Breast Cancer
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Breast Cancer Organelle Properties and Protein Expression Atlas in the Three Immunohistochemical Subtypes of Breast Cancers [NA]
Clinical trial investigating organelle properties and protein expression across the three immunohistochemical subtypes of breast cancer, enr…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: CDK4/6 Inhibitors in Breast Cancer Elderly Patients: an Observational Ambispective Longitudinal Multicenter Study
An observational ambispective longitudinal multicenter study evaluating CDK4/6 inhibitors for breast cancer in elderly patients, currently r…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: A Prospective Study of Video-assisted Exercise Program for the Breast Cancer Survivors [NA]
Prospective study evaluating a video-assisted exercise program for breast cancer survivors (mastectomy), currently recruiting.
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Pilot Breast-Dedicated PET Camera With 1 Millimeter Spatial Resolution [EARLY_Phase 1]
This document provides an early-phase update on a pilot breast-dedicated PET camera with 1 mm spatial resolution, sponsored by Stanford Univ…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Gedatolisib Plus Fulvestrant With or Without Palbociclib vs Standard-of-Care for the Treatment of Patients With Advanced or Metastatic HR+/HER2- Breast Cancer (VIKTORIA-1) [Phase 3]
A Phase 3 clinical trial update indicates Gedatolisib plus Fulvestrant, with or without Palbociclib, is active but not recruiting for advanc…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Conformal Ablative Radiotherapy in Older Women (CARMEN) With Breast Cancer Undergoing Non-Operative Management [NA]
The CARMEN trial is currently recruiting older women with breast cancer undergoing non-operative management to evaluate conformal ablative r…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: TACTIVE-U: A Study to Learn About the Study Medicine (Vepdegestrant) When Given With Other Medicines in People With Advanced or Metastatic Breast Cancer (Sub-Study A) [Phase 1, Phase 2]
An early-phase (Phase 1/2) clinical trial evaluating vepdegestrant in combination with other medicines for advanced or metastatic breast can…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: A Study to Compare the Steady-State Bioavailability of Injectable Letrozole SIE and Oral Letrozole in Post-Menopausal Women With Hormone Receptor Positive Early Breast Cancer [Phase 1]
Phase 1 study comparing steady-state bioavailability of injectable Letrozole SIE versus oral Letrozole in postmenopausal women with hormone …
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: FLASH-Breast: Evaluating the Efficacy of Fezolinetant in Reducing Vasomotor Symptoms in Women With Breast Cancer on Endocrine Therapy [Phase 2]
A Phase 2 clinical trial (FLASH-Breast) is evaluating fezolinetant to reduce vasomotor symptoms in women with breast cancer on endocrine the…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Efficacy and Safety of Extended-Dose Interval Immunotherapy Versus Standard-Dose Interval Immunotherapy for Advanced Triple-Negative Breast Cancer [Phase 2]
A Phase 2 clinical trial is evaluating whether extended-dose interval immunotherapy provides similar or better efficacy and safety compared …
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: A Study Comparing the Efficacy and Safety of Zanidatamab to Trastuzumab, Each in Combination With Physician's Choice Chemotherapy, for the Treatment of Participants With Metastatic HER2-positive Breast Cancer [Phase 3]
A Phase 3 study evaluating zanidatamab plus physician's choice chemotherapy versus trastuzumab plus chemotherapy in metastatic HER2-positive…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Real-World Treatment Patterns and Outcomes in HER2-Altered Metastatic Breast Cancer Patients in the United States
Real-world study in the United States evaluating treatment patterns and outcomes for patients with HER2-altered metastatic breast cancer; th…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: A Phase I/II Study of FWD1802 in Patients With ER+/HER2- Advanced BC. [Phase 1, Phase 2]
Forward Pharmaceuticals is conducting a Phase I/II trial of FWD1802 in patients with ER+/HER2- advanced breast cancer (metastatic or locally…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Rhomboid Intercostal Sub-serratus Plane Blocks and Erector Spinae Plane Block in Mastectomy Surgeries [NA]
A clinical trial in Egypt is evaluating rhomboid intercostal sub-serratus plane blocks and erector spinae plane blocks for mastectomy anesth…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Breast Cancer Resiliency Through Exercise Program (B-REP) [NA]
A University of Michigan clinical trial called Breast Cancer Resiliency Through Exercise Program (B-REP) is currently recruiting participant…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: TRPC6 Characterization to Predict and Prevent Chemotherapy Related Cardiomyopathy and Heart Failure With Breast Cancer
A Mayo Clinic-sponsored clinical trial seeks to characterize TRPC6 to predict and prevent chemotherapy-related cardiomyopathy and heart fail…
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: P-MUC1C-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With Advanced or Metastatic Solid Tumors [Phase 1]
Phase 1 trial update of P-MUC1C-ALLO1, an allogeneic CAR-T cell therapy, being studied in advanced or metastatic solid tumors. The study is …
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: Evaluating Omission of Granulocyte Colony-stimulating Factors in Breast Cancer Patients Receiving Paclitaxel Portion of Dose-dense Adriamycin-cyclophosphamide and Paclitaxel Chemotherapy [Phase 4]
This Phase 4 clinical trial from the Ottawa Hospital Research Institute is evaluating whether granulocyte colony-stimulating factor (G-CSF) …
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: CIPHER Study: Pilot Study to Study the Role of ctDNA in Triple Negative and HER2 Positive Early Stage [EARLY_Phase 1]
A pilot Phase 1 study at Rutgers is evaluating circulating tumor DNA as a biomarker in early-stage triple-negative and HER2-positive breast …
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: Asian Study of Sacituzumab Govitecan (IMMU-132) in HR+/HER2- Metastatic Breast Cancer (MBC) [Phase 3]
This update describes an Asian Phase 3 trial evaluating Sacituzumab Govitecan (IMMU-132) for HR+/HER2- metastatic breast cancer, with the st…
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: Dissemination of BREASTChoice AIM1-B [NA]
This clinical trial update indicates that recruitment is ongoing for the BREASTChoice AIM1-B study related to breast cancer, disseminated by…
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: Effects of Immune Checkpoint Inhibitors on Coronary Microvasculature
A clinical trial at Abramson Cancer Center investigates the effects of immune checkpoint inhibitors on the coronary microvasculature, with a…
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: Responses to Genetic Risk Modifier Testing Among Women With BRCA1/2 Mutations
This clinical trial update describes a study evaluating responses to genetic risk modifier testing in women with BRCA1/2 mutations; the stud…
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: Evaluating Dose Timing (Morning vs Evening) of Endocrine-based Therapies in Metastatic Breast and Prostate Cancers [Phase 4]
This Phase 4 study investigates whether morning versus evening dosing of endocrine-based therapies improves outcomes in metastatic breast ca…
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CLINICAL_TRIALS research · 2026-02-09Clinical Trial Update: Pilot Observational Study of an Integrative Cure Stay Program
This document reports a pilot observational study at University Hospital Basel evaluating an integrative 'Cure Stay' program for patients wi…