Bacteremia
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CLINICAL_TRIALS trial_result · 2012-08-07Clinical Trial Update: Linezolid in the Treatment of Hemodialysis Patients With Catheter-Related Gram-Positive Bloodstream Infections [Phase 3]
A Phase 3 trial evaluating Linezolid for catheter-related Gram-positive bloodstream infections in hemodialysis patients was terminated, with…
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FDA approval · 2012-04-09FDA Approved: VANCOMYCIN HYDROCHLORIDE — Original Application (Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc.)
FDA approved the original ANDA for vancomycin hydrochloride from Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals Inc., enabling a g…
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CLINICAL_TRIALS trial_result · 2012-03-27Clinical Trial Update: Disease Burden of Pneumonia, Meningitis and Bacteremia Among Children in Japan: Pneumonet Japan
Pfizer-sponsored trial update reporting on the disease burden of pneumococcal disease (pneumonia, meningitis, and bacteremia) among children…
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CLINICAL_TRIALS trial_result · 2012-01-05Clinical Trial Update: Ethanol Lock for the Salvage of Infected Long-term Vascular Access [Phase 3]
Phase 3 trial update evaluating ethanol lock therapy to salvage infected long-term vascular access in patients with bacteremia; current stat…
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CLINICAL_TRIALS trial_result · 2011-10-27Clinical Trial Update: Colombia Epidemiologic Surveillance Study
Pfizer-sponsored Colombia Epidemiologic Surveillance Study has been terminated. The study investigated Pneumonia, Meningitis, Bacteremia, an…
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CLINICAL_TRIALS withdrawal · 2011-09-28Clinical Trial Update: Safety and Efficacy Study of CUBICIN (Daptomycin) Under Conditions of Actual Use
A study evaluating the safety and efficacy of Cubicin (daptomycin) under real-use conditions has been withdrawn.
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CLINICAL_TRIALS trial_result · 2011-08-05Clinical Trial Update: The Value of sTREM-1, PCT, and CRP as Markers for the Detection of Sepsis and Bacteremia Among Patients With a FUO
This completed clinical trial evaluated whether the biomarkers sTREM-1, procalcitonin (PCT), and C-reactive protein (CRP) can detect sepsis …
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CLINICAL_TRIALS trial_result · 2011-07-26Clinical Trial Update: Increasing the Yield of Blood Cultures in Neonates [NA]
A completed clinical trial evaluating methods to increase the yield of blood cultures in neonates.
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CLINICAL_TRIALS research · 2011-07-12Clinical Trial Update: Recurrent ESBL-producing Enterobacteriaceae Bacteremia: Risk Factor, Molecular Character and Susceptibility Change
This clinical trial update discusses recurrent ESBL-producing Enterobacteriaceae bacteremia, focusing on risk factors, molecular characteris…
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FDA approval · 2011-06-30FDA Approved: NAFCILLIN — Original Application (Fresenius Kabi USA, LLC)
FDA approved the original application for Nafcillin sodium (NAFCILLIN SODIUM) as a generic injectable antibiotic from Fresenius Kabi USA, LL…
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CLINICAL_TRIALS trial_result · 2011-06-15Clinical Trial Update: A Study of MK-3009 in Japanese Patients With Skin or Blood Stream Infections Caused by Methicillin-resistant Staphylococcus Aureus (MK-3009-002) [Phase 3]
Phase 3 clinical trial update for MK-3009 in Japanese patients with MRSA-related skin and bloodstream infections; results for MK-3009-002 we…
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CLINICAL_TRIALS trial_result · 2011-05-18Clinical Trial Update: Procalcitonin Level and Kinetics in Children With Bacterial Infections
A completed pediatric trial evaluating procalcitonin levels and their kinetics in children with various bacterial infections to explore pote…
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FDA approval · 2011-04-20FDA Approved: NAFCILLIN — Original Application (Athenex Pharmaceutical Division, LLC.)
