B-cell Lymphoma
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CLINICAL_TRIALS trial_result · 2016-12-14Clinical Trial Update: Anti-CD19:TCRζ Chimeric Antigen Receptor-T Cells in the Treatment for CD19+ B Cell Lymphoma [Phase 4]
This document reports a Phase 4 clinical trial of anti-CD19:TCRζ CAR-T cells for CD19-positive B-cell lymphoma. The current status is UNKNOW…
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CLINICAL_TRIALS trial_result · 2016-10-14Clinical Trial Update: CD19-redirected Autologous Cells (CAR-CD19 T Cells) [Phase 1]
Phase 1 clinical trial update on autologous CAR-CD19 T cells targeting CD19-positive malignant B-cell leukemia and lymphoma.
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CLINICAL_TRIALS trial_result · 2016-10-13Clinical Trial Update: A Study of Brentuximab Vedotin in Relapsed or Refractory Non-Hodgkin Lymphoma [Phase 2]
A Phase 2 trial of Brentuximab Vedotin in relapsed or refractory non-Hodgkin lymphoma has completed and results have been posted. The study …
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CLINICAL_TRIALS trial_result · 2016-08-17Clinical Trial Update: Safety and Efficacy of Bexxar Therapy in the Treatment of Relapsed/Residual B-Cell Lymphoma After Autologous Transplant [Phase 1]
This Phase 1 trial update reports on the safety and preliminary efficacy of Bexxar (tositumomab) in patients with relapsed or residual B-cel…
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CLINICAL_TRIALS trial_result · 2016-06-28Clinical Trial Update: Study of an Investigational Drug, ASP3026, in Patients With Advanced Malignancies (Solid Tumors and B-Cell Lymphoma) [Phase 1]
A Phase 1 clinical trial of ASP3026 in patients with advanced malignancies, including solid tumors and B-cell lymphoma, has completed.
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CLINICAL_TRIALS trial_result · 2016-06-24Clinical Trial Update: Safety and Efficacy Study of a Dual PI3K Delta/Gamma Inhibitor in Hematological Malignancies [Phase 1]
Phase 1 study of a dual PI3K Delta/Gamma inhibitor in B-cell and T-cell lymphomas has completed, assessing safety and preliminary efficacy.
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CLINICAL_TRIALS trial_result · 2016-02-19Clinical Trial Update: High Dose, Absorbed Dose Adjusted 90Y-ibritumomab With Peripheral Blood Stem Cells (PBSC) Support in B-cell Lymphoma [Phase 1, Phase 2]
This clinical trial update reports the completion of Phase 1/2 testing of high-dose, absorbed-dose-adjusted 90Y-ibritumomab tiuxetan with pe…
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CLINICAL_TRIALS trial_result · 2015-07-07Clinical Trial Update: Multi-level Evaluation of Chemotherapy-induced Febrile Neutropenia Prophylaxis, Outcomes, and Determinants With Granulocyte-colony Stimulating Factor
A completed clinical trial evaluated granulocyte-colony stimulating factor (G-CSF) for prevention of chemotherapy-induced febrile neutropeni…
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CLINICAL_TRIALS trial_result · 2015-01-29Clinical Trial Update: Dose Escalation Study of Clofarabine in Patients With Relapsed or Refractory Low Grade or Intermediate-Grade B-Cell Lymphoma [Phase 1]
This Phase 1 dose-escalation trial evaluated clofarabine in patients with relapsed or refractory low-grade or intermediate-grade B-cell lymp…
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CLINICAL_TRIALS trial_result · 2014-12-30Clinical Trial Update: Study for Evaluation of Efficacy and Safety of SH L 749 to Indolent B-cell Non-Hodgkin's Lymphoma [Phase 2]
This document reports the completion of a Phase 2 clinical trial evaluating the efficacy and safety of SH-L-749 in indolent B-cell non-Hodgk…
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CLINICAL_TRIALS trial_result · 2014-12-02Clinical Trial Update: A Phase I Study of the Chimeric Anti-CD40 Monoclonal Antibody ChiLob 7/4 to Treat Advanced Malignancies Refractory to Conventional Anti-cancer Treatment [Phase 1]
Phase I study of ChiLob 7/4, a chimeric anti-CD40 monoclonal antibody, in patients with advanced cancers refractory to conventional treatmen…
