Breast Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Screening Mammography: Single Reading by One Radiologist With AI vs. Double Reading by Two Radiologists (AI-BCSQ) [NA]
Clinical trial comparing single-reading by one radiologist with AI versus double-reading by two radiologists for breast cancer screening; cu…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Safety and Efficacy of T-DXd vs. CDK4/6i-based ET as First-line Therapy of HR-positive and HER2-low/Ultralow Advanced Breast Cancer Patients Classified as Non-luminal Subtype [Phase 2]
A Phase 2 trial comparing trastuzumab deruxtecan versus CDK4/6 inhibitor–based endocrine therapy as first-line treatment for HR-positive, HE…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Concurrent Neoadjuvant Chemo/Endocrine Therapy in HER2+ Breast Cancer [Phase 2]
Phase 2 trial exploring concurrent neoadjuvant chemotherapy and endocrine therapy for HER2-positive breast cancer; the study is currently no…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: S1703 Serum Tumor Marker Directed Disease Monitoring in Patients With Hormone Receptor Positive Her2 Negative Metastatic Breast Cancer [NA]
An ongoing SWOG trial (S1703) is evaluating serum tumor marker-directed disease monitoring in hormone receptor-positive, HER2-negative metas…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010) [Phase 3]
A Phase 3 study of Sacituzumab Tirumotecan (MK-2870) as a single agent and in combination with pembrolizumab (MK-3475) versus physician's ch…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Real-World Treatment Pattern and Clinical Outcome With Influential Factors of HR+/HER2-aBC 1L Patients in China
A registry-like real-world study in China evaluating first-line treatment patterns and outcomes for HR+/HER2- advanced or metastatic breast …
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Evaluating an Endocrine Therapy Dose-frequency Escalation Strategy and Its Effects on Tolerability and Compliance [Phase 4]
A Phase 4 clinical trial update describes evaluating a dose-frequency escalation strategy for an endocrine therapy in breast cancer and its …
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: FIH Study of RGT-419B Alone and With Endocrine Therapy in HR-Positive, HER2-Negative Advanced/Metastatic Breast Cancer [Phase 1]
Regor Pharmaceuticals is conducting a Phase 1 trial of RGT-419B alone and in combination with endocrine therapy for HR-positive, HER2-negati…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Stereotactic Ablative Body Radiotherapy (SABR) With Maintenance of Systemic Therapy Versus Physicians' Choice of Systemic Therapy for Oligoprogressive ER-positive, Her-2 Negative Breast Cancer II [NA]
A clinical trial evaluating stereotactic ablative body radiotherapy with maintenance systemic therapy versus physician's choice of systemic …
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: A First in Human Dose Escalation of Dendritic Cell Vaccine (DCV) [Phase 1]
First-in-human, dose-escalation Phase 1 study of a dendritic cell vaccine (DCV) is underway, with recruitment for leptomeningeal carcinomato…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Adoptive T Cell Therapy Following HER2-Pulsed Dendritic Cell Vaccine & Pepinemab /Trastuzumab in Patients w/ Metastatic HER2+ Breast Cancer [Phase 1]
Phase 1 clinical trial evaluating adoptive T cell therapy after a HER2-pulsed dendritic cell vaccine, in combination with pepinemab and tras…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Personalized Antiemetic Regimen According to Patients' Pharmacogenetic Profile [Phase 2]
Phase 2 trial evaluating a personalized antiemetic regimen guided by patients' pharmacogenetic profile in breast cancer.
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Clinical Breast Examination and Patient Navigation Intervention in Sub-Saharan Africa [NA]
This entry reports an active-but-not-recruiting clinical trial from Addis Ababa University evaluating clinical breast examination and patien…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Pharmacokinetic Model of Abemaciclib: Correlation With Severe Diarrhea as the Primary Toxicity Endpoint in Patients With Localized Hormone Receptor-positive Breast Cancer [Phase 4]
This Phase 4 study assesses the pharmacokinetic model of abemaciclib and its correlation with severe diarrhea as the primary toxicity endpoi…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: A Non-interventional Study for Kisqali (Ribociclib) in Combination With an Aromatase Inhibitor for Adjuvant Treatment in Patients With HR+/HER2- Early Breast Cancer at High Risk of Recurrence
This is a non-interventional study evaluating the use of ribociclib (Kisqali) in combination with an aromatase inhibitor as adjuvant therapy…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Standard Verbal Counseling With or Without a Pictorial Educational Tool for the Reduction of Psychological Morbidity in Patients With Stage 0-IIIA Breast Cancer Receiving Radiation Therapy, COPE Study [NA]
This clinical trial update describes a study evaluating standard verbal counseling with or without a pictorial educational tool to reduce ps…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Oral Paclitaxel Trial In Recurrent and Metastatic Breast Cancer As 1st Line Therapy [Phase 2, Phase 3]
An oral paclitaxel trial for first-line treatment of recurrent or metastatic breast cancer is in Phase 2/3 and currently not recruiting. Spo…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Collecting Patient-Reported Experiences With Radiation Dermatitis in Breast Cancer Patients Undergoing Radiotherapy
A Mayo Clinic-led clinical trial is collecting patient-reported experiences of radiation dermatitis in women with breast cancer undergoing r…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Phase II Study of Systemic Screening in Pathologic Node Positive Breast Cancer [Phase 2]
An ongoing Phase II clinical trial evaluating systemic screening in patients with pathologic node-positive breast cancer; the study is curre…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: A Patient Navigation Intervention for the Improvement of Risk Management Among Women at High Risk of Breast Cancer [NA]
This clinical trial update describes a patient navigation intervention designed to improve risk management for women at high risk of breast …
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Study of SHR-A1811 in HER2-expression Advanced Breast Cancer With Brain Metastases [Phase 2]
Phase 2 clinical trial evaluating SHR-A1811 in HER2-positive metastatic breast cancer with brain metastases; recruitment is ongoing. The stu…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Development and Usability Evaluation of a Knowledge Graph-Based Symptom Management System for Patients With Breast Cancer Undergoing Chemotherapy [NA]
This entry documents the development and usability evaluation of a knowledge graph–based symptom management system for patients with breast …
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Epidemiology and Treatment of HR+/HER2- Breast Cancer in England
A completed clinical trial update examining epidemiology and treatment patterns for HR+/HER2- breast cancer in England.
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: A Trial to Evaluate Efficacy and Safety of Ribociclib With Endocrine Therapy as Adjuvant Treatment in Patients With HR+/HER2- Early Breast Cancer [Phase 3]
A Phase 3 trial assessing the efficacy and safety of ribociclib in combination with endocrine therapy as adjuvant treatment for HR+/HER2- ea…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Personalized Dendritic Cell Vaccine Pilot for High Risk TNBC After Neoadjuvant Therapy [EARLY_Phase 1]
A personalized dendritic cell vaccine is being evaluated in an early-phase trial for high-risk triple-negative breast cancer after neoadjuva…