B-cell Non-hodgkin Lymphoma
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CLINICAL_TRIALS research · 2025-11-05Clinical Trial Update: A Study of Anakinra to Prevent or Treat Severe Side Effects for Patients Receiving CAR-T Cell Therapy [Phase 2]
Phase 2 clinical trial evaluating anakinra to prevent or treat severe side effects in patients receiving CAR-T cell therapy; status is activ…
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CLINICAL_TRIALS research · 2025-11-04Clinical Trial Update: A Study of Radiation Therapy Before CAR T Cell Therapy for People With B Cell Lymphoma [Phase 1]
This clinical trial update describes a Phase 1 study evaluating radiation therapy before CAR T cell therapy for patients with B-cell non-Hod…
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CLINICAL_TRIALS trial_result · 2025-10-23Clinical Trial Update: Anakinra for the Prevention of Cytokine Release Syndrome and Neurotoxicity in Patients With B-Cell Non-Hodgkin Lymphoma Receiving CD19-Targeted CAR-T Cell Therapy [Phase 2]
A Phase 2 trial evaluating anakinra to prevent cytokine release syndrome and neurotoxicity in patients with B-cell non-Hodgkin lymphoma rece…
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CLINICAL_TRIALS research · 2025-10-16Clinical Trial Update: Loncastuximab Tesirine for the Treatment of Relapsed or Refractory B-Cell Malignancies [Phase 2]
This update reports a Phase 2 trial of loncastuximab tesirine for relapsed or refractory B-cell malignancies that is currently recruiting, i…
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CLINICAL_TRIALS trial_result · 2025-10-15Clinical Trial Update: Study of Acalabrutinib Alone or in Combination Therapy in Subjects With B-cell Non-Hodgkin Lymphoma [Phase 1, Phase 2]
Acalabrutinib is being studied in Phase 1/2 as a single agent or in combination therapy for B-cell non-Hodgkin lymphoma, with results posted…
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CLINICAL_TRIALS trial_result · 2025-10-15Clinical Trial Update: A Study to Assess the Anti-Tumor Activity and Safety of Odronextamab in Adult Patients With B-cell Non-Hodgkin Lymphoma Who Have Been Previously Treated With Other Cancer Therapies [Phase 2]
Phase 2 clinical trial update evaluating the anti-tumor activity and safety of odronextamab in adults with B-cell non-Hodgkin lymphoma who h…
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CLINICAL_TRIALS trial_result · 2025-10-08Clinical Trial Update: Acalabrutinib and Anti-CD19 CAR T-cell Therapy for the Treatment of B-cell Lymphoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating the combination of acalabrutinib with anti-CD19 CAR T-cell therapy for various B-cell lymphomas, in…
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CLINICAL_TRIALS research · 2025-10-06Clinical Trial Update: Geriatric Assessment Guided Interventions to Accelerate Functional Recovery After CAR-T Therapy for Patients 60 Years and Older With B-cell Non-Hodgkin Lymphoma or Multiple Myeloma, GOCART Study [Phase 2]
Phase 2 clinical trial evaluating geriatric assessment-guided interventions to accelerate functional recovery after CAR-T therapy in patient…
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CLINICAL_TRIALS trial_result · 2025-10-01Clinical Trial Update: IKS03 in Patients With Advanced B Cell Non-Hodgkin Lymphomas [Phase 1]
Phase 1 study update for IKS03 in advanced B-cell non-Hodgkin lymphomas is currently recruiting across multiple subtypes including diffuse l…
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CLINICAL_TRIALS trial_result · 2025-09-30Clinical Trial Update: Modified Immune Cells (AFM13-NK) and A Monoclonal Antibody (AFM13) in Treating Patients With Recurrent or Refractory CD30 Positive Hodgkin or Non-Hodgkin Lymphomas [Phase 1, Phase 2]
This is a completed Phase 1/2 clinical trial from MD Anderson evaluating AFM13 and AFM13-NK in patients with recurrent or refractory CD30-po…
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CLINICAL_TRIALS research · 2025-09-30Clinical Trial Update: Exploratory Study on the Efficacy of Zebutinib as Maintenance Therapy Following CAR-T Cell Therapy in Patients With Non-Hodgkin B-Cell Lymphoma
Exploratory study evaluating Zebutinib as maintenance therapy after CAR-T treatment in patients with B-cell non-Hodgkin lymphoma; recruitmen…
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: Immunotherapy for High Risk/Relapsed CD19+ Acute Lymphoblastic Leukaemia, B-cell Non-Hodgkin's Lymphoma (B-NHL) and Chronic Lymphocytic Leukaemia (CLL)/ Small Lymphocytic Lymphoma (SLL) Using CAR T-cells to Target CD19 [Phase 1]
A Phase 1 clinical trial update describing CD19-targeted CAR T-cell immunotherapy for high-risk or relapsed CD19+ acute lymphoblastic leukem…
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: Decitabine-primed Tandem CD19/CD20 CAR T Cells Treatment in r/r B-NHL [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating decitabine-primed tandem CD19/CD20 CAR T cells in relapsed and refractory B-cell non-Hodgkin lymphoma …
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: Clinical Study of U01（ssCART-19） in Patients With B-Cell Lymphoma [Phase 1]
A Phase 1 study of U01 (ssCART-19) for B-cell lymphoma is currently recruiting.
