B-cell Lymphoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: Study of the Clearance of Minimal Residual Disease Measured at the End of First-line Treatment in Patients With Lymphoma [NA]
This clinical trial update describes a study evaluating clearance of minimal residual disease at the end of first-line treatment in patients…
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: Bispecific CAR T Cells for B-cell Malignancies (BaseCAR-01 Trial) [Phase 1]
This Clinical Trial Update describes BaseCAR-01, a Phase 1 study evaluating bispecific CAR T cells in B-cell malignancies, with recruitment …
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Anti-CD19 CAR-T Cells With Inducible Caspase 9 Safety Switch for B-cell Lymphoma [Phase 1]
Phase 1 clinical trial update of anti-CD19 CAR-T cells with an inducible caspase-9 safety switch for B-cell lymphoma, currently active but n…
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CLINICAL_TRIALS research · 2025-12-01Clinical Trial Update: Gene Therapy Follow-up Protocol for People Previously Enrolled in CAR-T Cell Studies
Clinical trial update describing a follow-up protocol for individuals previously enrolled in CAR-T cell studies, detailing a gene therapy fo…
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: Universal CAR-T Cell Therapy for NHL [NA]
Recruitment is ongoing for a universal CAR-T cell therapy being studied in non-Hodgkin lymphoma (B-cell subtype), sponsored by Bioray Labora…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: A Phase 1 Study of JV-213 Autologous CD79b-targeting Chimeric Antigen Receptor T-cell Therapy in Adults With Relapsed or Refractory B-cell Lymphomas [Phase 1]
A Phase 1 study evaluating JV-213, an autologous CD79b-targeting CAR T-cell therapy, in adults with relapsed or refractory B-cell lymphomas;…
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CLINICAL_TRIALS research · 2025-10-21Clinical Trial Update: Kappa-CD28 T Lymphocytes, Chronic Lymphocytic Leukemia, B-cell Lymphoma or Multiple Myeloma, CHARKALL [Phase 1]
Phase 1 clinical trial update for Kappa-CD28 T lymphocytes in chronic lymphocytic leukemia, B-cell lymphoma, and multiple myeloma. The study…
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CLINICAL_TRIALS research · 2025-10-14Clinical Trial Update: Family Study of Lymphoproliferative Disorders
A Mayo Clinic-led clinical trial is a family study investigating lymphoproliferative disorders, currently in the recruitment phase.
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CLINICAL_TRIALS research · 2025-09-25Clinical Trial Update: Clinical Trial Using CAR- T Cells for Treatment of Patients With Refractory or Relapsed CD19-positive B Lymphoid Malignancies [Phase 1]
A Phase 1 clinical trial update for CD19-directed CAR-T cell therapy in patients with refractory or relapsed B lymphoid malignancies is curr…
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: A Study of LP-168 in Participants With Relapse or Refractory B-Cell Lymphoma [Phase 1]
This document describes a Phase 1 clinical trial evaluating LP-168 in participants with relapse or refractory B-cell lymphoma. The study is …
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: Phase 1 Trial of BTM-3566 in Relapsed/Refractory Mature B Cell Lymphomas [Phase 1]
Phase 1 trial evaluating BTM-3566 in relapsed/refractory mature B-cell lymphomas is currently recruiting.
