Atrial Fibrillation
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CLINICAL_TRIALS trial_result · 2025-11-19Clinical Trial Update: A Pilot Study on the Prevention of the Vascular RISK Related to Atrial Fibrillation After Intracranial Hemorrhage by Closing the Left Auricle [NA]
A pilot study evaluating left atrial appendage closure to reduce vascular risk in patients with atrial fibrillation after intracranial hemor…
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CLINICAL_TRIALS research · 2025-11-19Clinical Trial Update: BEACON-AA: Apixaban With or Without Clopidogrel in Stroke Patients With Atrial Fibrillation and Cerebral Atherosclerosis [Phase 4]
This document updates the status of BEACON-AA, a Phase 4 trial evaluating apixaban with or without clopidogrel in stroke patients with atria…
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CLINICAL_TRIALS trial_result · 2025-11-19Clinical Trial Update: Abbott Atrial Fibrillation Post Approval Study
Abbott's post-approval atrial fibrillation study is active but not recruiting, indicating ongoing post-market surveillance of the device.
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CLINICAL_TRIALS trial_result · 2025-11-19Clinical Trial Update: Pulmonary Vein Isolation vs SHAM-pulmonary Vein Isolation for Symptomatic Relief in Patients With AF [NA]
A clinical trial comparing pulmonary vein isolation to a sham procedure for symptomatic relief in patients with atrial fibrillation is curre…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Substrate Remodelling and Targeted Ablation in AF [NA]
The study, sponsored by Barts & The London NHS Trust, is testing substrate remodeling and targeted ablation strategies for atrial fibrillati…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Renal Denervation in Patients With Recurrent Atrial Fibrillation After Successful Pulmonary Vein Isolation [NA]
A clinical trial evaluating renal denervation to reduce arrhythmia burden in patients with recurrent paroxysmal atrial fibrillation after du…
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CLINICAL_TRIALS research · 2025-11-14Clinical Trial Update: Semaglutide for Metabolic Intervention and Adipose Loss to Treat Atrial Fibrillation [Phase 3]
Phase 3 clinical trial is currently recruiting to assess semaglutide as a metabolic intervention and adipose loss strategy for treating atri…
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CLINICAL_TRIALS research · 2025-11-14Clinical Trial Update: Machine Learning in Atrial Fibrillation
Stanford University is conducting a clinical trial using machine learning in atrial fibrillation that is currently recruiting.
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CLINICAL_TRIALS research · 2025-11-14Clinical Trial Update: COMparison of Physiological Algorithms for Real-time Evaluation of Atrial Fibrillation
Stanford University sponsors a clinical study comparing physiological algorithms for real-time evaluation of atrial fibrillation, and the tr…
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FDA approval · 2025-11-14FDA Approved: DILTIAZEM HYDROCHLORIDE — Original Application (Alembic Pharmaceuticals Limited)
FDA approves the original application for diltiazem hydrochloride (Alembic Pharmaceuticals Limited), a generic product, for use in treating …
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CLINICAL_TRIALS trial_result · 2025-11-12Clinical Trial Update: Rural Hospital-Level Care at Home for Acutely Ill Adults [NA]
This clinical trials.gov entry notes that the Brigham and Women's Hospital study on rural hospital-level care at home for acutely ill adults…
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CLINICAL_TRIALS trial_result · 2025-11-10Clinical Trial Update: Diltiazem in the Treatment of Atrial Fibrillation or Atrial Flutter With Rapid Ventricular Rate [Phase 4]
Phase 4 clinical trial update evaluating diltiazem for atrial fibrillation or atrial flutter with rapid ventricular rate; results have been …
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CLINICAL_TRIALS trial_result · 2025-11-06Clinical Trial Update: Atrial Fibrillation, Cardiac Symptoms, and Anxiety [NA]