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CLINICAL_TRIALS research · 2025-09-15Clinical Trial Update: An Early Phase Study of Venetoclax, Lenalidomide, and Rituximab/Hyaluronidase in Slow-Growing Lymphomas That Have Come Back After Treatment or Have Not Responded to Treatment [Phase 1]
Early-phase trial evaluating a three-drug combination (venetoclax, lenalidomide, and rituximab with hyaluronidase) in relapsed or refractory…
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CLINICAL_TRIALS trial_result · 2025-08-26Clinical Trial Update: Rituximab and Combination Chemotherapy With or Without Radiation Therapy in Treating Patients With B-Cell Non-Hodgkin's Lymphoma [Phase 3]
Phase 3 trial evaluating Rituximab plus chemotherapy, with or without radiation therapy, in patients with B-cell non-Hodgkin lymphoma; trial…
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CLINICAL_TRIALS trial_result · 2025-08-26Clinical Trial Update: CD19 CAR T-Cell Therapy for R/R Non-Hodgkin Lymphoma and Acute Lymphoblastic Leukemia [Phase 1]
Phase 1 trial of CD19 CAR T-cell therapy for relapsed/refractory B-cell non-Hodgkin lymphoma and B-cell acute lymphoblastic leukemia has com…
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CLINICAL_TRIALS research · 2025-08-24Clinical Trial Update: Study Evaluating UCART20x22 in B-Cell Non-Hodgkin Lymphoma [Phase 1, Phase 2]
A status update on UCART20x22 in B-cell Non-Hodgkin Lymphoma showing Phase 1/Phase 2 trials currently recruiting.
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CLINICAL_TRIALS research · 2025-08-21Clinical Trial Update: A Dose Escalating Study of CD19/CD22/BCMA CAR-T Therapy in Relapsed or Refractory B Cell Non-Hodgkin Lymphoma(NHL) [EARLY_Phase 1]
This is an early Phase 1 dose-escalation trial evaluating a combined CD19/CD22/BCMA CAR-T therapy for relapsed or refractory B-cell non-Hodg…
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CLINICAL_TRIALS research · 2025-08-21Clinical Trial Update: JS203 Combination Regimens in B-Cell Non-Hodgkin's Lymphoma [Phase 2]
Phase 2 clinical trial evaluating JS203 combination regimens for B-cell non-Hodgkin's lymphoma is currently recruiting.
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CLINICAL_TRIALS research · 2025-08-20Clinical Trial Update: Targeting CD19/CD20 Dual-targeted Cell in Patients With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma [EARLY_Phase 1]
An early-phase 1 clinical trial evaluating a CD19/CD20 dual-targeted cellular therapy in relapsed/refractory B-cell non-Hodgkin lymphoma.
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CLINICAL_TRIALS trial_result · 2025-08-20Clinical Trial Update: Tailored Prednisone Reduction in Preventing Hyperglycemia in Participants With B-Cell Non-Hodgkin Lymphoma Receiving Combination Chemotherapy Treatment [Phase 2]
Phase 2 trial update evaluating tailored prednisone reduction to prevent hyperglycemia in patients with B-cell non-Hodgkin lymphoma undergoi…
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CLINICAL_TRIALS research · 2025-08-07Clinical Trial Update: T-Cell Therapy (EB103) in Adults With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma (NHL) [Phase 1, Phase 2]
An update on an ongoing Phase 1/2 clinical trial evaluating Estrella Biopharma's EB103 T-cell therapy in adults with relapsed/refractory B-c…
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: Fourth-gen CAR T Cells Targeting CD19/CD22 for Highly Resistant B-cell Lymphoma/Leukemia (PMBCL/CNS-BCL). [Phase 1, Phase 2]
This Clinical Trial Update describes a fourth-generation CD19/CD22 dual-targeting CAR T-cell therapy being evaluated in Phase 1/2 for highly…
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CLINICAL_TRIALS trial_result · 2025-07-18Clinical Trial Update: The Safety, Tolerability, and Efficacy of IBR900 Cell Injection in Relapsed/Refractory B-cell Non Hodgkin Lymphoma [Phase 1]
Phase 1 trial update evaluating the safety, tolerability, and potential efficacy of IBR900 cell injections in patients with relapsed or refr…