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CLINICAL_TRIALS research · 2025-09-09Clinical Trial Update: This is a Phase I/II Interventional, Open-label Treatment Study Designed to Evaluate the Safety and Efficacy of Anti CD 19/22 CAR- T Cells Immunotherapy for Adults With Relapsed or Refractory Acute Lymphoblastic Leukemia/Lymphoma. [Phase 1, Phase 2]
This Phase I/II open-label trial evaluates an anti-CD19/CD22 CAR-T cell therapy in adults with relapsed or refractory acute lymphoblastic le…
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CLINICAL_TRIALS research · 2025-09-02Clinical Trial Update: Early Assessment of Cardiac Function After Treatment With CAR-T Cells
A clinical trial update reporting early cardiac function assessment in patients treated with CAR-T cell therapy for hematologic malignancies…
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CLINICAL_TRIALS research · 2025-08-15Clinical Trial Update: A Feasibility Trial of Tazemetostat Plus CAR T Cell Therapy in B-cell Lymphomas [Phase 1]
Phase 1 feasibility trial evaluating the combination of tazemetostat with CAR T-cell therapy in B-cell lymphomas, including follicular lymph…
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: Efficacy and Safety of CD19CD20-CAR.p40-T in B-cell Lymphoma [Phase 1, Phase 2]
A phase 1/2 clinical trial is evaluating the efficacy and safety of CD19CD20-CAR.p40-T in relapsed/refractory B-cell lymphoma and is current…
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CLINICAL_TRIALS research · 2025-07-30Clinical Trial Update: Novel Allogenic CD19-targeting CAR-γδT Cell Therapy (QH103E) in r/r NHL [Phase 1, Phase 2]
A Phase 1/2 study of an allogeneic CD19-targeting CAR-γδT cell therapy (QH103E) for relapsed/refractory non-Hodgkin lymphoma is currently re…
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CLINICAL_TRIALS research · 2025-07-30Clinical Trial Update: Clinical Study of Multi-targeted CAR-T Therapy in Patients With Relapsed/Refractory B-Cell Lymphoma [Phase 1]
This entry provides an update on an ongoing Phase 1 clinical study of a multi-targeted CAR-T therapy for relapsed/refractory B-cell lymphoma…
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CLINICAL_TRIALS research · 2025-07-28Clinical Trial Update: A Phase I/II Trial of ALETA-001 for the Treatment of Participants With B-cell Malignancies [Phase 1, Phase 2]
This document outlines a Phase I/II clinical trial of ALETA-001 for various B-cell lymphomas, with recruitment ongoing and sponsored by Canc…
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CLINICAL_TRIALS research · 2025-07-10Clinical Trial Update: A Clinical Study of Allogeneic CD19/BCMA CAR-T Cells for the Treatment of R/R B-cell Malignant Tumors [EARLY_Phase 1]
This is an early-phase study evaluating allogeneic CD19/BCMA CAR-T cells for relapsed/refractory B-cell malignancies, currently recruiting.
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CLINICAL_TRIALS research · 2025-07-02Clinical Trial Update: CD30 CAR-T in the Treatment of CD30 Positive Lymphoma [EARLY_Phase 1]
An early-phase 1 clinical trial evaluating a CD30-targeted CAR-T therapy for CD30-positive lymphomas is listed as not yet recruiting, sponso…
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CLINICAL_TRIALS research · 2025-07-02Clinical Trial Update: Study of TBI-2001(Autologous CD19 Specific Chimeric Antigen Receptor (CAR) Gene-transduced T Lymphocytes) for Relapsed or Refractory CD19+ B-cell Lymphoma, CLL/SLL [Phase 1]
Phase 1 clinical trial evaluating autologous CD19-specific CAR T cells (TBI-2001) for relapsed or refractory CD19+ B-cell lymphoma, chronic …
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CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: BCOR and ZC3H12 Genes Knock-out CD19-targeting CAR-T Cell Therapy in r/r B Cell Lymphoma [Phase 1, Phase 2]
A phase 1/2 clinical trial is evaluating a CD19-targeting CAR-T cell therapy with BCOR and ZC3H12 gene knock-outs for relapsed/refractory B-…
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CLINICAL_TRIALS research · 2025-06-08Clinical Trial Update: Pembrolizumab in Combination With Chemotherapy for Patients With Untreated B Cell Lymphoma [Phase 2]
This clinical trial update describes a Phase 2 study at the University of Chicago assessing pembrolizumab plus chemotherapy for untreated B-…
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CLINICAL_TRIALS research · 2025-06-05Clinical Trial Update: Efficacy and Safety Evaluation of U01(ssCART-19) in B-Cell Lymphoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating U01(ssCART-19) for B-cell lymphoma is ongoing. The study is currently recruiting at Shanghai Tongji Ho…
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CLINICAL_TRIALS research · 2025-03-10Clinical Trial Update: CD-19 CAR-T Cell for Pediatric ALL or Lymphoma [NA]
Clinical trial update for a CD-19 CAR-T cell therapy being investigated for pediatric acute lymphoblastic leukemia and pediatric lymphoma; t…