Bone Cancer
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CLINICAL_TRIALS trial_result · 2024-12-05Clinical Trial Update: Tranexamic Acid Use to Reduce Blood Transfusion in Pediatric Cancer Patients Undergoing Limb Salvage Procedure [Phase 3]
Phase 3 trial evaluating tranexamic acid to reduce blood transfusions in pediatric bone cancer patients undergoing limb salvage was terminat…
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CLINICAL_TRIALS trial_result · 2024-12-03Clinical Trial Update: Restoring Mobility: Roles of Percutaneous Consolidation for Pelvic Ring Bone Lesions
This clinical trial update reports on a completed study evaluating percutaneous consolidation for pelvic ring bone lesions with the goal of …
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CLINICAL_TRIALS trial_result · 2024-11-05Clinical Trial Update: Functional Outcomes and Quality of Life in Musculoskeletal Tumor Patients With Distal Femoral Megaprostheses
This clinical trial update reports the completion of a study evaluating functional outcomes and quality of life in patients with distal femo…
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CLINICAL_TRIALS trial_result · 2024-07-01Clinical Trial Update: Longevity, Functional Status and Quality of Life of the Compress® Compliant Pre-Stress System [NA]
Clinical trial NCT04740749 evaluating the Compress Compliant Pre-Stress System for malignant bone tumors was terminated, with the update foc…
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CLINICAL_TRIALS trial_result · 2024-06-12Clinical Trial Update: [68Ga]Ga-P15-041 PET/CT in Variety of Bone Tumors [EARLY_Phase 1]
An early-phase PET/CT tracer [68Ga]Ga-P15-041 is being evaluated in patients with bone cancer and bone metastases in an initial study.
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CLINICAL_TRIALS research · 2024-05-09Clinical Trial Update: Biomechanics of Metastatic Defects in Bone
This entry reports an active-not-recruiting clinical trial at Beth Israel Deaconess Medical Center investigating the biomechanics of metasta…
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CLINICAL_TRIALS trial_result · 2024-02-07Clinical Trial Update: 18F-sodium Fluoride (NaF) PET to Replace Bone Scintigraphy: Safety and Efficacy Assessment [Phase 3]
Phase 3 trial evaluating 18F-sodium fluoride PET as a replacement for bone scintigraphy, assessing safety and efficacy.
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CLINICAL_TRIALS trial_result · 2024-02-07Clinical Trial Update: Feasibility of Combined Focused Ultrasound and Radiotherapy Treatment in Patients With Painful Bone Metastasis [Phase 1, Phase 2]
A completed phase 1/2 study evaluating the feasibility of combining focused ultrasound with radiotherapy for painful bone metastases.
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CLINICAL_TRIALS trial_result · 2023-12-12Clinical Trial Update: Study to Evaluate the Safety and Activity (Including Distribution) of 177Lu-3BP-227 in Subjects With Solid Tumours Expressing Neurotensin Receptor Type 1. [Phase 1]
Phase 1 trial evaluating safety and activity of 177Lu-3BP-227 in solid tumours expressing neurotensin receptor type 1; study terminated with…
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CLINICAL_TRIALS trial_result · 2023-10-24Clinical Trial Update: Performance and Safety of Biology-Guided Radiotherapy Using the RefleXion Medical Radiotherapy System (BIOGUIDE-X) [NA]
Completed clinical trial evaluating performance and safety of biology-guided radiotherapy with the RefleXion Radiotherapy System (BIOGUIDE-X…
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CLINICAL_TRIALS trial_result · 2023-08-29Clinical Trial Update: Evaluating Stereotactic Body Radiation Therapy for Oligometastatic Disease of the Bone [Phase 2]
Phase 2 trial evaluating stereotactic body radiation therapy for oligometastatic disease of the bone; results were posted in 2023.
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CLINICAL_TRIALS trial_result · 2019-06-18Clinical Trial Update: Differentiation of Bone Sarcomas and Osteomyelitis With Ferumoxytol-Enhanced MRI [Phase 2]
Phase 2 clinical trial updating the use of ferumoxytol-enhanced MRI to differentiate bone sarcomas from osteomyelitis.
