Biliary Tract Cancer
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CLINICAL_TRIALS trial_result · 2019-02-21Clinical Trial Update: A Phase II Trial of Preoperative Chemotherapy for Biliary Tract Cancer (BTC) With Node Metastasis [Phase 2]
This document provides an update on a Phase II preoperative chemotherapy trial for biliary tract cancer with node metastasis.
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CLINICAL_TRIALS research · 2019-02-12Clinical Trial Update: Whole-Exome Sequencing (WES) of Intraductal Neoplasms of the Bile Duct (IPNB)
Clinical trial update describing the use of whole-exome sequencing to study intraductal neoplasms of the bile duct, including biliary tract …
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CLINICAL_TRIALS trial_result · 2019-01-30Clinical Trial Update: A Phase 2 Trial of Regorafenib as A Single Agent in Advanced and Metastatic Biliary Tract Carcinoma/Cholangiocarcinoma Patients Who Have Failed First-line Chemotherapy [Phase 2]
This update reports results from a Phase 2 single-agent trial of regorafenib in patients with advanced or metastatic biliary tract carcinoma…
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CLINICAL_TRIALS trial_result · 2019-01-22Clinical Trial Update: BIBW 2992 as add-on to Gem/Cis in Advanced Biliary Tract Cancer [Phase 1]
Phase 1 trial update evaluating BIBW 2992 (afatinib) as add-on to gemcitabine/cisplatin in advanced biliary tract cancer; study terminated w…
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CLINICAL_TRIALS trial_result · 2018-09-10Clinical Trial Update: Study of TH-302 Monotherapy as Second-line Treatment in Advanced Biliary Tract Cancer [Phase 2]
Phase 2 trial update of TH-302 monotherapy as second-line treatment in advanced biliary tract cancer has completed.
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CLINICAL_TRIALS trial_result · 2018-06-28Clinical Trial Update: A Study of Varlitinib in Japanese Subjects With Advanced or Metastatic Solid Tumours [Phase 1]
Phase 1 study of varlitinib in Japanese patients with advanced or metastatic solid tumors, including biliary tract cancer, has completed.
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CLINICAL_TRIALS trial_result · 2018-06-11Clinical Trial Update: Preoperative Nutritional Support in Malnutritional Cancer Patients [NA]
A completed clinical trial evaluated preoperative nutritional support in malnourished cancer patients, focusing on pancreatic and biliary ca…
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CLINICAL_TRIALS withdrawal · 2018-05-23Clinical Trial Update: Study of Varlitinib Plus Capecitabine in Patients With Advanced or Metastatic Biliary Tract Cancer [Phase 2]
Phase 2 study of Varlitinib plus Capecitabine for advanced or metastatic biliary tract cancer has been withdrawn.
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CLINICAL_TRIALS trial_result · 2018-05-16Clinical Trial Update: Phase II Study of Gemcitabine Versus S-1 Adjuvant Therapy After Hemihepatectomy for Biliary Tract Cancer [Phase 2]
Phase II randomized trial comparing gemcitabine to S-1 as adjuvant therapy after hemihepatectomy for biliary tract cancer; the study has com…
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CLINICAL_TRIALS trial_result · 2018-04-25Clinical Trial Update: Capecitabine, Oxaliplatin, Bevacizumab and Radiation Therapy in Patients With Biliary Tract and Gallbladder Cancer [Phase 2]
This clinical trial update reports the results of a Phase 2 study evaluating capecitabine, oxaliplatin, and bevacizumab with radiation thera…
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CLINICAL_TRIALS trial_result · 2018-03-15Clinical Trial Update: Development and Clinical Validation of Ketogen-based Therapeutic Diet for Pancreaticobiliary Cancer Patients [NA]
The clinical trial evaluating a Ketogen-based Therapeutic Diet for pancreaticobiliary cancer has completed, with Yonsei University as sponso…
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CLINICAL_TRIALS trial_result · 2018-02-13Clinical Trial Update: Second-line Irinotecan and Capecitabine Versus Irinotecan for Gemcitabine and Cisplatin Refractory Biliary Tract Cancer [Phase 2]
Phase 2 clinical trial comparing second-line irinotecan and capecitabine versus irinotecan for biliary tract cancer after gemcitabine and ci…
