B-cell Non-hodgkin Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-09Clinical Trial Update: Study Evaluating Brexucabtagene Autoleucel (KTE-X19) in Pediatric and Adolescent Participants With Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia or Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma [Phase 1, Phase 2]
This clinical trial update reports the completion of a phase 1/2 study evaluating Brexucabtagene autoleucel (KTE-X19) in pediatric and adole…
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CLINICAL_TRIALS trial_result · 2026-04-03Clinical Trial Update: AB-101 as Monotherapy and With Immunotherapy in Patients With Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma [Phase 1, Phase 2]
This clinical trial update reports on AB-101 as a monotherapy and in combination with immunotherapy for relapsed/refractory B-cell Non-Hodgk…
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CLINICAL_TRIALS trial_result · 2026-03-30Clinical Trial Update: Autologous CD22 CAR T Cells in Adults w/ Recurrent or Refractory B Cell Malignancies [Phase 1]
Phase 1 trial evaluating autologous CD22 CAR T cells in adults with recurrent or refractory B-cell malignancies has completed enrollment. Re…
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CLINICAL_TRIALS trial_result · 2026-03-16Clinical Trial Update: A Study Evaluating the Safety and Efficacy of GLPG5101 (19CP02) in Participants With Non-Hodgkin Lymphoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial update on the investigational drug GLPG5101 (19CP02) for Relapsed/Refractory B-cell Non-Hodgkin Lymphoma, with th…
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CLINICAL_TRIALS trial_result · 2026-03-11Clinical Trial Update: A Study to Evaluate the Safety and Preliminary Efficacy of ATA3219 in Participants With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma [Phase 1]
A Phase 1 trial update for ATA3219 in relapsed/refractory B-cell non-Hodgkin lymphoma notes that the study has been terminated, with safety …
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CLINICAL_TRIALS trial_result · 2026-03-05Clinical Trial Update: Genetically Modified T-cells (CMV-Specific CD19-CAR T-cells) Plus a Vaccine (CMV-MVA Triplex) for the Treatment of Intermediate or High Grade B-Cell Non-Hodgkin Lymphoma [Phase 1]
A Phase 1 clinical trial evaluating CMV-specific CD19-CAR T-cells in combination with the CMV-MVA Triplex vaccine for intermediate- or high-…
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CLINICAL_TRIALS trial_result · 2026-03-02Clinical Trial Update: A Study to Evaluate the Safety, Pharmacokinetics and Preliminary Anti-Tumor Activity of Englumafusp Alfa in Combination With Obinutuzumab and in Combination With Glofitamab Following a Pre-Treatment Dose of Obinutuzumab in Participants With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma [Phase 1, Phase 2]
Roche is conducting a Phase 1/2 trial to evaluate Englumafusp Alfa in combination with Obinutuzumab and in combination with Glofitamab after…
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CLINICAL_TRIALS trial_result · 2026-02-19Clinical Trial Update: Study of Valemetostat Tosylate as a Single Agent in Patients With Relapse/Refractory B-cell Lymphoma [Phase 2]
Valemetostat tosylate is being studied as a single-agent therapy for relapse or refractory B-cell lymphoma in a Phase 2 trial, which is curr…
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CLINICAL_TRIALS trial_result · 2026-02-09Clinical Trial Update: Intergroup Randomized Trial for Children or Adolescents With B-Cell Non Hodgkin Lymphoma or B-Acute Leukemia: Rituximab Evaluation in High Risk Patients [Phase 3]
A Phase 3 intergroup trial evaluating rituximab in high-risk pediatric patients with B-cell non-Hodgkin lymphoma or Burkitt leukemia has com…
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CLINICAL_TRIALS trial_result · 2026-01-30Clinical Trial Update: A Study of C-CAR039 in Subjects With Relapsed and/or Refractory B Cell Non-Hodgkin's Lymphoma [Phase 1]
This report covers the completion of a Phase 1 study evaluating the CAR-T therapy C-CAR039 in patients with relapsed or refractory B-cell no…
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CLINICAL_TRIALS trial_result · 2026-01-29Clinical Trial Update: Acalabrutinib + Liso-Cel In R/R Aggressive B-Cell Lymphomas [Phase 2]
Phase 2 study evaluating acalabrutinib plus lisocabtagene maraleucel (Liso-Cel) in refractory/relapsed aggressive B-cell lymphomas, includin…
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CLINICAL_TRIALS trial_result · 2026-01-13Clinical Trial Update: Trial of Anti-CD19 and Anti-CD20 Bicistronic Chimeric Antigen Receptor T Cells for Treating B-Cell Malignancies [Phase 1]
A Phase 1 clinical trial update for a bicistronic CAR-T cell therapy targeting CD19 and CD20 in B-cell malignancies; current status is not r…
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CLINICAL_TRIALS trial_result · 2025-12-24Clinical Trial Update: Preliminary Safety and Tolerability of CD19x22 CAR T Cells in Adolescent and Adult R/R B-NHL Patients [Phase 1]
Phase 1 study assessing safety and tolerability of CD19x22 CAR T cells in adolescents and adults with relapsed/refractory B-cell non-Hodgkin…
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CLINICAL_TRIALS trial_result · 2025-12-08Clinical Trial Update: STAY-STRONG Study of Exercise Training During Chemotherapy [NA]
The STAY-STRONG study evaluating exercise training during chemotherapy in lymphoma patients has completed, examining effects on body composi…
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CLINICAL_TRIALS trial_result · 2025-12-01Clinical Trial Update: Targeting CD19/CD20 Dual-targeted Cell in Patients With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma [Phase 1]
Phase 1 study of a CD19/CD20 dual-targeted cell therapy in relapsed or refractory B-cell non-Hodgkin lymphoma has been terminated.
