Biliary Tract Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-11-13Clinical Trial Update: Basket Study of Tucatinib and Trastuzumab in Solid Tumors With HER2 Alterations [Phase 2]
Phase 2 basket trial evaluating tucatinib in combination with trastuzumab across HER2-altered solid tumors, with results posted for several …
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CLINICAL_TRIALS trial_result · 2024-11-12Clinical Trial Update: Neoadjuvant Chemotherapy With Gemcitabine Plus Cisplatin Followed by Radical Liver Resection Versus Immediate Radical Liver Resection Alone With or Without Adjuvant Chemotherapy in Incidentally Detected Gallbladder Carcinoma After Simple Cholecystectomy or in Front of Radical Resection of BTC [Phase 3]
Phase 3 trial comparing neoadjuvant gemcitabine plus cisplatin followed by liver resection versus immediate liver resection (with or without…
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CLINICAL_TRIALS trial_result · 2024-10-29Clinical Trial Update: Anlotinib Plus Nab-Paclitaxels and S-1 for Patients with Advanced Biliary Tract Cancer As Second-Line Treatment [Phase 2, Phase 3]
This document describes a Phase 2/Phase 3 clinical trial evaluating a combination of anlotinib with nab-paclitaxel and S-1 for second-line t…
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CLINICAL_TRIALS trial_result · 2024-10-08Clinical Trial Update: A Study to Evaluate Abemaciclib in Advanced Biliary Tract Carcinoma [Phase 2]
The Phase 2 trial evaluating abemaciclib in advanced biliary tract cancer was terminated, and results have been posted.
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CLINICAL_TRIALS trial_result · 2024-10-02Clinical Trial Update: Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy Trial of BNT141 in Patients With Unresectable or Metastatic CLDN18.2-positive Gastric, Pancreatic, Ovarian and Biliary Tract Tumors [Phase 1, Phase 2]
Phase 1/2 trial of BNT141 in CLDN18.2-positive gastric, pancreatic, ovarian, and biliary tract cancers. The study was terminated and results…
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CLINICAL_TRIALS trial_result · 2024-09-26Clinical Trial Update: Quality of Life of Patients Over 75 Yars Undergoing Palliative Chemotherapy
The update notes a terminated clinical trial evaluating quality of life in patients over 75 undergoing palliative chemotherapy for several g…
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CLINICAL_TRIALS trial_result · 2024-08-21Clinical Trial Update: A Study of ZW25 (Zanidatamab) in Subjects With Advanced or Metastatic HER2-Amplified Biliary Tract Cancers [Phase 2]
Phase 2 study of Zanidatamab (ZW25) in advanced or metastatic HER2-amplified biliary tract cancers completed with results posted.
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CLINICAL_TRIALS trial_result · 2024-08-21Clinical Trial Update: Rucaparib in Combination With Nivolumab in Patients With Advanced or Metastatic Biliary Tract Cancer Following Platinum Therapy [Phase 2]
Phase 2 trial evaluating the combination of rucaparib and nivolumab in patients with advanced or metastatic biliary tract cancer who have pr…
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CLINICAL_TRIALS trial_result · 2024-08-20Clinical Trial Update: Effects of Red Ginseng on Gastrointestinal Symptoms and Microbiota After Surgery for Gastrointestinal Cancer [NA]
A completed clinical trial evaluating the effects of red ginseng on postoperative gastrointestinal symptoms and gut microbiota in cancer pat…
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CLINICAL_TRIALS trial_result · 2024-08-14Clinical Trial Update: Pharmacogenomics Testing in the Optimal Use of Supportive Care Medications in Stage III-IV Cancer [EARLY_Phase 1]
Early-phase trial evaluating pharmacogenomics-guided use of supportive care medications in patients with advanced cancers; the study has com…
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: A Study of Ramucirumab Plus Pembrolizumab in Participants With Gastric or GEJ Adenocarcinoma, NSCLC, Transitional Cell Carcinoma of the Urothelium, or Biliary Tract Cancer [Phase 1]
Phase 1 trial evaluating the combination of ramucirumab and pembrolizumab in gastric/GEJ adenocarcinoma, non-small cell lung cancer, urothel…
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: Pemigatinib Combined With Durvalumab for Previously Treated Biliary Tract Carcinoma [Phase 2]
Phase 2 clinical trial update evaluating pemigatinib with durvalumab for previously treated biliary tract carcinoma is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2024-07-23Clinical Trial Update: My Pathway: A Study Evaluating Herceptin/Perjeta, Tarceva, Zelboraf/Cotellic, Erivedge, Alecensa, and Tecentriq Treatment Targeted Against Certain Molecular Alterations in Participants With Advanced Solid Tumors [Phase 2]
Phase 2 trial update from Genentech evaluating combinations of Herceptin, Perjeta, Tarceva, Zelboraf, Cotellic, Erivedge, Alecensa, and Tece…
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CLINICAL_TRIALS trial_result · 2024-07-11Clinical Trial Update: Study of Irinotecan Liposome Injection in Patients With Advanced Biliary Tract Cancer [Phase 2]
A Phase 2 study of irinotecan liposome injection in patients with advanced biliary tract cancer has been terminated.
