Biliary Tract Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-11-27Clinical Trial Update: Phase Ⅱ Clinical Study of Surufatinib Combined With Gemcitabine and Cisplatin Plus Durvalumab/Pembrolizumab Regimen in the Treatment of Advanced Biliary Tract Cancer [Phase 2]
Phase II trial evaluates a combination of surufatinib with gemcitabine, cisplatin, and durvalumab or pembrolizumab for advanced biliary trac…
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CLINICAL_TRIALS research · 2024-11-21Clinical Trial Update: Irinotecan Liposomes +5-FU/LV Versus Capecitabine in Patients of Recurrence After Resection of Resectable BTC [Phase 2]
Phase 2 trial comparing liposomal irinotecan plus 5-FU/leucovorin versus capecitabine in biliary tract cancer patients with recurrence after…
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CLINICAL_TRIALS trial_result · 2024-11-19Clinical Trial Update: Trial Investigating an Immunostimulatory Oncolytic Adenovirus for Cancer [Phase 1, Phase 2]
A Phase 1/2 trial of an immunostimulatory oncolytic adenovirus has completed with posted results across pancreatic adenocarcinoma, ovarian c…
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CLINICAL_TRIALS trial_result · 2024-11-13Clinical Trial Update: Basket Study of Tucatinib and Trastuzumab in Solid Tumors With HER2 Alterations [Phase 2]
Phase 2 basket trial evaluating tucatinib in combination with trastuzumab across HER2-altered solid tumors, with results posted for several …
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CLINICAL_TRIALS trial_result · 2024-11-12Clinical Trial Update: Neoadjuvant Chemotherapy With Gemcitabine Plus Cisplatin Followed by Radical Liver Resection Versus Immediate Radical Liver Resection Alone With or Without Adjuvant Chemotherapy in Incidentally Detected Gallbladder Carcinoma After Simple Cholecystectomy or in Front of Radical Resection of BTC [Phase 3]
Phase 3 trial comparing neoadjuvant gemcitabine plus cisplatin followed by liver resection versus immediate liver resection (with or without…
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CLINICAL_TRIALS withdrawal · 2024-11-12Clinical Trial Update: Neoadjuvant Tremelimumab and Durvalumab With Gem/Cis in Intrahepatic Cholangiocarcinoma [Phase 2]
Phase 2 neoadjuvant trial of tremelimumab and durvalumab with gemcitabine/cisplatin for intrahepatic cholangiocarcinoma has been withdrawn.
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CLINICAL_TRIALS trial_result · 2024-10-29Clinical Trial Update: Anlotinib Plus Nab-Paclitaxels and S-1 for Patients with Advanced Biliary Tract Cancer As Second-Line Treatment [Phase 2, Phase 3]
This document describes a Phase 2/Phase 3 clinical trial evaluating a combination of anlotinib with nab-paclitaxel and S-1 for second-line t…
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CLINICAL_TRIALS research · 2024-10-26Clinical Trial Update: A Study of Tumor-Treating Fields in Combination With Durvalumab and Gemcitabine/Cisplatin in Biliary Tract Cancers [NA]
This update reports an ongoing clinical trial evaluating tumor-treating fields in combination with durvalumab and gemcitabine/cisplatin for …
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CLINICAL_TRIALS research · 2024-10-24Clinical Trial Update: Endoscopic Retrograde Cholangiopancreatography With Radiofrequency Ablation (ERCP-RFA) Combined With Envafolimab and Surufatinib Sequential Therapy for Unresectable Biliary Tract Carcinoma [Phase 2]
Phase 2 clinical trial evaluating ERCP-RFA followed by sequential therapy with envafolimab and surufatinib for unresectable biliary tract ca…
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CLINICAL_TRIALS research · 2024-10-17Clinical Trial Update: Determination of Copper and Other Trace Elements in Serum Samples From Patients With Biliary Tract Cancers [NA]
A clinical study evaluating copper and other trace elements in serum from patients with biliary tract cancers is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-10-08Clinical Trial Update: A Study to Evaluate Abemaciclib in Advanced Biliary Tract Carcinoma [Phase 2]
The Phase 2 trial evaluating abemaciclib in advanced biliary tract cancer was terminated, and results have been posted.
