Biliary Tract Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-04-30Clinical Trial Update: Study of Combination Therapy of D07001-Softgel Capsules and Xeloda/TS-1 in Subjects With Advanced Biliary Tract Cancer [Phase 2, Phase 3]
A Phase 2/3 clinical trial update announcing recruitment for a combination of D07001-Softgel Capsules with Xeloda (capecitabine) or TS-1 in …
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CLINICAL_TRIALS research · 2025-04-22Clinical Trial Update: CDH17 CAR-T Therapy in Advanced Malignant Solid Tumors [EARLY_Phase 1]
An early-phase trial evaluating CDH17-targeted CAR-T cell therapy for advanced malignant solid tumors, including biliary tract cancer, color…
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CLINICAL_TRIALS research · 2025-04-20Clinical Trial Update: A Study of CTX-009 in Combination With Paclitaxel in Adult Patients With Unresectable Advanced, Metastatic or Recurrent Biliary Tract Cancers (COMPANION-002) [Phase 2, Phase 3]
Clinical trial update for COMPANION-002 evaluating CTX-009 in combination with Paclitaxel in adults with unresectable or metastatic biliary …
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CLINICAL_TRIALS research · 2025-04-09Clinical Trial Update: Oncolytic Virus H101 Combined With Lenvatinib Plus Toripalimab Compared With FOLFOX in Patients With Advanced Biliary Tract Cancer (OPTIONS-06) [Phase 2]
Phase 2 clinical trial evaluating the combination of H101 oncolytic virus with lenvatinib and toripalimab versus FOLFOX in patients with adv…
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CLINICAL_TRIALS research · 2025-04-06Clinical Trial Update: Extracellular RNA Markers of Liver Disease and Cancer
This ClinicalTrials.gov update reports on a Mayo Clinic-sponsored study investigating extracellular RNA markers in liver disease and cancer,…
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CLINICAL_TRIALS research · 2025-04-02Clinical Trial Update: A Study of HRS-4642 Monotherapy or in Combination With Adebrelimab in the Treatment of Advanced Biliary Tract Tumors. [Phase 2]
Phase 2 clinical trial evaluating HRS-4642 as monotherapy or in combination with Adebrelimab for advanced biliary tract tumors; currently re…
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CLINICAL_TRIALS research · 2025-03-30Clinical Trial Update: Study of TU2218 in Combination With KEYTRUDA®(Pembrolizumab) in Patients With Advanced Solid Tumors [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating TU2218 in combination with pembrolizumab (Keytruda) in patients with advanced solid tumors is currentl…
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CLINICAL_TRIALS research · 2025-03-30Clinical Trial Update: Neoadjuvant Tislelizumab, Gemcitabine, Cisplatin and S-1 for Resectable High-risk Cholangiocarcinoma [Phase 2]
This clinical trial update describes a Phase 2 neoadjuvant regimen of tislelizumab, gemcitabine, cisplatin, and S-1 for resectable high-risk…
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CLINICAL_TRIALS research · 2025-03-06Clinical Trial Update: A Clinical Study of SHR-A1811 in the Treatment of HER2-positive Locally Advanced or Metastatic Biliary Tract Cancer [Phase 2]
Phase 2 clinical trial evaluating SHR-A1811 for HER2-positive biliary tract cancer (locally advanced or metastatic) is currently recruiting.
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CLINICAL_TRIALS research · 2025-02-17Clinical Trial Update: CisPlatin plUs Gemcitabine and Nabpaclitaxel (GAP) as pReoperative Chemotherapy Versus Immediate Resection in patIents With resecTable BiliarY Tract Cancers (BTC) at High Risk for Recurrence [Phase 2, Phase 3]
Clinical trial update for a Phase 2/3 study evaluating preoperative Cisplatin, Gemcitabine, and Nab-paclitaxel (GAP) versus immediate resect…
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CLINICAL_TRIALS research · 2025-02-11Clinical Trial Update: Phase I/II Clinical Study to Evaluate VB15010 Tablets in Patients With Advanced Solid Tumors [Phase 1, Phase 2]
Phase I/II trial update for VB15010 tablets in advanced solid tumors; the study is currently recruiting across multiple cancer types.
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CLINICAL_TRIALS research · 2025-02-11Clinical Trial Update: Ambispective Cohort Study of Precision Medicine for Primary Hepatobiliary Cancer Based on Next-generation Sequencing
This clinical trial update describes an Ambispective Cohort Study using next-generation sequencing-guided precision medicine for primary hep…
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CLINICAL_TRIALS research · 2025-02-07Clinical Trial Update: XNW27011 Study of Advanced Solid Tumor Subjects Who Failed Standard Therapies. [Phase 1, Phase 2]
Clinical trial update indicating an early-phase study of XNW27011 for multiple advanced solid tumors is currently recruiting.
