Breast Cancer

• CLINICAL_TRIALS research · 2026-02-09
  Clinical Trial Update: Cardiotoxicity of Cancer Therapy (CCT)

  The Cardiotoxicity of Cancer Therapy (CCT) trial, sponsored by the Abramson Cancer Center at Penn Medicine, is enrolling by invitation in br…

• CLINICAL_TRIALS research · 2026-02-09
  Clinical Trial Update: Study on the Treatment of HER2-negative Breast Cancer Brain Metastases With Radiotherapy Combined With Anlotinib [Phase 2]

  Phase 2 clinical trial evaluating radiotherapy combined with Anlotinib for HER2-negative breast cancer with brain metastases; currently recr…

• CLINICAL_TRIALS research · 2026-02-09
  Clinical Trial Update: Pregnancy Outcome and Safety of Interrupting Therapy for Women With Endocrine Responsive Breast Cancer [NA]

  This clinical trials update describes pregnancy outcomes and the safety of interrupting endocrine therapy for women with endocrine-responsiv…

• CLINICAL_TRIALS research · 2026-02-09
  Clinical Trial Update: Virtual Mindful After Cancer (MAC) Intervention to Promote Sexual Health for Breast and Gynecologic Cancer Survivors [Phase 1]

  A Phase 1 clinical trial evaluating a virtual mindfulness-based intervention called Mindful After Cancer (MAC) to promote sexual health in b…

• CLINICAL_TRIALS research · 2026-02-09
  Clinical Trial Update: Radiation Therapy Followed by Intrathecal Trastuzumab/Pertuzumab in HER2+ Breast Leptomeningeal Disease [Phase 1, Phase 2]

  This is an early-phase trial evaluating radiation therapy followed by intrathecal trastuzumab and pertuzumab for HER2-positive breast cancer…

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• CLINICAL_TRIALS research · 2026-02-09
  Clinical Trial Update: A Phase 1-2 Study of ST101 in Patients With Advanced Solid Tumors [Phase 1, Phase 2]

  Phase 1-2 study of ST101 in patients with advanced solid tumors, including glioblastoma and melanoma. The trial is currently active but not …

• CLINICAL_TRIALS research · 2026-02-09
  Clinical Trial Update: Elacestrant and Exemestane for Patients With Pretreated HR+/HER2- Metastatic Breast Cancer and [18F] FES-avid Lesions (COMBINE) [Phase 2]

  Phase 2 trial evaluating the combination of elacestrant and exemestane in pretreated HR+/HER2- metastatic breast cancer; the study is not ye…

• CLINICAL_TRIALS research · 2026-02-09
  Clinical Trial Update: Study of Screening Brain MRIs in Stage IV Breast Cancer

  A clinical trial at H. Lee Moffitt Cancer Center is evaluating the use of screening brain MRIs in patients with Stage IV breast cancer, incl…

• CLINICAL_TRIALS research · 2026-02-06
  Clinical Trial Update: A Randomized Two-Arm Proof of Concept Study Testing A Novel Approach to Exercise Promotion Based on Affect-regulation [NA]

  A randomized two-arm proof-of-concept clinical trial evaluating a novel affect-regulation-based approach to promoting exercise in breast can…

• CLINICAL_TRIALS research · 2026-02-06
  Clinical Trial Update: BreastCancerPEP: A Six-Month Online Empowerment Program to Improve Mental and Physical Health in Women With Breast Cancer [NA]

  This clinical trial entry describes an online six-month empowerment program for women with breast cancer, aimed at improving mental and phys…

• CLINICAL_TRIALS research · 2026-02-06
  Clinical Trial Update: Neoadjuvant Trastuzumab Deruxtecan (SHR-A1811) + Pertuzumab in HER2+ Breast Cancer [Phase 2]

  This document notes a Phase 2 neoadjuvant trial investigating trastuzumab deruxtecan (SHR-A1811) in combination with pertuzumab for HER2-pos…

• CLINICAL_TRIALS research · 2026-02-06
  Clinical Trial Update: Stereotactic Radiation & Abemaciclib in the Management of HR+/HER2- Breast Cancer Brain Metastases [Phase 1, Phase 2]

  A Phase 1/2 trial evaluating the combination of stereotactic radiation and abemaciclib for HR-positive, HER2-negative metastatic breast canc…

