Biliary Tract Cancer

• CLINICAL_TRIALS trial_result · 2023-12-07
  Clinical Trial Update: A Phase 1/2 Study of INCB001158 in Combination With Chemotherapy in Subjects With Solid Tumors [Phase 1, Phase 2]

  Results from a Phase 1/2 study of INCB001158 in combination with chemotherapy for solid tumors, including biliary tract cancer and colorecta…

• CLINICAL_TRIALS trial_result · 2023-12-06
  Clinical Trial Update: Cadonilimab Plus Regorafenib and Gem-Cis Chemotherapy in Advanced Biliary Tract Cancer [Phase 2]

  Phase 2 clinical trial update evaluating cadonilimab plus regorafenib and gemcitabine-cisplatin chemotherapy in advanced biliary tract cance…

• CLINICAL_TRIALS trial_result · 2023-11-29
  Clinical Trial Update: A Study of the Efficacy and Safety of Chemotherapy Combined With Toripalimab in Advanced Biliary Tract Cancer [Phase 2]

  Phase 2 clinical trial evaluating chemotherapy plus toripalimab for advanced biliary tract cancer has completed.

• CLINICAL_TRIALS trial_result · 2023-11-24
  Clinical Trial Update: Study of D07001-Softgel Capsules in Subjects With Gastrointestinal Cancer in Dose-Escalation Phase and in Subjects With Biliary Tract Cancer in Dose-Expansion Phase [Phase 1, Phase 2]

  Phase 1 dose-escalation and Phase 2 dose-expansion study of D07001-Softgel Capsules in gastrointestinal and biliary tract cancers completed …

• CLINICAL_TRIALS trial_result · 2023-11-18
  Clinical Trial Update: Combination Therapy of HAIC, Surufatinib and Tislelizumab for Unresectable or Metastatic Biliary Tract Cancer [Phase 2]

  Phase 2 clinical trial investigating a combination of hepatic artery infusion chemotherapy (HAIC), surufatinib, and tislelizumab for unresec…

• Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
• CLINICAL_TRIALS trial_result · 2023-11-15
  Clinical Trial Update: Durvalumab and Lenvatinib With or Without Chemotherapy in First-Line Treatment of Advanced Biliary Tract Cancer [Phase 2]

  A Phase 2 trial evaluating durvalumab and lenvatinib with or without chemotherapy as first-line treatment for advanced biliary tract cancer …

• CLINICAL_TRIALS trial_result · 2023-11-03
  Clinical Trial Update: Pembrolizumab in Biliary Tract Cancer [Phase 2]

  Phase 2 trial update of pembrolizumab in biliary tract cancer has been completed.

• CLINICAL_TRIALS trial_result · 2023-10-13
  Clinical Trial Update: Olaparib in Treating Patients With Metastatic Biliary Tract Cancer With Aberrant DNA Repair Gene Mutations [Phase 2]

  Phase 2 trial investigating olaparib for metastatic biliary tract cancer with aberrant DNA repair gene mutations.

• CLINICAL_TRIALS trial_result · 2023-10-11
  Clinical Trial Update: Trastuzumab-pkrb Combined With Modified FOLFOX-6 in Biliary Tract Cancer Patients Progressed on First Line Therapy [Phase 2]

  Phase 2 trial evaluating trastuzumab-pkrb with modified FOLFOX-6 in HER2-positive biliary tract cancer progressed after first-line therapy h…

• CLINICAL_TRIALS trial_result · 2023-09-22
  Clinical Trial Update: Immune Checkpoint Inhibition in Combination With Radiation Therapy in Pancreatic Cancer or Biliary Tract Cancer Patients [Phase 2]

  Phase 2 trial investigating immune checkpoint inhibitors combined with radiation therapy in metastatic pancreatic cancer and metastatic bili…

• CLINICAL_TRIALS trial_result · 2023-09-13
  Clinical Trial Update: Anlotinib Plus TQB2450 Combined With Nab-paclitaxel and Cisplatin as First-line Treatment for Advanced Biliary Tract Cancer [Phase 2]

  Phase 2 trial update evaluating anlotinib plus TQB2450 with nab-paclitaxel and cisplatin as first-line treatment for advanced biliary tract …

• CLINICAL_TRIALS trial_result · 2023-08-15
  Clinical Trial Update: Tislelizumab（Anti PD-1), Lenvatinib and GEMOX Transformation in the Treatment of Potentially Resectable, Locally Advanced Biliary Tract Cancer [Phase 2]

  Phase 2 clinical trial update investigating tislelizumab with lenvatinib and GEMOX for potentially resectable, locally advanced biliary trac…

• CLINICAL_TRIALS trial_result · 2023-07-03
  Clinical Trial Update: A Phase 1/2 Study of CAN04 in Combination With Different Chemotherapy Regimens in Subjects With Advanced Solid Tumors [Phase 1, Phase 2]

  Phase 1/2 study of CAN04 in combination with various chemotherapy regimens for advanced solid tumors has completed.

