B-cell Non-hodgkin Lymphoma

CLINICAL_TRIALS trial_result · 2024-04-25

Clinical Trial Update: A Phase I Safety, PK and PD Study of KW-2478 in Patients With Multiple Myeloma, Chronic Lymphocytic Leukaemia or B-cell Non-Hodgkin's Lymphoma [Phase 1]

A Phase I safety, pharmacokinetic and pharmacodynamic study of KW-2478 in patients with multiple myeloma, chronic lymphocytic leukemia, or B…

CLINICAL_TRIALS trial_result · 2024-04-22

Clinical Trial Update: Pilot Study of Pembrolizumab Treatment for Disease Relapse After Allogeneic Stem Cell Transplantation [EARLY_Phase 1]

A phase 1 pilot trial evaluating pembrolizumab for relapse after allogeneic stem cell transplantation in patients with classical Hodgkin lym…

CLINICAL_TRIALS trial_result · 2023-07-06

Clinical Trial Update: TRAC Locus-inserted CD19-targeting STAR-T Cell Therapy in r/r B-NHL [Phase 1, Phase 2]

Clinical trial update for TRAC locus-inserted CD19-targeting STAR-T cell therapy in relapsed/refractory B-cell non-Hodgkin lymphoma (Phase 1…

CLINICAL_TRIALS trial_result · 2023-05-24

Clinical Trial Update: A Clinical Study of Injectable IMM0306 in Combination With Lenalidomide [Phase 1, Phase 2]

Trial update for an injectable IMM0306 in combination with lenalidomide for B-cell non-Hodgkin's lymphoma across Phase 1 and Phase 2.

CLINICAL_TRIALS trial_result · 2023-05-22

Clinical Trial Update: A Safety, Tolerability, Pharmacokinetics and Efficacy Study of GB261 in B-Cell NHL and CLL. [Phase 1, Phase 2]

A safety, tolerability, pharmacokinetics and efficacy study of GB261 in B-cell non-Hodgkin lymphoma and chronic lymphocytic leukemia is in P…

CLINICAL_TRIALS trial_result · 2023-04-18

Clinical Trial Update: Acalabrutinib With Rituximab and Lenalidomide in Relapsed/Refractory B-cell Non-Hodgkin Lymphoma [Phase 2]

Phase 2 trial evaluating acalabrutinib with rituximab and lenalidomide in relapsed/refractory B-cell non-Hodgkin lymphoma has completed.

CLINICAL_TRIALS trial_result · 2023-03-21

Clinical Trial Update: Bortezomib and Gemcitabine in Treating Patients With Relapsed B-Cell Non-Hodgkin Lymphoma [Phase 1, Phase 2]

Clinical trial update for bortezomib and gemcitabine in relapsed B-cell non-Hodgkin lymphoma (Phase 1/Phase 2) completed with results posted…

CLINICAL_TRIALS trial_result · 2023-02-24

Clinical Trial Update: Clinical Study of the Safety and Efficacy of the R/R B-NHL Regimen With BTK Inhibitor+Anti-CD19 CAR-T Cells [Phase 2]

A Phase 2 clinical trial assessing the safety and efficacy of a regimen combining BTK inhibitor with anti-CD19 CAR-T cells for relapsed/refr…

CLINICAL_TRIALS trial_result · 2023-02-09

Clinical Trial Update: Clinical Study of XPO-1 Inhibitors Plus CAR-T Cells in Relapsed Refractory B-cell Non-Hodgkin's Lymphoma [Phase 2]

Phase 2 clinical trial investigating XPO-1 inhibitors in combination with CAR-T cells for relapsed/refractory B-cell non-Hodgkin's lymphoma.

CLINICAL_TRIALS trial_result · 2023-01-31

Clinical Trial Update: Dose-escalation Study of Safety of PBCAR20A in Subjects With r/r NHL or r/r CLL/SLL [Phase 1, Phase 2]

Dose-escalation early-stage trial assessing safety of PBCAR20A in relapsed/refractory Non-Hodgkin's Lymphoma and relapsed/refractory Chronic…

CLINICAL_TRIALS trial_result · 2022-12-23

Clinical Trial Update: A Phase II Study of Allo-HCT for B-Cell NHL Using Zevalin, Fludarabine and Melphalan [Phase 2]

Phase II trial evaluating allogeneic hematopoietic cell transplantation for B-cell non-Hodgkin lymphoma using Zevalin, fludarabine, and melp…

CLINICAL_TRIALS trial_result · 2022-08-22

Clinical Trial Update: Safety Analysis of Intravenous Rapid Infusion of Obinutuzumab in Patients With B-cell Non-Hodgkin's Lymphoma in China [Phase 2]

A Phase 2 safety analysis evaluating intravenous rapid infusion of obinutuzumab in patients with B-cell non-Hodgkin's lymphoma conducted in …

CLINICAL_TRIALS trial_result · 2022-05-09

Clinical Trial Update: A Pharmacokinetic and Pharmacodynamic Study Comparing HLX01 And Rituximab in Patients With CD20-Positive, B-cell Lymphoma [Phase 1, Phase 2]

A pharmacokinetic and pharmacodynamic study comparing HLX01 and Rituximab in CD20-positive B-cell lymphoma completed Phase 1 and Phase 2.

