIALS research · 2025-08-11
  Clinical Trial Update: Comparing Patient Reported Outcomes and Clinical Outcomes Based on Different Scar Placement in Patients Undergoing Standard Breast Conserving Surgery for Breast Cancer: The PROM-S Study.

  A clinical trial entry (NCT07116642) from The Leeds Teaching Hospitals NHS Trust studying patient-reported and clinical outcomes for differe…

• CLINICAL_TRIALS research · 2025-08-11
  Clinical Trial Update: 'ADVANCE' (A Pilot Trial) [Phase 1]

  The document notes a Phase 1 pilot trial called ADVANCE for breast cancer that is currently active but not recruiting. It is sponsored by th…

• CLINICAL_TRIALS research · 2025-08-11
  Clinical Trial Update: Trastuzumab Rezetecan Combined With Radiotherapy Versus Trastuzumab Rezetecan in the Treatment of HER2-positive Advanced Breast Cancer With Brain Metastases [Phase 2]

  This Phase 2 clinical trial is comparing trastuzumab rezetecan with radiotherapy versus trastuzumab rezetecan alone in patients with HER2-po…

• CLINICAL_TRIALS research · 2025-08-11
  Clinical Trial Update: Molecular Breast Imaging (MBI)-Guided Biopsy [NA]

  A clinical trial update for a not-yet-recruiting study evaluating Molecular Breast Imaging-guided biopsy for breast cancer detection in dens…

• CLINICAL_TRIALS research · 2025-08-11
  Clinical Trial Update: QL1706 With Olaparib for Previously Treated HER2-negative Breast Cancer Patients With Homologous Recombination Deficiency (HRD) [Phase 2]

  A Phase 2 trial of QL1706 in combination with Olaparib for previously treated HER2-negative breast cancer patients with homologous recombina…

• CLINICAL_TRIALS research · 2025-08-08
  Clinical Trial Update: Establishment of Molecular Profiling for Individual Clinical Routine Treatment Decision in Early Breast Cancer

  Clinical trial update describes establishing molecular profiling to guide individual treatment decisions in early breast cancer. The study i…

• CLINICAL_TRIALS research · 2025-08-08
  Clinical Trial Update: Role of FGF21 in Breast Cancer

  A clinical trial is evaluating the role of fibroblast growth factor 21 (FGF21) in breast cancer, with the study currently not recruiting.

• CLINICAL_TRIALS research · 2025-08-07
  Clinical Trial Update: SKB264 Combined With KL-A167 Neoadjuvant Therapy for Early-stage, High-risk ER+/HER2- Breast Cancer [Phase 2]

  A Phase 2 trial evaluating SKB264 in combination with KL-A167 as neoadjuvant therapy for early-stage, high-risk ER+/HER2- breast cancer; the…

• CLINICAL_TRIALS research · 2025-08-07
  Clinical Trial Update: A Novel Surgical Irrigation Solution in Post-Mastectomy Reconstruction: Evaluating Xperience™ [NA]

  Trial update on Xperience™, a novel surgical irrigation solution, evaluating its use in post-mastectomy reconstruction to reduce surgical si…

• CLINICAL_TRIALS research · 2025-08-07
  Clinical Trial Update: Evaluation of Talazoparib, a PARP Inhibitor, in Patients With Somatic BRCA Mutant Metastatic Breast Cancer: Genotyping Based Clinical Trial [Phase 2]

  Phase 2 genotyping-based trial evaluating talazoparib in patients with somatic BRCA-mutant metastatic breast cancer; currently recruiting.

• CLINICAL_TRIALS research · 2025-08-07
  Clinical Trial Update: Psychological Distress in Breast Cancer Patients: A Cross-Sectional Study in Iraq

  A completed cross-sectional study conducted in Iraq examines psychological distress in breast cancer patients. The study reports on prevalen…

• CLINICAL_TRIALS research · 2025-08-07
  Clinical Trial Update: ESPB Versus Perioperative Iv Lidocaine Infusion on Proinflammatory Cytokines in Breast Cancer Surgeries [NA]

  This trial compares erector spinae plane block (ESPB) versus perioperative intravenous lidocaine infusion in breast cancer surgery to assess…