Biliary Tract Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-11-17Clinical Trial Update: Open Label, Multicenter, Real World Practice of Durvalumab (Imfinzi PMS)
An open-label, multicenter real-world study of durvalumab (Imfinzi) is completed, assessing its use in patients with lung cancer and biliary…
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CLINICAL_TRIALS trial_result · 2025-11-17Clinical Trial Update: Testing Ivonescimab Versus FOLFOX in Advanced Biliary Tract Cancer Patients [Phase 2]
A Phase 2 clinical trial comparing Ivonescimab to FOLFOX for advanced biliary tract cancer is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-10-01Clinical Trial Update: Nal-IRI With 5-fluorouracil (5-FU) and Leucovorin or Gemcitabine Plus Cisplatin in Advanced Biliary-tract Cancer [Phase 2]
This clinical trial update notes the completion of a phase 2 study evaluating nanoliposomal irinotecan (nal-IRI) with either 5-fluorouracil/…
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CLINICAL_TRIALS trial_result · 2025-09-29Clinical Trial Update: Phase Ib/II Single-arm Study of mFOLFOX6, Bevacizumab and Atezolizumab in Advanced Biliary Tract Cancer [Phase 1, Phase 2]
Phase Ib/II single-arm study evaluating mFOLFOX6 with Bevacizumab and Atezolizumab in advanced biliary tract cancer has completed.
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CLINICAL_TRIALS trial_result · 2025-09-12Clinical Trial Update: A Safety and Efficacy Study of ZW25 (Zanidatamab) Plus Combination Chemotherapy in HER2-expressing Gastrointestinal Cancers, Including Gastroesophageal Adenocarcinoma, Biliary Tract Cancer, and Colorectal Cancer [Phase 2]
Phase 2 study evaluating ZW25 (zanidatamab) in combination chemotherapy for HER2-expressing gastrointestinal cancers, including gastroesopha…
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CLINICAL_TRIALS trial_result · 2025-09-03Clinical Trial Update: Combination of QLS31905 and Chemotherapy ± QL2107 in Patients With CLDN18.2-positive Advanced Biliary Tract Cancer [Phase 2]
A Phase 2 clinical trial is studying QLS31905 in combination with chemotherapy, with or without QL2107, for CLDN18.2-positive advanced bilia…
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CLINICAL_TRIALS trial_result · 2025-08-27Clinical Trial Update: Blood Flow Restriction Exercise in Patients With Pancreatic, Biliary Tract, and Liver Cancer (PREV-Ex) [NA]
ClinicalTrials.gov update reports that the PREV-Ex trial evaluating blood flow restriction exercise in patients with pancreatic cancer, bili…
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CLINICAL_TRIALS trial_result · 2025-08-26Clinical Trial Update: Biomarker Discovery in Patients With Advanced Biliary Tract Cancer
A completed clinical trial update describing biomarker discovery efforts in patients with advanced biliary tract cancer, including cholangio…
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CLINICAL_TRIALS trial_result · 2025-07-22Clinical Trial Update: NGS as the First-line Treatment in Advanced Biliary Tract Cancer [Phase 2]
A Phase 2 trial evaluating next-generation sequencing-guided first-line treatment for advanced biliary tract cancer has completed.
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CLINICAL_TRIALS trial_result · 2025-07-10Clinical Trial Update: Feasibility Study of Multi-Platform Profiling of Resected Biliary Tract Cancer
This clinical trial update reports the termination of a feasibility study evaluating multi-platform profiling of resected biliary tract canc…
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CLINICAL_TRIALS trial_result · 2025-06-04Clinical Trial Update: Envafolimab With Chemotherapy and Simvastatin in Advanced Biliary Tract Cancer [Phase 2]
A Phase 2 clinical trial update reports Envafolimab combined with chemotherapy and simvastatin for advanced biliary tract cancer, with the s…
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CLINICAL_TRIALS trial_result · 2025-05-29Clinical Trial Update: Programmed Death Ligand (PD-L1) Combined With Chemotherapy for Patients With BTC [Phase 3]
A Phase 3 trial evaluating Envafolimab, a PD-L1 inhibitor, in combination with chemotherapy for biliary tract cancer, is currently active bu…
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CLINICAL_TRIALS trial_result · 2025-05-23Clinical Trial Update: Testing A New Combination of Anti-cancer Immune Therapies, Atezolizumab and CDX-1127 (Varlilumab) With or Without the Addition of a Third Anti-cancer Drug, Cobimetinib, for Advanced-Stage Biliary Tract Cancer [Phase 2]
Phase 2 trial evaluating atezolizumab plus varlilumab with or without cobimetinib in advanced biliary tract cancers, with results posted in …