• CLINICAL_TRIALS trial_result · 2023-06-29
  Clinical Trial Update: A Study of Atezolizumab With or Without Bevacizumab in Combination With Cisplatin Plus Gemcitabine in Patients With Untreated, Advanced Biliary Tract Cancer [Phase 2]

  A Phase 2 trial evaluated atezolizumab with or without bevacizumab in combination with cisplatin and gemcitabine for untreated, advanced bil…

• CLINICAL_TRIALS trial_result · 2023-06-27
  Clinical Trial Update: Oncolytic Virotherapy Combined With Tislelizumab Plus Lenvatinib in Patients With Advanced Biliary Tract Cancer (OPTIONS-05) [Phase 2]

  Phase 2 clinical trial exploring a combination of oncolytic virotherapy with tislelizumab and lenvatinib in advanced biliary tract cancer.

• CLINICAL_TRIALS trial_result · 2023-06-23
  Clinical Trial Update: HAIC With Oxaliplatin, 5-FU and Bevacizumab Plus Intravenous Toripalimab for Advanced BTC [Phase 2]

  A Phase 2 trial evaluating hepatic arterial infusion chemotherapy with oxaliplatin, 5-fluorouracil, and bevacizumab in combination with intr…

• CLINICAL_TRIALS trial_result · 2023-05-24
  Clinical Trial Update: Comparing NUC-1031 Plus Cisplatin to Gemcitabine Plus Cisplatin in Patients With Advanced Biliary Tract Cancer [Phase 3]

  Phase 3 trial comparing NUC-1031 plus cisplatin versus gemcitabine plus cisplatin in advanced biliary tract cancer was terminated with resul…

• CLINICAL_TRIALS trial_result · 2023-04-19
  Clinical Trial Update: A Safety and Efficacy Study of XERMELO® + First-line Chemotherapy in Patients With Advanced Biliary Tract Cancer [Phase 2]

  Phase 2 trial update for XERMELO in combination with first-line chemotherapy in advanced biliary tract cancer; the study is terminated with …

• CLINICAL_TRIALS trial_result · 2023-04-13
  Clinical Trial Update: Durvalumab or Placebo in Combination With Gemcitabine/Cisplatin in Patients With 1st Line Advanced Biliary Tract Cancer (TOPAZ-1) [Phase 3]

  Phase 3 TOPAZ-1 trial results for durvalumab in combination with gemcitabine/cisplatin in first-line biliary tract cancer have been posted.

• CLINICAL_TRIALS trial_result · 2023-04-03
  Clinical Trial Update: IBI310 in Combination With Sintilimab in Patients With Advanced Biliary Tract Cancer [Phase 1, Phase 2]

  Phase 1/2 trial evaluating IBI310 in combination with sintilimab for advanced biliary tract cancer is ongoing; current status is unknown.

• CLINICAL_TRIALS trial_result · 2023-03-29
  Clinical Trial Update: Toripalimab Plus Lenvatinib as Second-line Treatment in Advanced Biliary Tract Cancers [Phase 2]

  Phase 2 trial update evaluating toripalimab plus lenvatinib as second-line treatment for advanced biliary tract cancer.

• CLINICAL_TRIALS trial_result · 2023-03-24
  Clinical Trial Update: Cryoablation Combined With Sintilimab Plus Lenvatinib in Patients With Immune Checkpoint Inhibitor Previously Treated Advanced Biliary Tract Cancer （CASTLE-08） [Phase 2]

  Phase 2 trial evaluating cryoablation with sintilimab and lenvatinib in patients with advanced biliary tract cancer who have previously rece…

• CLINICAL_TRIALS trial_result · 2023-03-03
  Clinical Trial Update: A Phase I/II Study of Regorafenib Plus Avelumab in Solid Tumors [Phase 1, Phase 2]

  A Phase I/II study investigating regorafenib in combination with avelumab in various solid tumors, spanning Phase 1 and Phase 2 cohorts.

• CLINICAL_TRIALS trial_result · 2023-02-24
  Clinical Trial Update: A Phase Ib/II Clinical Study of Camrelizumab and Apatinib Plus GP in the Treatment of Advanced Biliary Tract Cancer [Phase 1, Phase 2]

  Phase Ib/II clinical trial evaluating camrelizumab and apatinib plus GP in locally advanced or metastatic biliary tract cancer; status is un…

• CLINICAL_TRIALS trial_result · 2023-01-26
  Clinical Trial Update: Combination of Gemcitabine, Oxaliplatin, Sintilimab and Bevacizumab in Unresectable Biliary Tract Cancer [Phase 2]

  Phase 2 trial investigating a Gemcitabine, Oxaliplatin, Sintilimab, and Bevacizumab combination in unresectable biliary tract cancer.