Biliary Tract Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03) [Phase 2]
AstraZeneca's Dato-DXd is being studied as a single agent and in combination with other anti-cancer drugs in an ongoing Phase 2 trial for ad…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Role of ctDNA in Genetic Profiling & Outcomes for Advanced BTC
This is a ClinicalTrials.gov study evaluating ctDNA-based genetic profiling in advanced biliary tract cancer. The trial is currently recruit…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: ctDNA in Genetic Profiling and Clinical Outcomes of Advanced Biliary Tract Cancer
This CHA University-led clinical trial is evaluating ctDNA-based genetic profiling and its association with clinical outcomes in advanced bi…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Investigation of Predictive Biomarkers in Patients With Advanced BTC Treated With Lenvatinib Plus Pembrolizumab
Clinical trial update describing investigation of predictive biomarkers in patients with advanced biliary tract cancer treated with lenvatin…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Vebotolimab Combined With Ptorlimab for EGFR-positive Refractory Advanced Biliary Tract Malignancies [Phase 2]
A Phase 2 clinical trial evaluating the combination of vebotolimab and Ptorlimab for EGFR-positive advanced biliary tract cancers is not yet…
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CLINICAL_TRIALS research · 2026-03-17Clinical Trial Update: A Study of Rilvegostomig or Durvalumab Plus Chemotherapy for First-Line Treatment of Biliary Tract Cancer (ARTEMIDE-Biliary02) [Phase 3]
This document reports an ongoing Phase 3 trial evaluating rilvegostomig or durvalumab plus chemotherapy as first-line treatment for biliary …
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: A Clinical Trial of LBL-024 Combination Drug in Patients With Advanced Solid Tumours[Substudy 02(BTC&HCC)] [Phase 2]
Phase 2 clinical study of LBL-024 in combination therapy for advanced solid tumors is currently recruiting, with substudy focusing on biliar…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: TRACE-BTC. Relation of Biomarkers and Patients Reported Quality of Life to Outcomes in Patients With Biliary Tract Cancer: a Real- World Cohort
The TRACE-BTC study is a real-world cohort investigation examining how biomarkers and patient-reported quality of life relate to outcomes in…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Study of TJ033721 (Givastomig) in Subjects With Advanced or Metastatic Solid Tumors [Phase 1]
Phase 1 trial evaluating TJ033721 (Givastomig) in adults with advanced or metastatic solid tumors; the study is currently recruiting and inc…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: A Study of AK130 in Combination With AK112 for the Treatment of Advanced Biliary Tract Cancer [Phase 1, Phase 2]
Clinical trial update describing a Phase 1/Phase 2 study of AK130 in combination with AK112 for advanced biliary tract cancer, currently rec…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Testing Mitazalimab in Combination With Standard Chemotherapy in Immunotherapy Resistant Advanced Biliary Tract Cancers [Phase 2, Phase 3]
A clinical trial update indicates Mitazalimab is being tested in combination with standard chemotherapy for immunotherapy-resistant advanced…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Ligufalimab and Cadonilimab in Advanced Liver Cancers [Phase 2]
Phase 2 clinical trial update on Ligufalimab and Cadonilimab in advanced hepatocellular carcinoma and biliary tract cancer, currently recrui…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Combination Immunotherapy in Rare Cancers Under InvesTigation [Phase 2]
This is a Phase 2 trial update describing a combination immunotherapy study for rare cancers; the trial is currently active but not recruiti…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: A Post-marketing Observational Study of Tasfygo in Participants With Unresectable Biliary Tract Cancer With Fibroblast Growth Factor Receptor 2 (FGFR2) Fusion Gene Positivity Who Progressed After Chemotherapy
This document describes a post-marketing observational study of Tasfygo for unresectable biliary tract cancer with FGFR2 fusion after chemot…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: Gemcitabine, Cisplatin, Nab-paclitaxel (GAP) and Cemiplimab for Locally Advanced Biliary Tract Cancer (BTC) [Phase 2]
Phase 2 clinical trial evaluating Gemcitabine, Cisplatin, Nab-paclitaxel (GAP) with Cemiplimab for locally advanced biliary tract cancer; cu…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Frailty Scales for Predicting Chemotherapy Toxicity in Older Adults With Gastrointestinal Cancers
Completed clinical trial evaluating frailty scales to predict chemotherapy toxicity in older adults with gastrointestinal cancers.
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Trifluridine/Tipiracil + Oxaliplatin in Participants With Advanced or Metastatic Biliary Tract Cancer [Phase 2]
Phase 2 clinical trial evaluating the combination of trifluridine/tipiracil with oxaliplatin for advanced or metastatic biliary tract cancer…
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: Candonilimab in Combination With LM-302 for Claudin 18.2 Positive-advanced Biliary Tract Cancer After Failure of Standard of Chemotherapy and PD1/PD-L1 Antibody [Phase 1, Phase 2]
Clinical trial update for a phase 1/2 study of Candonilimab in combination with LM-302 for Claudin 18.2 positive advanced biliary tract canc…
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: A Phase 1/1B Study of ST-01156, a Small Molecule RBM39 Degrader, in Patients With Advanced Solid Malignancies [Phase 1]
This clinical trial update describes a Phase 1/1B study of ST-01156, a small-molecule RBM39 degrader, in patients with advanced solid tumors…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: AZD0901 in Participants With Advanced Solid Tumours Expressing Claudin18.2 [Phase 2]
Phase 2 clinical trial evaluating AZD0901 in advanced solid tumours expressing Claudin18.2 is currently recruiting, including gastric cancer…
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CLINICAL_TRIALS research · 2026-02-11Clinical Trial Update: A Prospective Observational Study of First-Line Systemic Therapy Combined With Celiac Plexus Blockade for Advanced Biliopancreatic Cancer With Pain
An observational study evaluating first-line systemic therapy combined with celiac plexus blockade for pain in advanced biliary tract cancer…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: A Phase III Study of SHR-8068 in Combination With Adebrelimab and Platinum-Containing Chemotherapy Versus Durvalumab in Combination With Platinum-Containing Chemotherapy as First-line Treatment for Advanced Biliary Tract Cancer (BTC) [Phase 3]
A Phase 3 study evaluating SHR-8068 plus Adebrelimab and platinum-containing chemotherapy versus Durvalumab plus platinum-containing chemoth…
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: NAPOLI-2: Fluorouracil, Leucovorin, and Nanoliposomal Irinotecan in Biliary Cancer [Phase 2]
Phase 2 clinical trial update evaluating nanoliposomal irinotecan with fluorouracil and leucovorin in advanced biliary tract cancer.
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Study of Gemcitabine, Cisplatin, AB680 and AB122 During First Line Treatment of Advanced Biliary Tract Cancers (QUIC) [Phase 2]
Phase 2 clinical trial assessing a four-drug combination (gemcitabine, cisplatin, AB680, AB122) as first-line therapy for advanced biliary t…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: The Purpose of This Trial is to Determine if Regorafenib Plus Durvalumab (MEDI4736) is Safe and Effective in Treatment of Chemo Refractory Advanced Biliary Tract Cancers [Phase 1, Phase 2]
A Phase 1/2 trial is evaluating the safety and efficacy of combining regorafenib with durvalumab (MEDI4736) in chemo-refractory advanced bil…