CLINICAL_TRIALS trial_result · 2022-01-27

Clinical Trial Update: A Phase I/II Study of CM355 in Patients With Relapsed or Refractory B-Cell Non-Hodgkin's Lymphoma (B-NHL) [Phase 1, Phase 2]

Phase I/II study investigating CM355 in relapsed or refractory B-cell non-Hodgkin's lymphoma.

CLINICAL_TRIALS trial_result · 2021-12-21

Clinical Trial Update: Study of Zanubrutinib, Rituximab and Combination Chemotherapy in Newly-diagnosed Aggressive B-cell Non-Hodgkin Lymphoma [Phase 3]

Phase 3 clinical trial update investigating zanubrutinib with rituximab and/or combination chemotherapy for newly diagnosed aggressive B-cel…

CLINICAL_TRIALS trial_result · 2021-11-19

Clinical Trial Update: Orelabrutinib, Rituximab and Combination Chemotherapy in Newly-diagnosed Aggressive B-cell Non-Hodgkin Lymphoma [Phase 3]

Phase 3 trial update evaluating orelabrutinib with rituximab and combination chemotherapy for newly diagnosed aggressive B-cell non-Hodgkin …

CLINICAL_TRIALS trial_result · 2021-09-28

Clinical Trial Update: SHR1459 in Combination With YY-20394 in Recurrent and Refractory B-cell Non-Hodgkin's Lymphoma [Phase 2]

Phase 2 trial update for SHR1459 in combination with YY-20394 in recurrent and refractory B-cell non-Hodgkin's lymphoma is listed, with stat…

CLINICAL_TRIALS trial_result · 2021-06-24

Clinical Trial Update: CD8+ Memory T-Cells as Consolidative Therapy After Donor Non-myeloablative Hematopoietic Cell Transplant in Treating Patients With Leukemia or Lymphoma [Phase 2]

Phase 2 trial evaluating CD8+ memory T-cells as consolidative therapy after donor non-myeloablative hematopoietic cell transplant in leukemi…

CLINICAL_TRIALS trial_result · 2021-05-25

Clinical Trial Update: High-Dose Y-90-Ibritumomab Tiuxetan Added to Reduced-Intensity Allogeneic Stem Cell Transplant Regimen for Relapsed or Refractory Aggressive B-Cell Lymphoma [Phase 2]

Phase 2 trial evaluating high-dose Y-90 ibritumomab tiuxetan added to reduced-intensity allogeneic stem cell transplant for relapsed or refr…

CLINICAL_TRIALS trial_result · 2021-05-21

Clinical Trial Update: Azacytidine, Bendamustine, Piamprizumab in Refractory/Relapsed B-cell Non-Hodgkin's Lymphoma [Phase 1, Phase 2]

Phase 1/2 trial investigating azacytidine, bendamustine, and piamprizumab in refractory/relapsed B-cell non-Hodgkin lymphoma.

CLINICAL_TRIALS trial_result · 2021-03-03

Clinical Trial Update: Clinical Trial in Chinese Patients of B-cell Non-Hodgkin's Lymphoma(GB226) [Phase 2]

A Phase 2 clinical trial update for GB226 in Chinese patients with B-cell non-Hodgkin's lymphoma is reported; current status is unknown.

CLINICAL_TRIALS trial_result · 2021-01-13

Clinical Trial Update: Study to Evaluate Safety and Efficacy of Blinatumomab in Subjects With Relapsed/Refractory (R/R) Aggressive B-Cell NHL [Phase 2, Phase 3]

Phase 2/3 clinical trial update for blinatumomab in relapsed/refractory aggressive B-cell non-Hodgkin lymphoma completed with posted results…

CLINICAL_TRIALS trial_result · 2021-01-07

Clinical Trial Update: A Phase 2 Clinical Trial of Rituxan and B-Glucan PGG in Relapsed Indolent Non-Hodgkin Lymphoma [Phase 2]

Phase 2 trial evaluating Rituxan (rituximab) with beta-glucan PGG in relapsed indolent B-cell non-Hodgkin lymphoma has completed, with resul…

CLINICAL_TRIALS trial_result · 2020-11-27

Clinical Trial Update: Open-Label Extension Study of De-immunized DI-Leu16-IL2 Immunocytokine Administered in Participants With B-cell NHL [Phase 1, Phase 2]

Open-label extension study of de-immunized DI-Leu16-IL2 immunocytokine in participants with B-cell non-Hodgkin lymphoma; study terminated wi…

CLINICAL_TRIALS trial_result · 2020-11-24

Clinical Trial Update: A Study of De-immunized DI-Leu16-IL2 Administered Subcutaneously in Participants With B-cell NHL [Phase 1, Phase 2]

Phase 1/2 trial of de-immunized DI-Leu16-IL2 for B-cell non-Hodgkin lymphoma; study terminated with results posted.

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