FDA approves the original application for Nafcillin (nafcillin sodium) as a generic antibiotic from Athenex Pharmaceutical Division, LLC.
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CLINICAL_TRIALS trial_result · 2011-02-23Clinical Trial Update: Retrospective Evaluation of Safety and Efficacy of Daptomycin Used in Patients With Serious Gram-positive Infections
Retrospective evaluation of the safety and efficacy of daptomycin in patients with serious Gram-positive infections, including bacteremia an…
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CLINICAL_TRIALS trial_result · 2010-09-10Clinical Trial Update: Rapid Test to Detect Staphylococcus Aureus in Blood and Wound Infections
Completed clinical trial assessing a rapid diagnostic test for detecting Staphylococcus aureus in blood and wound infections.
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CLINICAL_TRIALS trial_result · 2010-08-18Clinical Trial Update: Prospective Study Into the Performance of the MicroPhage S. Aureus/MSSA/MRSA Test Direct From Blood Culture Positives
A prospective study evaluating the performance of the MicroPhage S. aureus/MSSA/MRSA test directly on blood culture positives. The trial has…
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CLINICAL_TRIALS trial_result · 2010-07-28Clinical Trial Update: Daptomycin Pharmacokinetics in Continuous Veno-venous Hemodiafiltration [Phase 2]
Phase 2 clinical trial update examining the pharmacokinetics of daptomycin in patients with bacteremia undergoing continuous veno-venous hem…
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CLINICAL_TRIALS trial_result · 2010-02-05Clinical Trial Update: Rate of Catheter Colonization and Risk of Bloodstream Infection During Use of Two Different Central Venous Catheters (CVC) [Phase 4]
A Phase 4 trial comparing two central venous catheters assessed catheter colonization rates and the risk of bloodstream infection; the study…
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CLINICAL_TRIALS trial_result · 2009-12-24Clinical Trial Update: The Impact of Material on Microbiota in Association With Tongue and Lip Piercing
The study analyzes how different piercing materials affect oral microbiota and the potential risk of bacteremia from tongue and lip piercing…
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CLINICAL_TRIALS trial_result · 2009-09-25Clinical Trial Update: Alcohol Locks for the Prevention of Tunneled Catheter-related Infections [Phase 2, Phase 3]
Clinical trial update on completed Phase 2 and Phase 3 studies of alcohol lock solutions to prevent tunneled catheter-related infections lea…
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CLINICAL_TRIALS trial_result · 2009-09-14Clinical Trial Update: Antibiotic Treatment for Infections of Short Term In-dwelling Vascular Catheters Due to Gram Positive Bacteria [Phase 3]
Pfizer-conducted Phase 3 trial evaluating an antibiotic for catheter-related bloodstream infections caused by Gram-positive bacteria has com…
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CLINICAL_TRIALS research · 2009-07-03Clinical Trial Update: Bacteremia in Intensive Care Unit (ICU)
Clinical trial update on bacteremia and sepsis in ICU patients, with emphasis on Toll-Like Receptors (TLRs); no status information is provid…
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CLINICAL_TRIALS other · 2009-03-17Clinical Trial Update: Central Venous Catheter Lock Solution [NA]
This entry notes an ongoing clinical trial from University Medical Center Tuzla evaluating a central venous catheter lock solution for bacte…
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CLINICAL_TRIALS trial_result · 2008-12-24Clinical Trial Update: MicroPhage S. Aureus / MSSA / MRSA Blood Culture Beta Trial
A completed beta trial by MicroPhage, Inc. evaluating phage therapy against Staphylococcus aureus bacteremia (MSSA/MRSA) using blood culture…
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CLINICAL_TRIALS trial_result · 2008-06-09Clinical Trial Update: Steady State Serum and Epithelial Lining Fluid (ELF) Antibiotics Concentrations Under Continous Infusion
The trial update reports steady-state antibiotic concentrations in serum and epithelial lining fluid during continuous infusion in patients …