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CLINICAL_TRIALS trial_result · 2024-05-02Clinical Trial Update: Nutritional Support for Patients Operated for Malignant Tumors in HPD Zone [NA]
Completed clinical trial evaluating nutritional support for patients operated for hepatobiliary neoplasms.
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CLINICAL_TRIALS trial_result · 2024-04-29Clinical Trial Update: HAIC+Adebrelimab+Lenvatinib for Conversion Treatment of Potentially Resectable, Locally Advanced Biliary Tract Cancer [Phase 2]
Phase 2 trial evaluating HAIC plus Adebrelimab and Lenvatinib as conversion therapy for potentially resectable, locally advanced biliary tra…
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CLINICAL_TRIALS trial_result · 2024-04-19Clinical Trial Update: Phase II Study of Sitravatinib in Combination With Tislelizumab in Patients With Advanced Biliary Tract Cancer [Phase 2]
Phase II trial evaluating combination of sitravatinib and tislelizumab in patients with advanced biliary tract cancer.
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CLINICAL_TRIALS trial_result · 2024-04-19Clinical Trial Update: DDR-Umbrella Study of DDR Targeting Agents in Advanced Biliary Tract Cancer [Phase 2]
Phase 2 umbrella trial evaluating DDR-targeting agents in advanced biliary tract cancer; currently active but not recruiting.
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CLINICAL_TRIALS trial_result · 2024-04-19Clinical Trial Update: Durvalumab(MEDI4736)/Tremelimumab in Combination With Gemcitabine/Cisplatin in Chemotherapy-naïve Biliary Tract Cancer [Phase 2]
Phase 2 trial evaluating Durvalumab (MEDI4736) and Tremelimumab with gemcitabine/cisplatin in chemotherapy-naïve biliary tract cancer (activ…
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CLINICAL_TRIALS trial_result · 2024-04-10Clinical Trial Update: Study of the Combination of DKN-01 and Nivolumab in Previously Treated Patients With Advanced Biliary Tract Cancer (BTC) [Phase 2]
Phase 2 trial of DKN-01 plus nivolumab in advanced biliary tract cancer has been terminated; results were posted on 2024-04-10.
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CLINICAL_TRIALS trial_result · 2024-02-13Clinical Trial Update: Durvalumab Combined With Surufatinib as Maintenance Therapy in Patients With Advanced Biliary Tract Cancer [Phase 1, Phase 2]
Phase 1/2 trial evaluating durvalumab with surufatinib as maintenance therapy in advanced biliary tract cancer.
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CLINICAL_TRIALS trial_result · 2024-02-08Clinical Trial Update: Exploratory Study on the Therapeutic Effect Prediction Model of Advanced BTC Immunotherapy [Phase 1, Phase 2]
An exploratory Phase 1/2 trial evaluating a therapeutic effect prediction model for biliary tract cancer in the context of immunotherapy.
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CLINICAL_TRIALS trial_result · 2024-01-30Clinical Trial Update: Camrelizumab Combined With Apatinib and Capecitabine in Patients With Advanced Biliary Tract Cancer. [Phase 2]
Phase 2 trial evaluating camrelizumab with apatinib and capecitabine in advanced biliary tract cancer has completed.
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CLINICAL_TRIALS trial_result · 2023-12-22Clinical Trial Update: Pembrolizumab (MK-3475) Plus Gemcitabine/Cisplatin Versus Placebo Plus Gemcitabine/Cisplatin for First-Line Advanced and/or Unresectable Biliary Tract Carcinoma (BTC) (MK-3475-966/KEYNOTE-966) [Phase 3]
A Phase 3 trial (MK-3475-966/KEYNOTE-966) evaluating pembrolizumab plus gemcitabine/cisplatin versus placebo plus gemcitabine/cisplatin as f…
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CLINICAL_TRIALS trial_result · 2023-12-20Clinical Trial Update: A Study of RC48-ADC in Subjects With HER2 Overexpressed Metastatic Biliary Tract Cancer [Phase 2]
Phase 2 clinical trial update for RC48-ADC in HER2-overexpressed metastatic biliary tract cancer.