Breast Cancer

• CLINICAL_TRIALS research · 2026-02-20
  Clinical Trial Update: Trastuzumab Deruxtecan (T-DXd) With or Without Pertuzumab Versus Taxane, Trastuzumab and Pertuzumab in HER2-positive Metastatic Breast Cancer (DESTINY-Breast09) [Phase 3]

  This Phase 3 trial DESTINY-Breast09 is evaluating trastuzumab deruxtecan with or without pertuzumab versus a taxane-based regimen plus trast…

• CLINICAL_TRIALS research · 2026-02-20
  Clinical Trial Update: Auricular Acupressure for Perioperative Anxiety and Pain in Therapeutic Breast Surgery (ROSA) [NA]

  Clinical trial update on auricular acupressure to reduce perioperative anxiety and pain in women undergoing therapeutic breast surgery; recr…

• CLINICAL_TRIALS research · 2026-02-20
  Clinical Trial Update: FDG-PET/CT vs. CT for Monitoring Metastatic Breast Cancer [NA]

  A clinical trial is evaluating FDG-PET/CT versus conventional CT for monitoring metastatic breast cancer. The study is currently recruiting.

• CLINICAL_TRIALS research · 2026-02-20
  Clinical Trial Update: Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid Tumors

  Clinical trial evaluating circulating tumor DNA as an early biomarker to assess treatment response across multiple solid tumors; currently r…

• CLINICAL_TRIALS research · 2026-02-20
  Clinical Trial Update: Onco-primary Care Networking to Support TEAM-based Care [NA]

  Clinical trial update noting that the Duke University study on oncology-primary care networking to support TEAM-based care is currently ACTI…

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• CLINICAL_TRIALS research · 2026-02-20
  Clinical Trial Update: Oncology Episode Payment Model in Hawaii [NA]

  An update on an oncology episode payment model trial in Hawaii sponsored by the University of Pennsylvania. The study covers breast cancer, …

• CLINICAL_TRIALS research · 2026-02-20
  Clinical Trial Update: Sexual Functıon in Young Women After Breast Cancer Surgery

  This entry reports a clinical trial recruiting young adult women after breast cancer surgery to evaluate sexual function outcomes.

• CLINICAL_TRIALS research · 2026-02-20
  Clinical Trial Update: The Florida ASCENT Study [NA]

  The Florida ASCENT Study, sponsored by the University of Florida, is currently recruiting and investigates cancer outcomes in the context of…

• CLINICAL_TRIALS research · 2026-02-20
  Clinical Trial Update: Three Fraction Radiation to Induce Immuno-Oncologic Response [NA]

  Clinical trial update on using three fractions of radiation to induce an immuno-oncologic response in locally advanced breast cancer; the st…

• CLINICAL_TRIALS research · 2026-02-20
  Clinical Trial Update: Abbreviated MBCT for Depression in Older African American/Black Breast Cancer Survivors [NA]

  This entry reports an active, non-recruiting clinical trial evaluating abbreviated MBCT to treat depression in older African American/Black …

• CLINICAL_TRIALS research · 2026-02-20
  Clinical Trial Update: Study Evaluating DNA Double-strand Breaks (DSBs) REpair Factors (POLQ, Shieldin Complex and 53BP1) Expression as Biomarker of PARP Inhibitor Resistance in Patients With Deleterious Germline Mutation in BRCA 1/2 and HER2-negative, Metastatic or Locally Advanced Breast Cancer. [NA]

  This clinical trial is investigating expression of DNA double-strand break repair factors (POLQ, Shieldin complex, and 53BP1) as biomarkers …

• CLINICAL_TRIALS research · 2026-02-19
  Clinical Trial Update: Study of AZD5305 as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Malignancies [Phase 1, Phase 2]

  AZD5305 is being evaluated as a monotherapy and in combination with anti-cancer agents in a Phase 1/2 trial for multiple advanced solid mali…

• CLINICAL_TRIALS research · 2026-02-19
  Clinical Trial Update: HER2 Molecular Imaging With 89Zr-trastuzumab PET/CT as a Predictive Biomarker for Antibody-drug Conjugate Sequencing in Patients With Advanced HER2-positive Breast Cancer [Phase 2]