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CLINICAL_TRIALS trial_result · 2014-06-19Clinical Trial Update: AZD6738 First Time in Patient Multiple Ascending Dose Study [Phase 1]
AZD6738 (berzosertib) was studied in a first-in-patient, multiple ascending-dose Phase 1 trial in relapsed/refractory hematologic cancers in…
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CLINICAL_TRIALS trial_result · 2013-09-27Clinical Trial Update: VELCADE,Rituximab,Cyclophosphamide and Decadron [Phase 2]
Phase 2 trial update for Velcade in combination with Rituximab, Cyclophosphamide, and Decadron in B-cell non-Hodgkin lymphoma, with terminat…
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CLINICAL_TRIALS trial_result · 2013-05-22Clinical Trial Update: Study of the Safety and Tolerability of PCI-32765 in Patients With Recurrent B Cell Lymphoma [Phase 1]
Phase 1 study assessing the safety and tolerability of PCI-32765 (ibrutinib) in patients with recurrent B-cell lymphoma or B-cell leukemia; …
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CLINICAL_TRIALS trial_result · 2013-03-15Clinical Trial Update: Study of Canfosfamide in Refractory or Relapsed Mantle Cell, Diffuse Large B Cell Lymphoma and Multiple Myeloma [Phase 2]
This update reports the completion of a Phase 2 study of canfosfamide in refractory or relapsed mantle cell lymphoma, B-cell lymphoma, and m…
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CLINICAL_TRIALS trial_result · 2012-09-26Clinical Trial Update: Study of Standard-Dose Rituximab, Ifosfamide, Carboplatin and Etoposide [Phase 1]
Phase 1 trial evaluating Rituximab with Ifosfamide, Carboplatin, and Etoposide for Non-Hodgkin lymphoma has been terminated.
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CLINICAL_TRIALS trial_result · 2012-09-18Clinical Trial Update: Study of Pralatrexate & Gemcitabine With B12 & Folic Acid to Treat Relapsed/Refractory Lymphoproliferative Malignancies [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating pralatrexate and gemcitabine with B12 and folic acid in relapsed/refractory lymphoproliferative malignan…
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CLINICAL_TRIALS trial_result · 2012-09-11Clinical Trial Update: PS-341 Alone and PS-341 Plus EPOCH Chemotherapy to Treat Non-Hodgkin's Lymphoma [Phase 2]
Phase 2 trial evaluating PS-341 (bortezomib) alone and with EPOCH chemotherapy for Non-Hodgkin lymphoma; results were posted in 2012.
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CLINICAL_TRIALS trial_result · 2012-03-28Clinical Trial Update: Treatment of Mature B-cell Lymphoma/Leukaemia [Phase 3]
Phase 3 clinical trial evaluating treatment for mature B-cell lymphoma has completed. Sponsored by Gustave Roussy/Cancer Campus Grand Paris,…
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CLINICAL_TRIALS trial_result · 2011-10-12Clinical Trial Update: A Safety/Efficacy Study of SGN-30 (Antibody) in Patients With Refractory or Recurrent CD30+ Hematologic Malignancies [Phase 1, Phase 2]
This completed Phase 1/2 trial evaluated the safety and preliminary efficacy of SGN-30 (brentuximab vedotin) in patients with CD30-positive …
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CLINICAL_TRIALS trial_result · 2011-07-20Clinical Trial Update: Intratumoral Poly-ICLC Plus Low Dose Local Radiation in Low Grade Recurrent B and T Cell Lymphoma [Phase 1]
Phase 1 trial assessing intratumoral Poly-ICLC with low-dose local radiation in low-grade recurrent B-cell and T-cell lymphomas; the study w…
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CLINICAL_TRIALS trial_result · 2008-10-27Clinical Trial Update: Study of L-NDDP (Aroplatin) in Patients With Advanced Solid Malignancies or B-Cell Lymphoma [Phase 1]
Phase 1 study of L-NDDP (Aroplatin) in patients with advanced solid malignancies or B-cell lymphoma has completed.
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CLINICAL_TRIALS trial_result · 2006-09-08Clinical Trial Update: Yttrium-90 Ibritumomab Tiuxetan (Zevalin) With BEAM in Relapsed Low Grade B-Cell Lymphoma [Phase 2]
A Phase 2 trial evaluating Yttrium-90 ibritumomab tiuxetan (Zevalin) with BEAM conditioning in relapsed low-grade B-cell lymphoma has been c…