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CLINICAL_TRIALS trial_result · 2024-10-02Clinical Trial Update: Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy Trial of BNT141 in Patients With Unresectable or Metastatic CLDN18.2-positive Gastric, Pancreatic, Ovarian and Biliary Tract Tumors [Phase 1, Phase 2]
Phase 1/2 trial of BNT141 in CLDN18.2-positive gastric, pancreatic, ovarian, and biliary tract cancers. The study was terminated and results…
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CLINICAL_TRIALS trial_result · 2024-09-26Clinical Trial Update: Quality of Life of Patients Over 75 Yars Undergoing Palliative Chemotherapy
The update notes a terminated clinical trial evaluating quality of life in patients over 75 undergoing palliative chemotherapy for several g…
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CLINICAL_TRIALS research · 2024-09-25Clinical Trial Update: AB122 Platform Study [Phase 1]
Phase 1 AB122 platform study is currently recruiting for advanced or metastatic solid tumors, including pancreatic ductal adenocarcinoma and…
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CLINICAL_TRIALS trial_result · 2024-08-21Clinical Trial Update: A Study of ZW25 (Zanidatamab) in Subjects With Advanced or Metastatic HER2-Amplified Biliary Tract Cancers [Phase 2]
Phase 2 study of Zanidatamab (ZW25) in advanced or metastatic HER2-amplified biliary tract cancers completed with results posted.
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CLINICAL_TRIALS trial_result · 2024-08-21Clinical Trial Update: Rucaparib in Combination With Nivolumab in Patients With Advanced or Metastatic Biliary Tract Cancer Following Platinum Therapy [Phase 2]
Phase 2 trial evaluating the combination of rucaparib and nivolumab in patients with advanced or metastatic biliary tract cancer who have pr…
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CLINICAL_TRIALS trial_result · 2024-08-20Clinical Trial Update: Effects of Red Ginseng on Gastrointestinal Symptoms and Microbiota After Surgery for Gastrointestinal Cancer [NA]
A completed clinical trial evaluating the effects of red ginseng on postoperative gastrointestinal symptoms and gut microbiota in cancer pat…
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CLINICAL_TRIALS trial_result · 2024-08-14Clinical Trial Update: Pharmacogenomics Testing in the Optimal Use of Supportive Care Medications in Stage III-IV Cancer [EARLY_Phase 1]
Early-phase trial evaluating pharmacogenomics-guided use of supportive care medications in patients with advanced cancers; the study has com…
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: A Study of Ramucirumab Plus Pembrolizumab in Participants With Gastric or GEJ Adenocarcinoma, NSCLC, Transitional Cell Carcinoma of the Urothelium, or Biliary Tract Cancer [Phase 1]
Phase 1 trial evaluating the combination of ramucirumab and pembrolizumab in gastric/GEJ adenocarcinoma, non-small cell lung cancer, urothel…
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: Pemigatinib Combined With Durvalumab for Previously Treated Biliary Tract Carcinoma [Phase 2]
Phase 2 clinical trial update evaluating pemigatinib with durvalumab for previously treated biliary tract carcinoma is not yet recruiting.
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CLINICAL_TRIALS research · 2024-07-31Clinical Trial Update: Surufatinib Combined With Serplulimab and Standard Chemotherapy as First-line Treatment in Advanced Solid Tumors With Neuroendocrine Differentiation [Phase 2]
Phase 2 study evaluating first-line surufatinib plus serplulimab with standard chemotherapy for advanced solid tumors with neuroendocrine di…
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CLINICAL_TRIALS trial_result · 2024-07-23Clinical Trial Update: My Pathway: A Study Evaluating Herceptin/Perjeta, Tarceva, Zelboraf/Cotellic, Erivedge, Alecensa, and Tecentriq Treatment Targeted Against Certain Molecular Alterations in Participants With Advanced Solid Tumors [Phase 2]
Phase 2 trial update from Genentech evaluating combinations of Herceptin, Perjeta, Tarceva, Zelboraf, Cotellic, Erivedge, Alecensa, and Tece…
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CLINICAL_TRIALS research · 2024-07-17Clinical Trial Update: Consolidative Radiotherapy (CSRT) in Patients With Oligometastatic/Locally Advanced Unresectable Bilary Tract Cancer (BTC) [Phase 2]
This clinical trial update describes a Phase 2 study evaluating consolidative radiotherapy (CSRT) in patients with oligometastatic or locall…
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CLINICAL_TRIALS trial_result · 2024-07-11Clinical Trial Update: Study of Irinotecan Liposome Injection in Patients With Advanced Biliary Tract Cancer [Phase 2]
A Phase 2 study of irinotecan liposome injection in patients with advanced biliary tract cancer has been terminated.
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CLINICAL_TRIALS research · 2024-07-08Clinical Trial Update: Durvalumab Combined With S-1 as Adjuvant Therapy of Resectable BTC [Phase 2]
Updates on a Phase 2 trial testing durvalumab plus S-1 as adjuvant therapy for resectable biliary tract cancer.