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CLINICAL_TRIALS trial_result · 2025-05-18Clinical Trial Update: A Phase 1 Dose-escalation Study of FF-10832 for Treatment of Solid Tumors Including Biliary Tract Cancer [Phase 1]
This is a Phase 1 dose-escalation trial update for FF-10832 in advanced solid tumors, including biliary tract cancer, currently active but n…
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CLINICAL_TRIALS trial_result · 2025-05-16Clinical Trial Update: Adjuvant Chemotherapy Regimens in Resected Biliary Tract Cancers (TOG/GI-SAFRADJU-2501)
ClinicalTrials.gov entry for an active-not-recruiting trial evaluating adjuvant chemotherapy regimens in patients with resected biliary trac…
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CLINICAL_TRIALS trial_result · 2025-05-07Clinical Trial Update: Comparison Between Winged Versus Traditional Plastic Stents for Biliary Drainage [NA]
A completed clinical trial comparing winged versus traditional plastic stents for biliary drainage. The study addressed biliary obstruction,…
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CLINICAL_TRIALS trial_result · 2025-04-22Clinical Trial Update: A Phase 3b, Open-label, Multi-center Study on Durvalumab in Combination With Gemcitabine-based Chemotherapy as 1L Treatment for the Chinese Patients With Unresectable Biliary Tract Cancers (BTC) [Phase 3]
A Phase 3b, open-label study evaluating durvalumab plus gemcitabine-based chemotherapy as first-line treatment for unresectable biliary trac…
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CLINICAL_TRIALS trial_result · 2025-04-06Clinical Trial Update: Preventing Viral Pandemic Associated Risk of Cancer Death Using Less Invasive Diagnostic Tests- Liquid Biopsies
Completed clinical trial update evaluating the use of liquid biopsies to reduce cancer death risk during viral pandemics. The provided snipp…
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CLINICAL_TRIALS trial_result · 2025-03-30Clinical Trial Update: Clinical Correlation Study Between Anomalous Pancreaticobiliary Ductal Junction and Malignant Tumors of the Biliary System and the Establishment of an AI-based Automated Recognition System
This completed clinical trial investigated the relationship between anomalous pancreaticobiliary ductal junction and malignant tumors of the…
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CLINICAL_TRIALS trial_result · 2025-02-10Clinical Trial Update: Inetetamab Plus Chemotherapy ± PD-1/PD-L1 in HER2+ Advanced Biliary Cancer [Phase 4]
A Phase 4 clinical trial update describes inetetamab plus chemotherapy with optional PD-1/PD-L1 inhibition for HER2-positive metastatic bili…
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CLINICAL_TRIALS trial_result · 2025-01-27Clinical Trial Update: A Study of CTX-009 (ABL001) in Combination With Irinotecan or Paclitaxel in Advanced or Metastatic Solid Tumor Patients [Phase 1, Phase 2]
A phase 1/2 study of CTX-009 (ABL001) in combination with irinotecan or paclitaxel for advanced/metastatic solid tumors, including biliary t…
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CLINICAL_TRIALS trial_result · 2025-01-27Clinical Trial Update: Adebrelimab With or Without SHR-8068 in Combination With Cisplatin Plus Gemcitabine as First-line Treatment in Patients With Advanced Biliary Tract Cancer [Phase 2]
This is an ongoing Phase 2 trial evaluating adebrelimab with or without SHR-8068 in combination with cisplatin and gemcitabine as first-line…
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CLINICAL_TRIALS trial_result · 2025-01-22Clinical Trial Update: Combination Therapy With NC-6004 and Gemcitabine in Advanced Solid Tumors or Non-Small Cell Lung, Biliary and Bladder Cancer [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating NC-6004 (a cisplatin nanoparticle formulation) in combination with gemcitabine has completed testing i…
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CLINICAL_TRIALS trial_result · 2024-12-09Clinical Trial Update: A Study Evaluating Safety, Pharmacokinetics, Pharmacodynamics, And Clinical Activity Of RO7119929 (TLR7 Agonist) In Participants With Unresectable Advanced Or Metastatic Hepatocellular Carcinoma, Biliary Tract Cancer, Or Solid Tumors With Hepatic Metastases [Phase 1]
Phase 1 study assessing safety, pharmacokinetics, pharmacodynamics, and preliminary clinical activity of RO7119929 (TLR7 agonist) in partici…
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CLINICAL_TRIALS trial_result · 2024-11-19Clinical Trial Update: Trial Investigating an Immunostimulatory Oncolytic Adenovirus for Cancer [Phase 1, Phase 2]
A Phase 1/2 trial of an immunostimulatory oncolytic adenovirus has completed with posted results across pancreatic adenocarcinoma, ovarian c…