Atherosclerosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-04-03Clinical Trial Update: Safety and Efficacy Study of Ad2/Hypoxia Inducible Factor (HIF)-1α/VP16 Gene Transfer in Patients With Intermittent Claudication [Phase 2]
Phase 2 trial of Ad2/HIF-1α/VP16 gene transfer for intermittent claudication (peripheral artery disease) completed, reporting safety and eff…
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CLINICAL_TRIALS trial_result · 2015-04-03Clinical Trial Update: Effect of Aged Garlic Extract on Atherosclerosis [Phase 4]
Phase 4 clinical trial completed and results posted evaluating aged garlic extract for its effect on atherosclerosis in people with metaboli…
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CLINICAL_TRIALS trial_result · 2015-03-31Clinical Trial Update: Relation of Circulating Endothelium-derived Microparticle to Carotid Atherosclerosis
The completed trial investigates the relationship between circulating endothelial-derived microparticles and carotid atherosclerosis. It exp…
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CLINICAL_TRIALS trial_result · 2015-03-20Clinical Trial Update: ION US Post-Approval Study
US post-approval study results for the ION coronary device were completed and results were posted in 2015.
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CLINICAL_TRIALS withdrawal · 2015-03-18Clinical Trial Update: Effects on Atherosclerosis Regression of Ezetimibe or Ezetimibe Plus Simvastatin; Evaluated by Fluorodeoxyglucose Positron Emission Tomography (FDG-PET) [NA]
The clinical trial evaluating ezetimibe alone or in combination with simvastatin for atherosclerosis regression, assessed by FDG-PET, has be…
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CLINICAL_TRIALS trial_result · 2015-03-13Clinical Trial Update: DOCTOR Compare - A Study in the "DOCTOR" Series (Does Optical Coherence Tomography Optimize Revascularization?"
Completion of the DOCTOR Compare study, a trial evaluating whether Optical Coherence Tomography-guided revascularization improves management…
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CLINICAL_TRIALS trial_result · 2015-03-06Clinical Trial Update: Safety & Effectiveness on Vascular Structure and Function of ACZ885 in Atherosclerosis and Either T2DM or IGT Patients [Phase 2]
A Phase 2 trial evaluating ACZ885 (canakinumab) for safety and vascular outcomes in patients with atherosclerosis and either type 2 diabetes…
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CLINICAL_TRIALS trial_result · 2015-02-27Clinical Trial Update: Evaluation of The Effects of Nebivolol in Comparison to Atenolol on Wall Shear Stress and Rupture Prone Coronary Plaques [Phase 4]
Phase 4 trial comparing nebivolol to atenolol assesses effects on wall shear stress and rupture-prone coronary plaques in atherosclerosis.
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CLINICAL_TRIALS trial_result · 2015-02-26Clinical Trial Update: Statin Therapy to Improve Atherosclerosis in HIV Patients [NA]
A completed Massachusetts General Hospital clinical trial assessed statin therapy to improve atherosclerosis in HIV-infected patients; resul…
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CLINICAL_TRIALS trial_result · 2015-02-25Clinical Trial Update: Imaging and Biomarkers of Atherosclerosis in Patients With Stable or Unstable Coronary Artery Disease [NA]
This completed clinical trial from Assistance Publique - Hôpitaux de Paris investigates imaging and biomarkers of atherosclerosis in patient…
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CLINICAL_TRIALS trial_result · 2015-02-20Clinical Trial Update: A Web-based Approach to Treating Cardiovascular Disease Risk in Employees With Metabolic Syndrome [NA]
A completed clinical trial evaluated a web-based approach to reducing cardiovascular disease risk among employees with metabolic syndrome.
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CLINICAL_TRIALS trial_result · 2015-02-09Clinical Trial Update: BIOLUX P-II First-in-Man Study to Compare the Passeo-18 Lux DRB Against POBA in Infrapopliteal Arteries [NA]
A completed first-in-man trial evaluating Biotronik's paclitaxel-coated Passeo-18 Lux DRB balloon versus plain balloon angioplasty in infrap…
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CLINICAL_TRIALS trial_result · 2015-02-09Clinical Trial Update: BIOLUX P-I First in Man Study [NA]
Biotronik AG reports completion of the BIOLUX P-I first-in-man clinical trial evaluating a vascular device for arterial disease.
