Basal Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-05-08Clinical Trial Update: A Study of Vismodegib With Surgery in Participants With Previously Untreated Basal Cell Carcinoma [Phase 2]
A Phase 2 study evaluating vismodegib in combination with surgery for previously untreated basal cell carcinoma was terminated; results were…
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CLINICAL_TRIALS withdrawal · 2017-05-05Clinical Trial Update: Efficacy, Safety and Tolerability of Topically Applied LDE225 Cream (Hedgehog Pathway Inhibitor) in Adult Patients With Nevoid Basal Cell Carcinoma Syndrome (NBCCS) [Phase 2, Phase 3]
A Phase 2/3 trial evaluating topical Hedgehog pathway inhibitor LDE225 cream for adults with nevoid basal cell carcinoma syndrome (NBCCS) an…
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CLINICAL_TRIALS trial_result · 2017-03-31Clinical Trial Update: Set-back Suture Versus Traditional Vertical Mattress Suture [NA]
A completed clinical trial comparing set-back suture to traditional vertical mattress suture for surgical closure in skin cancer patients. T…
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CLINICAL_TRIALS trial_result · 2017-03-17Clinical Trial Update: CSP #562 - The VA Keratinocyte Carcinoma Chemoprevention Trial [Phase 4]
Phase 4 trial update for a keratinocyte carcinoma chemoprevention study (VA CSP #562) has completed with results posted.
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CLINICAL_TRIALS trial_result · 2017-03-14Clinical Trial Update: DMSO-PDT of BCC - A 6 Year Follow up
This update reports a six-year follow-up of dimethyl sulfoxide-assisted photodynamic therapy for basal cell carcinoma. The trial status is c…
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FDA approval · 2016-11-02FDA Approved: ERIVEDGE — Supplemental Application (Genentech, Inc.)
FDA approved a supplemental application for ERIVEDGE (vismodegib) filed by Genentech, Inc., expanding/ updating the drug's regulatory status…
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CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: Pilot LDE225 in Locally Advanced or Metastatic BCC + Previously Tx Non-LDE225 Smoothened Inhibitors [NA]
Pilot study of LDE225 (sonidegib) in locally advanced or metastatic basal cell carcinoma previously treated with non-LDE225 Smoothened inhib…
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CLINICAL_TRIALS trial_result · 2016-10-19Clinical Trial Update: Study of Electronic Brachytherapy for Cutaneous Basal Cell Carcinoma [NA]
This clinical trial evaluated electronic brachytherapy for cutaneous basal cell carcinoma and has completed. The sponsor is Instituto de Inv…
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CLINICAL_TRIALS trial_result · 2016-09-23Clinical Trial Update: Topical Sirolimus in Patients With Basal Cell Nevus Syndrome and in Healthy Participants [Phase 1]
A Phase 1 trial evaluating topical sirolimus in patients with Basal Cell Nevus Syndrome and in healthy participants has completed, reporting…
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CLINICAL_TRIALS research · 2016-09-15Clinical Trial Update: Optical Imaging for Preoperative Delineation of Nonmelanoma Skin Cancers
Clinical trial update describing optical imaging to help delineate nonmelanoma skin cancers (basal cell and squamous cell carcinomas) preope…
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FDA approval · 2016-08-29FDA Approved: IMIQUIMOD — Supplemental Application (Sun Pharmaceutical Industries, Inc.)
The FDA approved a supplemental application for Imiquimod submitted by Sun Pharmaceutical Industries. This action typically updates labeling…
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CLINICAL_TRIALS trial_result · 2016-08-04Clinical Trial Update: A Study of Two Vismodegib Regimens in Participants With Multiple Basal Cell Carcinomas [Phase 2]
Phase 2 trial update evaluating two vismodegib regimens in participants with multiple basal cell carcinomas; results posted after completion…
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CLINICAL_TRIALS trial_result · 2016-07-19Clinical Trial Update: Debulking Effect of Curretage on Basal Cell Carcinomas - a Histological Assessment. [NA]
A completed clinical trial examining how curettage affects histological debulking of basal cell carcinomas.