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CLINICAL_TRIALS trial_result · 2025-10-23Clinical Trial Update: Anakinra for the Prevention of Cytokine Release Syndrome and Neurotoxicity in Patients With B-Cell Non-Hodgkin Lymphoma Receiving CD19-Targeted CAR-T Cell Therapy [Phase 2]
A Phase 2 trial evaluating anakinra to prevent cytokine release syndrome and neurotoxicity in patients with B-cell non-Hodgkin lymphoma rece…
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CLINICAL_TRIALS trial_result · 2025-10-15Clinical Trial Update: Study of Acalabrutinib Alone or in Combination Therapy in Subjects With B-cell Non-Hodgkin Lymphoma [Phase 1, Phase 2]
Acalabrutinib is being studied in Phase 1/2 as a single agent or in combination therapy for B-cell non-Hodgkin lymphoma, with results posted…
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CLINICAL_TRIALS trial_result · 2025-10-15Clinical Trial Update: A Study to Assess the Anti-Tumor Activity and Safety of Odronextamab in Adult Patients With B-cell Non-Hodgkin Lymphoma Who Have Been Previously Treated With Other Cancer Therapies [Phase 2]
Phase 2 clinical trial update evaluating the anti-tumor activity and safety of odronextamab in adults with B-cell non-Hodgkin lymphoma who h…
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CLINICAL_TRIALS trial_result · 2025-10-08Clinical Trial Update: Acalabrutinib and Anti-CD19 CAR T-cell Therapy for the Treatment of B-cell Lymphoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating the combination of acalabrutinib with anti-CD19 CAR T-cell therapy for various B-cell lymphomas, in…
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CLINICAL_TRIALS trial_result · 2025-10-01Clinical Trial Update: IKS03 in Patients With Advanced B Cell Non-Hodgkin Lymphomas [Phase 1]
Phase 1 study update for IKS03 in advanced B-cell non-Hodgkin lymphomas is currently recruiting across multiple subtypes including diffuse l…
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CLINICAL_TRIALS trial_result · 2025-09-30Clinical Trial Update: Modified Immune Cells (AFM13-NK) and A Monoclonal Antibody (AFM13) in Treating Patients With Recurrent or Refractory CD30 Positive Hodgkin or Non-Hodgkin Lymphomas [Phase 1, Phase 2]
This is a completed Phase 1/2 clinical trial from MD Anderson evaluating AFM13 and AFM13-NK in patients with recurrent or refractory CD30-po…
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CLINICAL_TRIALS trial_result · 2025-08-26Clinical Trial Update: Rituximab and Combination Chemotherapy With or Without Radiation Therapy in Treating Patients With B-Cell Non-Hodgkin's Lymphoma [Phase 3]
Phase 3 trial evaluating Rituximab plus chemotherapy, with or without radiation therapy, in patients with B-cell non-Hodgkin lymphoma; trial…
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CLINICAL_TRIALS trial_result · 2025-08-26Clinical Trial Update: CD19 CAR T-Cell Therapy for R/R Non-Hodgkin Lymphoma and Acute Lymphoblastic Leukemia [Phase 1]
Phase 1 trial of CD19 CAR T-cell therapy for relapsed/refractory B-cell non-Hodgkin lymphoma and B-cell acute lymphoblastic leukemia has com…
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CLINICAL_TRIALS trial_result · 2025-08-20Clinical Trial Update: Tailored Prednisone Reduction in Preventing Hyperglycemia in Participants With B-Cell Non-Hodgkin Lymphoma Receiving Combination Chemotherapy Treatment [Phase 2]
Phase 2 trial update evaluating tailored prednisone reduction to prevent hyperglycemia in patients with B-cell non-Hodgkin lymphoma undergoi…
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CLINICAL_TRIALS trial_result · 2025-07-18Clinical Trial Update: The Safety, Tolerability, and Efficacy of IBR900 Cell Injection in Relapsed/Refractory B-cell Non Hodgkin Lymphoma [Phase 1]
Phase 1 trial update evaluating the safety, tolerability, and potential efficacy of IBR900 cell injections in patients with relapsed or refr…