Biliary Tract Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-12-31Clinical Trial Update: Gemcitabine and Cisplatin With or Without CPI-613 as First Line Therapy for Patients With Advanced Unresectable Biliary Tract Cancer (BilT-04) [Phase 1, Phase 2]
Phase 1/2 BilT-04 trial evaluating gemcitabine and cisplatin with or without CPI-613 (devimistat) for advanced unresectable biliary tract ca…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Palliadelic Treatment to Reduce Psychological Distress in Persons With Advanced Gastrointestinal Cancers [Phase 1]
Phase 1 clinical trial evaluating Palliadelic treatment to reduce psychological distress in people with advanced pancreatic and biliary trac…
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: A Phase 1 Study of LNCB74 in Advanced Solid Tumors [Phase 1]
Status update for a Phase 1 study of the investigational agent LNCB74 in patients with various advanced solid tumors, including ovarian, bre…
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CLINICAL_TRIALS trial_result · 2025-12-16Clinical Trial Update: GEN-001 Plus Pembrolizumab for Patients With Advanced Refractory Biliary Tract Cancer [Phase 2]
Phase 2 trial evaluating GEN-001 in combination with pembrolizumab for advanced biliary tract cancer has been terminated.
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: An Exploratory Study on the Use of Ivosidenib for the Precise Treatment of Advanced Biliary Tract Malignancies With IDH1 Mutations in the Later Line of Therapy. [Phase 2]
An exploratory Phase 2 study assessing the use of ivosidenib for IDH1-mutant biliary tract cancers in later lines of therapy.
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CLINICAL_TRIALS research · 2025-12-12Clinical Trial Update: The Study of Association of Helicobacter Infections in Biliary Tract Cancers
A clinical trial update from Institute of Liver and Biliary Sciences, India, studying the association of Helicobacter infections in biliary …
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: A Study of MT-4561 in Patients With Various Advanced Solid Tumors [Phase 1, Phase 2]
This trial update reports that MT-4561 is being studied in multiple advanced solid tumors across Phase 1/Phase 2 and is currently recruiting…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: Chemoimmunotherapy Combined With Hyperthermia and Spatially-Fractionated Radiotherapy in Advanced Biliary Tract Cancer [Phase 1]
A Phase 1 clinical trial evaluating chemoimmunotherapy combined with hyperthermia and spatially-fractionated radiotherapy in advanced biliar…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Pembrolizumab With or Without Lenvatinib or Chemotherapy in First-Line Treatment of Advanced Biliary Tract Cancer [Phase 2]
A Phase 2 trial is examining pembrolizumab alone or with lenvatinib or chemotherapy as first-line treatment for advanced biliary tract cance…
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CLINICAL_TRIALS trial_result · 2025-12-08Clinical Trial Update: A Phase IIb Randomized Clinical Trial of Immune Checkpoint Inhibitor-based Maintenance Therapy in Patients With Advanced Biliary Tract Cancer [Phase 1, Phase 2]
Phase IIb randomized trial of immune checkpoint inhibitor-based maintenance therapy for advanced biliary tract cancer; the study is currentl…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Tuvonralimab and Iparomlimab Based Regimens for the Neoadjuvant Treatment of Biliary Tract Cancer [Phase 2]
Phase 2 clinical trial update evaluating regimens based on Tuvonralimab and Iparomlimab for the neoadjuvant treatment of biliary tract cance…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Targeting Driver Oncogenes With a Peptide Vaccine Plus Durvalumab and Tremelimumab for Patients With Biliary Tract Cancers (BTC) [Phase 1]
A Phase 1 clinical trial is evaluating a peptide vaccine targeting driver oncogenes in combination with durvalumab and tremelimumab for bili…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Iparomlimab and Tuvonralimab Injection Combined With GemOX and Lenvatinib as Conversion Therapy for Initially Potentially Resectable Intrahepatic Cholangiocarcinoma and Gallbladder Cancer [Phase 2]
Phase 2 clinical trial evaluating the combination of iparomlimab and tuvonralimab with GemOX chemotherapy and lenvatinib as conversion thera…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Perioperative Gemcitabine, Cisplatin, and Pembrolizumab in Potentially Resectable Biliary Tract Cancers [Phase 2]
Phase 2 perioperative regimen of gemcitabine, cisplatin, and pembrolizumab for potentially resectable biliary tract cancers; sponsored by Jo…
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CLINICAL_TRIALS trial_result · 2025-12-01Clinical Trial Update: Basket Trial Exploring the Efficacy and Safety of the Combination of Niraparib and Dostarlimab [Phase 2]
A Phase 2 basket trial evaluating the combination of niraparib and dostarlimab across multiple cancers has been terminated.