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CLINICAL_TRIALS trial_result · 2016-05-18Clinical Trial Update: Topical Green Tea Ointment in Treatment of Superficial Skin Cancer [Phase 2, Phase 3]
This clinical trial update reports completion of Phase 2 and Phase 3 trials evaluating a topical green tea ointment for basal cell carcinoma…
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FDA approval · 2016-05-12FDA Approved: ODOMZO — Supplemental Application (Sun Pharmaceutical Industries, Inc.)
FDA approved a supplemental application for Sun Pharmaceutical's ODOMZO (sonidegib) submitted by Sun Pharmaceutical Industries, Inc.
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CLINICAL_TRIALS trial_result · 2016-04-13Clinical Trial Update: One-stop-shop Study for Treatment of Basal Cell Carcinoma Using Reflectance Confocal Microscopy [NA]
The document notes the completion of a clinical trial evaluating a one-stop-shop treatment approach for basal cell carcinoma using reflectan…
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CLINICAL_TRIALS trial_result · 2016-04-04Clinical Trial Update: Safety, Tolerability and Performance of SmartMatrix Dermal Replacement Scaffold [Phase 1, Phase 2]
This trial update reports termination of a Phase 1/2 study evaluating the SmartMatrix Dermal Replacement Scaffold for basal cell carcinoma a…
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CLINICAL_TRIALS trial_result · 2016-03-15Clinical Trial Update: Investigation of the Safety and Tolerability of BSCT (Anti-nf-P2X7) 10% Ointment [Phase 1]
Phase 1 study assessing safety and tolerability of a 10% BSCT ointment targeting nf-P2X7 in basal cell carcinoma; study completed with resul…
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CLINICAL_TRIALS trial_result · 2016-02-15Clinical Trial Update: To Determine the Maximum Tolerated Dose Level (MTD) of PEP005 Topical Gel in Patients With sBCC [Phase 2]
A Phase 2 study concluded to determine the maximum tolerated dose of PEP005 topical gel in patients with superficial basal cell carcinoma.
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CLINICAL_TRIALS trial_result · 2016-02-11Clinical Trial Update: Topical Tazarotene in Treating Patients With Basal Cell Skin Cancer and Basal Cell Nevus Syndrome on the Chest and Back [Phase 2]
Phase 2 clinical trial evaluating topical tazarotene for basal cell carcinoma and basal cell nevus syndrome on the chest and back has comple…
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CLINICAL_TRIALS trial_result · 2016-02-11Clinical Trial Update: Topical Tazarotene in Treating Patients With Basal Cell Skin Cancer and Basal Cell Nevus Syndrome on the Face [Phase 2]
Phase 2 trial of topical tazarotene for basal cell skin cancer and basal cell nevus syndrome on the face has completed with results posted.
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CLINICAL_TRIALS trial_result · 2016-02-05Clinical Trial Update: Long Term Prospective Study Evaluating Effectiveness of Narrow Margins for Low-Risk Head and Neck Basal Cell Carcinomas [NA]
This clinical trial update outlines a long-term prospective study assessing the effectiveness of narrow margins for low-risk head and neck b…
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CLINICAL_TRIALS trial_result · 2015-12-18Clinical Trial Update: Multi-Wavelength and Coherence Confocal Reflectance Microscopy of Pigmented and Non-Pigmented Lesions on the Skin In-Vivo
A completed clinical trial from Memorial Sloan Kettering Cancer Center evaluated multi-wavelength coherence confocal reflectance microscopy …
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CLINICAL_TRIALS trial_result · 2015-11-23Clinical Trial Update: A Phase II Study of Efficacy and Safety in Patients With Locally Advanced or Metastatic Basal Cell Carcinoma [Phase 2]
A Phase II study evaluating the efficacy and safety of a treatment in patients with locally advanced or metastatic basal cell carcinoma has …
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CLINICAL_TRIALS trial_result · 2015-10-30Clinical Trial Update: To Evaluate the Safety, Local Tolerability, PK and PD of LDE225 on Sporadic Superficial and Nodular Skin Basal Cell Carcinomas (sBCC) [Phase 2]
Phase 2 trial of LDE225 (sonidegib) evaluating safety, local tolerability, pharmacokinetics and pharmacodynamics in sporadic superficial and…