This is a completed clinical trial (NCT02133365) sponsored by Brigham and Women's Hospital investigating atrial fibrillation, cardiac sympto…
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CLINICAL_TRIALS trial_result · 2025-11-05Clinical Trial Update: Comparison of Pulmonary Vein Ablation With or Without Left Atrial Posterior Wall Ablation for Persistent AF (PIVoTAL) [NA]
A completed trial comparing pulmonary vein ablation with versus without left atrial posterior wall ablation for persistent atrial fibrillati…
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EMA approval · 2025-11-05EMA Authorised: Rivaroxaban Viatris (previously Rivaroxaban Mylan) (rivaroxaban) — Viatris Limited
The EMA authorised Viatris Limited to market rivaroxaban (brand name Rivaroxaban Viatris), expanding access to this anticoagulant as a gener…
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CLINICAL_TRIALS withdrawal · 2025-11-04Clinical Trial Update: Can the Lambre Device Occlude IRRegular And Large Appendages in Patients With Non-Valvular AF [NA]
A clinical trial investigating the Lambre Device for occluding the left atrial appendage in non-valvular atrial fibrillation patients has be…
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CLINICAL_TRIALS research · 2025-10-31Clinical Trial Update: REView of ProcEdural FactoRs and Outcomes After Atrial Fibrillation Ablation With Active Esophageal COOLing: A Sub-Study of the REAL AF Registry
This document provides an update on a sub-study within the REAL AF Registry evaluating outcomes after atrial fibrillation ablation with acti…
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CLINICAL_TRIALS research · 2025-10-31Clinical Trial Update: A Registry Based Collaborative to Measure Efficiency, Effectiveness, and Safety of Farapulse PFA Technology for AF
A registry-based collaboration to assess the efficiency, effectiveness, and safety of Farapulse pulsed-field ablation technology for atrial …
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CLINICAL_TRIALS research · 2025-10-30Clinical Trial Update: Safety and Efficacy of Workflows of High Volume Single Operators in a LAAO Device Implant Procedural Day
A clinical trial assessing safety and efficacy workflows for high-volume single operators performing left atrial appendage occluder (LAAO) d…
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EMA approval · 2025-10-28EMA Authorised: Multaq (dronedarone) — Sanofi Winthrop Industrie
EMA authorised Multaq (dronedarone) for the treatment of atrial fibrillation under the Sanofi Winthrop Industrie marketing authorization. Th…
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CLINICAL_TRIALS research · 2025-10-28Clinical Trial Update: CLIP-IT Post-Market Study [NA]
Post-market study update for Medtronic Cardiac Surgery's CLIP-IT device assessing left atrial appendage exclusion; the study is currently ac…
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CLINICAL_TRIALS research · 2025-10-28Clinical Trial Update: Esophageal Temperature During PVI Using Q-DOT Micro [NA]
A clinical trial is currently recruiting to evaluate esophageal temperature monitoring during pulmonary vein isolation using the Q-DOT Micro…
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CLINICAL_TRIALS research · 2025-10-28Clinical Trial Update: Comparing Magnesium 2g Versus 4g Versus Placebo in the Incidence of Treating AFF RVR [Phase 3]
Phase 3 trial comparing 2 g and 4 g magnesium sulfate versus placebo for atrial fibrillation with rapid ventricular response is currently re…
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CLINICAL_TRIALS trial_result · 2025-10-24Clinical Trial Update: A Prospective Single Arm Open Label Study of the FARAPULSE Pulsed Field Ablation System in Subjects With Persistent Atrial Fibrillation [NA]
The trial is a prospective single-arm, open-label study evaluating the FARAPULSE Pulsed Field Ablation System in patients with persistent at…
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CLINICAL_TRIALS trial_result · 2025-10-23Clinical Trial Update: DiamondTemp™ System for the Treatment of Persistent Atrial Fibrillation [NA]
The DiamondTemp System by Medtronic completed a trial for persistent atrial fibrillation, with results posted on 2025-10-23.