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CLINICAL_TRIALS trial_result · 2015-02-05Clinical Trial Update: Impact of Dabigatran and Phenprocoumon on Clopidogrel Mediated ADP Induced Platelet Aggregation in Patients With Atrial Fibrillation [Phase 4]
Phase 4 trial update examining how dabigatran and phenprocoumon influence clopidogrel-mediated platelet aggregation in patients with atrial …
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CLINICAL_TRIALS trial_result · 2015-01-27Clinical Trial Update: BioImage Study: A Clinical Study of Burden of Atherosclerotic Disease in an At-Risk Population
The BioImage Study, a clinical trial assessing the burden of atherosclerotic disease in at-risk individuals, has completed.
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CLINICAL_TRIALS research · 2015-01-27Clinical Trial Update: Prospective Identification of High-risk Coronary Plaques Through Non-invasive Imaging
This clinical trial update describes a study aiming to prospectively identify high-risk coronary plaques using non-invasive imaging; current…
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CLINICAL_TRIALS trial_result · 2015-01-16Clinical Trial Update: The Long-term Results of the No-touch Vein Graft to the Left Anterior Descending Artery.
This update reports the long-term results from a completed clinical trial evaluating the no-touch vein graft technique to the left anterior …
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CLINICAL_TRIALS research · 2015-01-06Clinical Trial Update: Effect of BAriatric Surgery Versus Optimal Medical Therapy on Cardiovascular Health and Atherosclerosis in Obese, Type II Diabetic Patients [NA]
A clinical trial update examining the impact of bariatric surgery versus optimal medical therapy on cardiovascular health and atherosclerosi…
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CLINICAL_TRIALS trial_result · 2014-12-19Clinical Trial Update: Antiretrovirals and Rate of Progression in Carotid Artery Intima-medial Thickness in HIV
A completed clinical trial assessing whether antiretroviral therapy affects the progression of carotid artery intima-media thickness in peop…
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CLINICAL_TRIALS trial_result · 2014-12-11Clinical Trial Update: Human Lipoprotein Pathophysiology - Subproject: Genetics of Familial Combined Hyperlipidemia
This clinical trial update reports the completion of a subproject on the genetics of familial combined hyperlipidemia, sponsored by the Univ…
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CLINICAL_TRIALS research · 2014-12-03Clinical Trial Update: Serum Sex Hormone Levels and Subclinical Atherosclerosis - Ancillary to MESA
This entry reports a completed ancillary clinical trial to the MESA study examining how serum sex hormone levels relate to subclinical ather…
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CLINICAL_TRIALS trial_result · 2014-12-03Clinical Trial Update: Pulmonary Disease in Patients Referred for Coronary CT
This entry reports the completion of a clinical trial studying pulmonary disease in patients referred for coronary CT, sponsored by Universi…
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CLINICAL_TRIALS trial_result · 2014-11-21Clinical Trial Update: A Prospective, Multi-center, Single Arm Study Evaluating the Express™ Renal Premounted Stent System in the Treatment of Atherosclerotic Lesions in the Aortorenal Ostium. [Phase 4]
This Phase 4, multicenter, single-arm trial evaluated the Express Renal Premounted Stent System for atherosclerotic lesions at the aortorena…
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CLINICAL_TRIALS trial_result · 2014-11-17Clinical Trial Update: Molecular and Clinical Effects of Green Tea and Fermented Papaya Preparation on Diabetes and Cardiovascular Diseases [Phase 2, Phase 3]
Phase 2/3 clinical trial evaluating the effects of green tea and fermented papaya preparation on diabetes and cardiovascular risk markers ha…
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CLINICAL_TRIALS trial_result · 2014-10-30Clinical Trial Update: Percentage of Secondary Prevention Patients Treated to Their LDL-C Targets
This clinical trial update reports the proportion of secondary prevention patients who achieved their LDL-C targets.