• CLINICAL_TRIALS research · 2026-02-06
  Clinical Trial Update: Prospective Study of the Prosigna Assay on Neoadjuvant Clinical Decision-making in Women With HR+/Her2- Breast Cancer

  Prospective study evaluating the Prosigna genomic assay for informing neoadjuvant treatment decisions in women with HR+/HER2- breast cancer;…

• CLINICAL_TRIALS research · 2026-02-06
  Clinical Trial Update: Breast Fractionation Study - Standard Versus Investigational Fractionation Trial - Nodal Radiation [NA]

  A status update for a breast cancer trial comparing standard versus investigational nodal radiation fractionation in post-mastectomy patient…

• CLINICAL_TRIALS research · 2026-02-06
  Clinical Trial Update: Primary Breast Oligoprogressive Sites Treated With Radiotherapy to Obviate the Need to Change Systemic Therapy [NA]

  A Mayo Clinic-backed clinical trial is evaluating the use of radiotherapy on oligoprogressive sites in metastatic breast cancer to avoid swi…

• CLINICAL_TRIALS research · 2026-02-06
  Clinical Trial Update: DiviTum®TKa: A Biomarker Assay for Efficacy in HR+ Metastatic Breast Cancer Patients

  DiviTum TKa is being evaluated as a biomarker assay in a clinical trial for efficacy in HR-positive, HER2-negative metastatic breast cancer;…

• CLINICAL_TRIALS research · 2026-02-06
  Clinical Trial Update: ctDNA-guided Treatment Decision-making [Phase 2]

  Phase 2 clinical trial evaluating ctDNA-guided treatment decision-making in metastatic HER2-negative breast cancer; currently recruiting.

• CLINICAL_TRIALS research · 2026-02-06
  Clinical Trial Update: A Phase III Clinical Trial of NTQ1062 in Combination With Fulvestrant for the Treatment of Advanced or Metastatic HR+/HER2- Breast Cancer [Phase 3]

  A Phase III trial evaluating NTQ1062 in combination with Fulvestrant for advanced or metastatic hormone receptor-positive/HER2-negative brea…

• CLINICAL_TRIALS research · 2026-02-06
  Clinical Trial Update: Researching the Effect of Exercise on Cancer [NA]

  This update notes an active-not-recruiting clinical trial from Memorial Sloan Kettering Cancer Center investigating the effects of exercise …

• CLINICAL_TRIALS research · 2026-02-06
  Clinical Trial Update: A Study of Breast Cancer Risk Factors and Outcomes of People in Florida

  This clinical trial update notes a Memorial Sloan Kettering Cancer Center study in Florida assessing breast cancer risk factors and outcomes…

• CLINICAL_TRIALS research · 2026-02-05
  Clinical Trial Update: Telehealth Exercise Program Evaluating Fatigue and Physical Function in Rural Cancer Survivors [Phase 2]

  A Phase 2 trial from the University of Colorado Denver is testing a telehealth exercise program to reduce cancer-related fatigue and improve…

• CLINICAL_TRIALS research · 2026-02-05
  Clinical Trial Update: A Study of SH009 Injection in Patients With Advanced Solid Tumors. [Phase 1]

  A Phase 1 clinical trial update for SH009 Injection in patients with advanced solid tumors, currently recruiting across multiple indications…

• CLINICAL_TRIALS research · 2026-02-05
  Clinical Trial Update: Evaluation of PSMA in HER2- AR+ Metastatic Breast Cancer [Phase 2]

  Phase 2 clinical trial evaluating a PSMA-targeted approach in HER2-negative, AR-positive metastatic breast cancer, currently recruiting.

• CLINICAL_TRIALS research · 2026-02-05
  Clinical Trial Update: B-GLUCANCER2 : A Pilot Study Evaluating a New Method for Cancer Detection by Measuring the Activity of Different Glycosidase Enzymes in the Plasma of Patients With a Localized Cancer. [EARLY_Phase 1]

  An early-phase clinical trial update for B-GLUCANCER2, a pilot study that assesses a blood-based detection method by measuring glycosidase e…

• CLINICAL_TRIALS research · 2026-02-05
  Clinical Trial Update: Prevention of Postoperative Complications by Negative Pressure Therapy After Complex Breast Cancer Surgery [NA]

  A clinical trial is investigating whether negative pressure therapy after complex breast cancer surgery reduces postoperative complications;…