Biliary Tract Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-07-14Clinical Trial Update: A Trial of Recaticimab and Adebrelimab in Combination With Chemotherapy in Patients With Unresectable BTC [Phase 2]
This clinical trial update describes a Phase 2 study evaluating Recaticimab and Adebrelimab in combination with chemotherapy for unresectabl…
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CLINICAL_TRIALS research · 2025-07-14Clinical Trial Update: Trastuzumab Plus Chemotherapy vs Chemotherapy Alone in First-line HER2 Positive Advanced Biliary Tract Cancer Patients [Phase 3]
A Phase 3 clinical trial is investigating trastuzumab added to first-line chemotherapy versus chemotherapy alone for HER2-positive advanced …
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CLINICAL_TRIALS research · 2025-07-10Clinical Trial Update: QL1706 Combined With Lenvatinib and GEMOX as First - Line Treatment for Unresectable Biliary Tract Tumors [Phase 2]
Phase 2 trial evaluating QL1706 in combination with lenvatinib and GEMOX as first-line therapy for unresectable biliary tract tumors.
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CLINICAL_TRIALS other · 2025-07-10Clinical Trial Update: Adoptive Transfer of Tumor Infiltrating Lymphocytes for Biliary Tract Cancers [Phase 2]
This ClinicalTrials.gov entry describes a Phase 2 trial evaluating adoptive transfer of tumor infiltrating lymphocytes (TIL) for biliary tra…
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CLINICAL_TRIALS trial_result · 2025-07-10Clinical Trial Update: Feasibility Study of Multi-Platform Profiling of Resected Biliary Tract Cancer
This clinical trial update reports the termination of a feasibility study evaluating multi-platform profiling of resected biliary tract canc…
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CLINICAL_TRIALS research · 2025-07-02Clinical Trial Update: A Study of BL-B01D1+PD-1/PD-L1 Monoclonal Antibody in Patients With Advanced Biliary Tract Cancer [Phase 2]
A Phase 2 clinical trial evaluating BL-B01D1 in combination with a PD-1/PD-L1 monoclonal antibody for advanced biliary tract cancer is curre…
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: A Study to See the Effects That a New Combination of the Three Drugs, Nab-paclitaxel, Gemcitabine, and Cisplatin Has on Biliary Tract Cancer [Phase 2]
Phase 2 study evaluating nab-paclitaxel, gemcitabine, and cisplatin in unresectable biliary tract cancer; the trial is active but not recrui…
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: Durvalumab and Tremelimumab in Combination With Propranolol and Chemotherapy for Treatment of Advanced Hepatopancreabiliary Tumors (BLOCKED) [Phase 2]
Phase 2 clinical trial update evaluating durvalumab and tremelimumab in combination with propranolol and chemotherapy for advanced hepatopan…
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CLINICAL_TRIALS research · 2025-06-22Clinical Trial Update: Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors [Phase 1, Phase 2]
This trial update describes a dose-escalation and dose-expansion study of MDX2001 in patients with advanced solid tumors, currently recruiti…
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CLINICAL_TRIALS research · 2025-06-17Clinical Trial Update: Sequential Anti-Angiogenic Therapy After Immunotherapy in Advanced Biliary Tract Cancer [Phase 2]
A Phase 2 clinical trial is investigating sequential anti-angiogenic therapy after immunotherapy in advanced biliary tract cancers, includin…
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CLINICAL_TRIALS trial_result · 2025-06-04Clinical Trial Update: Envafolimab With Chemotherapy and Simvastatin in Advanced Biliary Tract Cancer [Phase 2]
A Phase 2 clinical trial update reports Envafolimab combined with chemotherapy and simvastatin for advanced biliary tract cancer, with the s…
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CLINICAL_TRIALS research · 2025-05-31Clinical Trial Update: Impact of Comprehensive Geriatric Management on Morbidity and Quality of Life in Elderly Patients Undergoing Major Hepatectomy and Pancreaticoduodenectomy for Cancer [Phase 2, Phase 3]
Phase 2/3 trial update assessing comprehensive geriatric management to reduce morbidity and improve quality of life in elderly patients unde…
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CLINICAL_TRIALS research · 2025-05-29Clinical Trial Update: GemCis Plus PD-1/PD-L1 Inhibitor in Advanced Biliary Tract Cancer: Efficacy and Immune Microenvironment （BTC-IM-1）
A clinical trial (BTC-IM-1) is evaluating the combination of GemCis (gemcitabine + cisplatin) with a PD-1/PD-L1 inhibitor in advanced biliar…