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CLINICAL_TRIALS research · 2025-02-05Clinical Trial Update: First-line Trastuzumab, Gemcitabine, Cisplatin and Nivolumab in Advanced HER2- Positive Biliary Tract Cancer: a Multicenter, Open-label, Single-arm Phase Ib/II Trial (HERBOT) [Phase 1, Phase 2]
A multicenter, open-label Phase Ib/II trial evaluating first-line trastuzumab with gemcitabine and cisplatin plus nivolumab in HER2-positive…
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CLINICAL_TRIALS research · 2025-01-28Clinical Trial Update: Donafenib Combined With Capecitabine for Postoperative Adjuvant Therapy of Biliary Malignant Tumors With High-risk Recurrence Risk [Phase 2]
Phase 2 trial evaluating donafenib in combination with capecitabine as postoperative adjuvant therapy for biliary tract cancer with high rec…
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CLINICAL_TRIALS research · 2025-01-28Clinical Trial Update: Olaparib With or Without Durvalumab for DDR Gene Mutated Biliary Tract Cancer Following Platinum-based Chemotherapy [Phase 2]
Phase 2 clinical trial investigating olaparib with or without durvalumab for biliary tract cancer with DNA damage repair mutations after pla…
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CLINICAL_TRIALS research · 2025-01-28Clinical Trial Update: A Prospective Cohort Study of Patients with Hepatobiliary Cancer Treated with Immune Checkpoint Inhibitors
This is a prospective cohort study evaluating immune checkpoint inhibitors in hepatobiliary cancers. The trial is currently active but not r…
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CLINICAL_TRIALS research · 2024-12-30Clinical Trial Update: Circulating Tumor Mitochondrial DNA (ct-mtDNA) As a Biomarker for Biliary Tract Cancer Recurrence Surveillance
A clinical trial is investigating whether circulating tumor mitochondrial DNA can serve as a biomarker to monitor recurrence in biliary trac…
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CLINICAL_TRIALS research · 2024-12-27Clinical Trial Update: Adebrelimab Combined with Apatinib and Gemcitabine and Cisplatin (GP) First-line Treatment for Unresectable Biliary Tract Carcinoma [Phase 2]
Phase 2 trial evaluating the combination of Adebrelimab with Apatinib and Gemcitabine/Cisplatin as first-line therapy for unresectable bilia…
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CLINICAL_TRIALS research · 2024-12-16Clinical Trial Update: A Single-arm, Open-label, Prospective Clinical Study of Surufatinib Combined With Immunotherapy and Chemotherapy for Unresectable or Metastatic Biliary Tract Cancer. [Phase 2]
A Phase 2, single-arm, open-label trial examining surufatinib in combination with immunotherapy and chemotherapy for unresectable or metasta…
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CLINICAL_TRIALS research · 2024-12-12Clinical Trial Update: Diagnostic Value of Next-Generation Sequencing Analysis in Biliary Tract Tumours [NA]
This clinical trial registry entry describes a study evaluating the diagnostic value of next-generation sequencing analysis in biliary tract…
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CLINICAL_TRIALS research · 2024-11-27Clinical Trial Update: Phase Ⅱ Clinical Study of Surufatinib Combined With Gemcitabine and Cisplatin Plus Durvalumab/Pembrolizumab Regimen in the Treatment of Advanced Biliary Tract Cancer [Phase 2]
Phase II trial evaluates a combination of surufatinib with gemcitabine, cisplatin, and durvalumab or pembrolizumab for advanced biliary trac…
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CLINICAL_TRIALS research · 2024-11-21Clinical Trial Update: Irinotecan Liposomes +5-FU/LV Versus Capecitabine in Patients of Recurrence After Resection of Resectable BTC [Phase 2]
Phase 2 trial comparing liposomal irinotecan plus 5-FU/leucovorin versus capecitabine in biliary tract cancer patients with recurrence after…
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CLINICAL_TRIALS research · 2024-10-26Clinical Trial Update: A Study of Tumor-Treating Fields in Combination With Durvalumab and Gemcitabine/Cisplatin in Biliary Tract Cancers [NA]
This update reports an ongoing clinical trial evaluating tumor-treating fields in combination with durvalumab and gemcitabine/cisplatin for …
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CLINICAL_TRIALS research · 2024-10-24Clinical Trial Update: Endoscopic Retrograde Cholangiopancreatography With Radiofrequency Ablation (ERCP-RFA) Combined With Envafolimab and Surufatinib Sequential Therapy for Unresectable Biliary Tract Carcinoma [Phase 2]
Phase 2 clinical trial evaluating ERCP-RFA followed by sequential therapy with envafolimab and surufatinib for unresectable biliary tract ca…