  A Phase 2 clinical study is evaluating 89Zr-trastuzumab PET/CT imaging as a predictive biomarker to help sequence antibody-drug conjugates i…

• CLINICAL_TRIALS research · 2026-02-19
  Clinical Trial Update: Ultrasound Guided Pecs Block and Ketamine Infusion for Preventing Chronic Pain in Patients Undergoing Breast Cancer Surgery [NA]

  This clinical trial will evaluate whether an ultrasound-guided Pecs block with ketamine infusion can reduce chronic pain after breast cancer…

• CLINICAL_TRIALS research · 2026-02-19
  Clinical Trial Update: Geriatric Care Survivorship Intervention for Improving the Overall Health of Older Adults With Stage I-III Breast Cancer Who Have Completed Curative Treatment [NA]

  This ClinicalTrials.gov entry describes an ongoing geriatric survivorship intervention aimed at improving overall health in older adults wit…

• CLINICAL_TRIALS research · 2026-02-19
  Clinical Trial Update: Comparison of Breast Cancer Screening With CESM to DBT in Women With Dense Breasts [NA]

  A clinical trial comparing contrast-enhanced spectral mammography (CESM) to digital breast tomosynthesis (DBT) for breast cancer screening i…

• CLINICAL_TRIALS research · 2026-02-19
  Clinical Trial Update: Mammography, Early Detection Biomarkers, Risk Assessment, and Imaging Technologies, MERIT Study

  This clinical trial update describes the MERIT study, which evaluates mammography, early detection biomarkers, risk assessment, and imaging …

• CLINICAL_TRIALS research · 2026-02-19
  Clinical Trial Update: Correlation Between Tumor-infiltrating Lymphocytes and Response to Systemic Therapy in Breast Cancer

  A completed study from the Institute of Oncology Ljubljana examined whether tumor-infiltrating lymphocytes predict response to systemic ther…

• CLINICAL_TRIALS research · 2026-02-19
  Clinical Trial Update: A Platform Study Based on Specific Tracer for Evaluating the Therapeutic Efficacy of Systemic Treatment for Breast Cancer Using PET/MRI [Phase 2]

  A Phase 2 platform study at Fudan University is evaluating a tracer-based PET/MRI approach to assess the efficacy of systemic therapy for br…

• CLINICAL_TRIALS research · 2026-02-19
  Clinical Trial Update: Patient-Derived Breast Cancer Organoids for Therapeutic Extracellular Vesicle Isolation (PDO-Mercurial01)

  This entry reports on the PDO-Mercurial01 trial using patient-derived breast cancer organoids for therapeutic extracellular vesicle isolatio…

• CLINICAL_TRIALS research · 2026-02-19
  Clinical Trial Update: Axillary Node Dissection w or w/o LVB in Node Positive Breast Cancer Patients [NA]

  A clinical trial update describing a study of axillary lymph node dissection with or without lymphatic vessel bypass (LVB) in patients with …

• CLINICAL_TRIALS research · 2026-02-19
  Clinical Trial Update: A Study of Changes in Ki67 Expression in People With Breast Cancer Receiving Endocrine Therapy Before Surgery [NA]

  A clinical trial update studying changes in Ki67 expression in people with breast cancer receiving endocrine therapy before surgery; the stu…

• CLINICAL_TRIALS research · 2026-02-19
  Clinical Trial Update: Preoperative Shoulder Exercises and Postoperative Inflammation, Pain, and Function After Modified Radical Mastectomy [NA]

  Clinical trial update describing a preoperative shoulder exercise program and its potential impact on postoperative inflammation, pain, and …

• CLINICAL_TRIALS research · 2026-02-19
  Clinical Trial Update: Connecting Black Families in Houston, Texas to Hereditary Cancer Genetic Counseling, Genetic Testing, and Cascade Testing by Using a Simple Genetic Risk Screening Tool and Telegenetics [NA]

  This clinical trial update from MD Anderson Cancer Center describes a study to connect Black families in Houston to hereditary cancer geneti…

• CLINICAL_TRIALS research · 2026-02-19
  Clinical Trial Update: A Study of Tumor Imaging With Multispectral Optoacoustic Tomography

  This clinical trial update describes a study evaluating tumor imaging with Multispectral Optoacoustic Tomography (MSOT) at Memorial Sloan Ke…