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CLINICAL_TRIALS trial_result · 2025-05-29Clinical Trial Update: Programmed Death Ligand (PD-L1) Combined With Chemotherapy for Patients With BTC [Phase 3]
A Phase 3 trial evaluating Envafolimab, a PD-L1 inhibitor, in combination with chemotherapy for biliary tract cancer, is currently active bu…
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CLINICAL_TRIALS research · 2025-05-28Clinical Trial Update: Ivonescimab in Combination With Liposomal Irinotecan and 5-FU/LV in Potentially Resectable Biliary Tract Malignancies [Phase 2]
Phase 2 clinical trial of Ivonescimab in combination with liposomal irinotecan and 5-FU/leucovorin for potentially resectable biliary tract …
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CLINICAL_TRIALS research · 2025-05-25Clinical Trial Update: An Expanded Access Treatment Protocol of Zanidatamab (ZW25) in Patients With HER2-Positive Advanced Biliary Tract Cancer
This update notes that the expanded access treatment protocol for Zanidatamab (ZW25) in patients with HER2-positive advanced biliary tract c…
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CLINICAL_TRIALS trial_result · 2025-05-23Clinical Trial Update: Testing A New Combination of Anti-cancer Immune Therapies, Atezolizumab and CDX-1127 (Varlilumab) With or Without the Addition of a Third Anti-cancer Drug, Cobimetinib, for Advanced-Stage Biliary Tract Cancer [Phase 2]
Phase 2 trial evaluating atezolizumab plus varlilumab with or without cobimetinib in advanced biliary tract cancers, with results posted in …
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CLINICAL_TRIALS trial_result · 2025-05-18Clinical Trial Update: A Phase 1 Dose-escalation Study of FF-10832 for Treatment of Solid Tumors Including Biliary Tract Cancer [Phase 1]
This is a Phase 1 dose-escalation trial update for FF-10832 in advanced solid tumors, including biliary tract cancer, currently active but n…
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CLINICAL_TRIALS trial_result · 2025-05-16Clinical Trial Update: Adjuvant Chemotherapy Regimens in Resected Biliary Tract Cancers (TOG/GI-SAFRADJU-2501)
ClinicalTrials.gov entry for an active-not-recruiting trial evaluating adjuvant chemotherapy regimens in patients with resected biliary trac…
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CLINICAL_TRIALS trial_result · 2025-05-07Clinical Trial Update: Comparison Between Winged Versus Traditional Plastic Stents for Biliary Drainage [NA]
A completed clinical trial comparing winged versus traditional plastic stents for biliary drainage. The study addressed biliary obstruction,…
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CLINICAL_TRIALS research · 2025-04-30Clinical Trial Update: Study of Combination Therapy of D07001-Softgel Capsules and Xeloda/TS-1 in Subjects With Advanced Biliary Tract Cancer [Phase 2, Phase 3]
A Phase 2/3 clinical trial update announcing recruitment for a combination of D07001-Softgel Capsules with Xeloda (capecitabine) or TS-1 in …
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CLINICAL_TRIALS research · 2025-04-22Clinical Trial Update: CDH17 CAR-T Therapy in Advanced Malignant Solid Tumors [EARLY_Phase 1]
An early-phase trial evaluating CDH17-targeted CAR-T cell therapy for advanced malignant solid tumors, including biliary tract cancer, color…
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CLINICAL_TRIALS trial_result · 2025-04-22Clinical Trial Update: A Phase 3b, Open-label, Multi-center Study on Durvalumab in Combination With Gemcitabine-based Chemotherapy as 1L Treatment for the Chinese Patients With Unresectable Biliary Tract Cancers (BTC) [Phase 3]
A Phase 3b, open-label study evaluating durvalumab plus gemcitabine-based chemotherapy as first-line treatment for unresectable biliary trac…
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CLINICAL_TRIALS research · 2025-04-20Clinical Trial Update: A Study of CTX-009 in Combination With Paclitaxel in Adult Patients With Unresectable Advanced, Metastatic or Recurrent Biliary Tract Cancers (COMPANION-002) [Phase 2, Phase 3]
Clinical trial update for COMPANION-002 evaluating CTX-009 in combination with Paclitaxel in adults with unresectable or metastatic biliary …
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CLINICAL_TRIALS research · 2025-04-09Clinical Trial Update: Oncolytic Virus H101 Combined With Lenvatinib Plus Toripalimab Compared With FOLFOX in Patients With Advanced Biliary Tract Cancer (OPTIONS-06) [Phase 2]
Phase 2 clinical trial evaluating the combination of H101 oncolytic virus with lenvatinib and toripalimab versus FOLFOX in patients with adv…