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CLINICAL_TRIALS trial_result · 2025-11-26Clinical Trial Update: Portal Vein Stenting for Malignant Obstruction: Feasibility, Safety, and Clinical Outcomes
This completed clinical trial evaluates portal vein stenting for malignant obstruction, reporting on feasibility and safety and detailing ob…
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CLINICAL_TRIALS trial_result · 2025-11-17Clinical Trial Update: Efficacy and Safety of Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) in Previously Treated Participants With Select Solid Tumors (MK-7902-005/E7080-G000-224/LEAP-005) [Phase 2]
Phase 2 trial evaluating pembrolizumab plus lenvatinib in previously treated patients with select solid tumors; results on efficacy and safe…
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CLINICAL_TRIALS trial_result · 2025-11-17Clinical Trial Update: Open Label, Multicenter, Real World Practice of Durvalumab (Imfinzi PMS)
An open-label, multicenter real-world study of durvalumab (Imfinzi) is completed, assessing its use in patients with lung cancer and biliary…
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CLINICAL_TRIALS trial_result · 2025-11-17Clinical Trial Update: Testing Ivonescimab Versus FOLFOX in Advanced Biliary Tract Cancer Patients [Phase 2]
A Phase 2 clinical trial comparing Ivonescimab to FOLFOX for advanced biliary tract cancer is currently recruiting.
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CLINICAL_TRIALS research · 2025-11-04Clinical Trial Update: Spevatamig (PT886) as Monotherapy or in Combination With Chemo and/or ICI, for the Treatment of Patients With Advanced Gastric, Gastroesophageal Junction, Pancreatic Ductal or Biliary Tract Carcinomas (the TWINPEAK Study) [Phase 1, Phase 2]
Spevatamig (PT886) is being studied as a monotherapy or in combination with chemotherapy and/or immune checkpoint inhibitors in Phase 1/2 tr…
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CLINICAL_TRIALS research · 2025-10-03Clinical Trial Update: In-Depth Characterisation of Biliary Strictures and Hepato-Pancreato-Biliary Focal Lesions for Development of New Technologies to Tackle Hepato-Pancreato-Biliary Cancers
This clinical trial protocol from the University of Nottingham aims to characterize biliary strictures and hepatobiliary–pancreatic focal le…
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CLINICAL_TRIALS trial_result · 2025-10-01Clinical Trial Update: Nal-IRI With 5-fluorouracil (5-FU) and Leucovorin or Gemcitabine Plus Cisplatin in Advanced Biliary-tract Cancer [Phase 2]
This clinical trial update notes the completion of a phase 2 study evaluating nanoliposomal irinotecan (nal-IRI) with either 5-fluorouracil/…
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CLINICAL_TRIALS research · 2025-10-01Clinical Trial Update: Tissue Procurement for Gastric Cancer, Gastrointestinal Stromal Tumors (GIST), Esophageal Cancer, Pancreas Cancer, Hepatocellular Cancer, Biliary Cancer, Neuroendocrine, Peritoneal Mesothelioma, Anal Cancer and Colorectal Cancer in Patients Undergoing Surgery or Biopsy
University of Chicago is recruiting for a tissue procurement study across multiple cancers in patients undergoing surgery or biopsy to colle…
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CLINICAL_TRIALS trial_result · 2025-09-29Clinical Trial Update: Phase Ib/II Single-arm Study of mFOLFOX6, Bevacizumab and Atezolizumab in Advanced Biliary Tract Cancer [Phase 1, Phase 2]
Phase Ib/II single-arm study evaluating mFOLFOX6 with Bevacizumab and Atezolizumab in advanced biliary tract cancer has completed.
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CLINICAL_TRIALS research · 2025-09-25Clinical Trial Update: Study of LY3537982 in Cancer Patients With a Specific Genetic Mutation (KRAS G12C) [Phase 1, Phase 2]
This clinical trial update reports Eli Lilly's KRAS G12C inhibitor LY3537982 is being studied in Phase 1/2 trials across multiple KRAS G12C-…