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CLINICAL_TRIALS trial_result · 2018-02-13Clinical Trial Update: Study Evaluating the Biologic Activity of Guanabenz in Bone Metastasis [NA]
Clinical trial evaluating Guanabenz's biological activity in bone metastasis has terminated with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2017-10-18Clinical Trial Update: Pilot Study of Stereotactic Ablation for Oligometastatic Breast Neoplasia in Combination With the Anti-PD-1 Antibody MK-3475 [Phase 1]
A Phase 1 pilot study evaluating stereotactic ablation in combination with pembrolizumab (MK-3475) for oligometastatic breast cancer has com…
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CLINICAL_TRIALS trial_result · 2017-08-16Clinical Trial Update: A Study to Assess the Efficacy of Intravenous Bondronat (Ibandronate) in Patients With Malignant and Painful Bone Disease [Phase 3]
A Phase 3 trial evaluating intravenous ibandronate (Bondronat) for malignant and painful bone disease has been terminated.
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CLINICAL_TRIALS withdrawal · 2017-06-26Clinical Trial Update: Lenvatinib and Capecitabine in Patients With Advanced Malignancies [Phase 1]
A Phase 1 study of lenvatinib in combination with capecitabine for patients with advanced cancers has been withdrawn.
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CLINICAL_TRIALS trial_result · 2017-06-14Clinical Trial Update: Sodium Fluoride PET/CT for the Evaluation of Skeletal Cancer [NA]
This clinical trial update indicates termination of a study evaluating sodium fluoride PET/CT for imaging bone cancer, with trial results po…
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CLINICAL_TRIALS research · 2017-05-01Clinical Trial Update: Kinematics of Knees of Patients With Tumor Around Knee After Microwave Ablation With Plate Internal Fixation [NA]
This clinical trial update examines knee joint kinematics in patients with tumors around the knee after microwave ablation with plate intern…
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CLINICAL_TRIALS research · 2017-04-24Clinical Trial Update: MR Imaging- Guided High Intensity Focused Ultrasound (HIFU) Therapy of Bone Metastases [NA]
This entry describes a clinical trial evaluating MR imaging-guided High Intensity Focused Ultrasound therapy for bone metastases, with the t…
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CLINICAL_TRIALS trial_result · 2017-02-02Clinical Trial Update: Cyclophosphamide, Doxorubicin, Vincristine w/ Irinotecan and Temozolomide in Ewings Sarcoma [Phase 2]
A Phase 2 trial evaluating a multi-agent regimen of cyclophosphamide, doxorubicin, vincristine with irinotecan and temozolomide in Ewing sar…
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CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: A Study of Ibandronate (Bondronat) in Participants With Malignant Bone Disease [Phase 3]
Phase 3 study evaluating ibandronate (Bondronat) in participants with malignant bone disease has completed.
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CLINICAL_TRIALS trial_result · 2016-09-20Clinical Trial Update: Postoperative Bleeding Prevention in Massive Bone Tumour Resection [Phase 3]
Phase 3 trial evaluating postoperative bleeding prevention in massive bone tumor resections has been terminated. The update confirms the stu…
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CLINICAL_TRIALS trial_result · 2016-09-19Clinical Trial Update: The Efficacy and Safety of PEG-rhG-CSF in Neutropenia After Chemotherapy [Phase 4]
Phase 4 clinical trial update evaluating the efficacy and safety of PEG-rhG-CSF for neutropenia after chemotherapy in patients with breast c…
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CLINICAL_TRIALS trial_result · 2016-08-11Clinical Trial Update: Preliminary Study of Microwave Tumoral Ablation Performances for the Treatment of Pulmonary, Renal and Bone Neoplasia. [Phase 1, Phase 2]
Completed Phase 1/2 study evaluating microwave tumor ablation for lung, kidney, and bone cancers, reporting on ablation performance in these…
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CLINICAL_TRIALS research · 2016-07-01Clinical Trial Update: Cyberknife Radiosurgery and Quality of Life
The clinical trial evaluating Cyberknife radiosurgery for bone cancer and central nervous system cancer was terminated; the update notes the…