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CLINICAL_TRIALS trial_result · 2017-11-17Clinical Trial Update: A Phase I Study of Adjuvant Chemotherapy With GC in Biliary Tract Cancer Undergoing Resection Without Major Hepatectomy [Phase 1]
Completed Phase I study evaluating adjuvant chemotherapy with gemcitabine and cisplatin (GC) in biliary tract cancer patients undergoing sur…
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CLINICAL_TRIALS research · 2017-10-17Clinical Trial Update: Study of PD-1 Inhibitor in Combination With Gemcitabine/Cisplatin for Advancer BTCs [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating a PD-1 inhibitor in combination with gemcitabine and cisplatin for advanced biliary tract cancer; t…
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CLINICAL_TRIALS trial_result · 2017-10-09Clinical Trial Update: A Phase I Study of Adjuvant Chemotherapy With GS in Biliary Tract Cancer Undergoing Resection Without Major Hepatectomy [Phase 1]
This document reports the completion of a Phase I trial evaluating adjuvant chemotherapy with GS (gemcitabine and S-1) in biliary tract canc…
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CLINICAL_TRIALS trial_result · 2017-08-23Clinical Trial Update: Study of Oxaliplatin, Irinotecan, and S-1 in Biliary Tract Cancer [Phase 2]
Phase 2 study evaluating a combination of oxaliplatin, irinotecan, and S-1 in biliary tract cancer.
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FDA approval · 2017-08-03FDA Approved: GEMCITABINE — Original Application (Accord Healthcare Inc.)
FDA approved Accord Healthcare's gemcitabine injectable drug as an original application, providing a generic version of the anticancer agent…
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CLINICAL_TRIALS trial_result · 2017-05-09Clinical Trial Update: Apatinib as Second Line Therapy in Patients With Advanced Refractory Biliary Tract Cancers [Phase 2]
This document provides a Phase 2 trial update on apatinib as second-line therapy for advanced refractory biliary tract cancers.
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CLINICAL_TRIALS trial_result · 2017-04-26Clinical Trial Update: Phase II Study of Refametinib, a MEK Inhibitor, as Second-line Treatment in Advanced Biliary Tract Adenocarcinoma [Phase 2]
This document reports the completion of a Phase II trial of Refametinib, a MEK inhibitor, as second-line treatment for advanced biliary trac…
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CLINICAL_TRIALS trial_result · 2017-04-24Clinical Trial Update: Endoscopic Therapy of Malignant Bile Duct Strictures [NA]
The trial examining endoscopic therapy for malignant bile duct strictures was terminated, with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-02-07Clinical Trial Update: Gemcitabine, Oxaliplatin in Combination With Bevacizumab in Biliary Tract and Gallbladder Cancer [Phase 2]
A Phase 2 trial evaluating the combination of gemcitabine, oxaliplatin, and bevacizumab in biliary tract cancers (including gallbladder aden…
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CLINICAL_TRIALS research · 2017-01-26Clinical Trial Update: Duct-to-mucosa Versus Invagination for Pancreaticojejunostomy [NA]
This entry notes a clinical trial comparing duct-to-mucosa versus invagination techniques for pancreaticojejunostomy, involving pancreatic c…
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CLINICAL_TRIALS trial_result · 2017-01-04Clinical Trial Update: Study of Hepatic Arterial Infusion to Treat Biliary Tract Carcinomas [Phase 2]
Phase 2 study of hepatic arterial infusion for biliary tract cancer has completed.
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CLINICAL_TRIALS trial_result · 2016-12-09Clinical Trial Update: Early Palliative Care on Quality of Life of Advanced Cancer Patients [Phase 3]
A Phase 3 trial evaluating whether early palliative care improves quality of life in advanced cancers. The study includes non-small cell lun…
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FDA approval · 2016-11-17FDA Approved: GEMCITABINE — Supplemental Application (Hospira, Inc.)
FDA approved Hospira, Inc.'s supplemental application for gemcitabine under ANDA 079183. This represents approval of a supplemental submissi…