Atherosclerosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-04-27Clinical Trial Update: Trial of Clopidogrel After Surgery for Coronary Artery Disease (CASCADE Trial) [Phase 2]
Phase 2 trial update on clopidogrel after surgery for coronary artery disease (CASCADE Trial) completed with results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-04-20Clinical Trial Update: Impact of PCSK9 Inhibitors on Coronary Plaque Composition and Vulnerability Assessed by Optical Coherence Tomography [Phase 4]
Phase 4 trial update evaluating the impact of PCSK9 inhibitors on coronary plaque composition and vulnerability using optical coherence tomo…
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CLINICAL_TRIALS trial_result · 2021-03-09Clinical Trial Update: Safety of PZ-128 in Subjects Undergoing Non-Emergent Percutaneous Coronary Intervention [Phase 2]
Phase 2 safety data for PZ-128 in subjects undergoing non-emergent percutaneous coronary intervention have been posted.
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CLINICAL_TRIALS trial_result · 2021-02-23Clinical Trial Update: Effect of Subcutaneous ACTEMRA on Inflamed Atherosclerotic Plaques in Patients With Rheumatoid Arthritis [Phase 4]
Phase 4 trial assessing subcutaneous ACTEMRA (tocilizumab) on inflamed atherosclerotic plaques in patients with rheumatoid arthritis was ter…
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CLINICAL_TRIALS trial_result · 2021-02-15Clinical Trial Update: Discontinuation of Postmenopausal Hormone Therapy: Impact on the Cardiovascular System and Quality of Life [Phase 4]
Phase 4 trial update on discontinuation of postmenopausal hormone therapy and its effects on cardiovascular outcomes and quality of life.
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CLINICAL_TRIALS trial_result · 2021-01-28Clinical Trial Update: Revacept in Symptomatic Carotid Stenosis [Phase 2]
Phase 2 trial update for Revacept in symptomatic carotid stenosis; results completed and posted.
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CLINICAL_TRIALS trial_result · 2020-11-10Clinical Trial Update: Effect of Low-dose vs. High-dose Pitavastatin on In-stent Restenosis [Phase 4]
Phase 4 trial comparing low-dose versus high-dose pitavastatin effects on in-stent restenosis.
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CLINICAL_TRIALS trial_result · 2020-11-10Clinical Trial Update: Treatment of Patients With Atherosclerotic Disease With Methotrexate-associated to LDL Like Nanoparticles [Phase 2, Phase 3]
Clinical trial update on methotrexate-associated LDL-like nanoparticles for atherosclerotic disease, covering Phase 2 and Phase 3 stages.
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CLINICAL_TRIALS trial_result · 2020-10-27Clinical Trial Update: Treatment of Patients With Atherosclerotic Disease With Paclitaxel-associated to LDL Like Nanoparticles [Phase 2, Phase 3]
Phase 2/Phase 3 trial updating treatment of atherosclerotic disease using paclitaxel-associated LDL-like nanoparticles; status currently unk…
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FDA approval · 2020-10-23FDA Approved: EZETIMIBE — Original Application (ScieGen Pharmaceuticals Inc)
FDA approved ScieGen Pharmaceuticals' original (ANDA) application for ezetimibe as a generic cholesterol-lowering medication.
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CLINICAL_TRIALS trial_result · 2020-09-04Clinical Trial Update: CHOCO-CABANA Trial [Phase 4]
Phase 4 clinical trial update for atherosclerosis under CHOCO-CABANA trial; current status is unknown.
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CLINICAL_TRIALS trial_result · 2020-08-13Clinical Trial Update: Frequent, Low-Dose Erythropoietin A Mechanistic Approach to Mitigate Adverse Cardiovascular Effects of Erythropoietin [Phase 4]
Phase 4 clinical trial on frequent, low-dose erythropoietin to mitigate adverse cardiovascular effects; the study was terminated with result…
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CLINICAL_TRIALS trial_result · 2020-08-06Clinical Trial Update: The Effect of Atorvastatin and Pioglitazone on Carotid Atherosclerosis With the Use of Positron Emission Tomography-computed Tomography (PET-CT) [Phase 4]
Phase 4 trial investigating the effects of atorvastatin and pioglitazone on carotid atherosclerosis assessed by PET-CT; the study status is …
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CLINICAL_TRIALS trial_result · 2020-07-15Clinical Trial Update: RANGER™ Paclitaxel Coated Balloon vs Standard Balloon Angioplasty [Phase 3]
Phase 3 RANGER trial comparing the paclitaxel-coated balloon (RANGER) to standard balloon angioplasty in peripheral artery disease has compl…
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CLINICAL_TRIALS trial_result · 2020-06-23Clinical Trial Update: Validation of a Computed Tomography (CT) Based Fractional Flow Reserve (FFR) Software Using the 320 Detector Aquilion ONE CT Scanner.
A completed clinical trial evaluating a CT-based fractional flow reserve software using a 320-detector Aquilion ONE CT scanner for assessing…
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CLINICAL_TRIALS trial_result · 2020-06-09Clinical Trial Update: Assessment of Coronary Artery Calcium in Active Duty Enlisted Military Members With 10 or More Years of Service
A clinical trial evaluating coronary artery calcium assessment in active duty military members with 10+ years of service; the study is termi…
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CLINICAL_TRIALS trial_result · 2020-05-19Clinical Trial Update: The Lipid-Rich Plaque Study
A completed clinical trial (NCT02033694) investigating lipid-rich plaque in coronary artery disease and atherosclerosis with results posted …
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CLINICAL_TRIALS research · 2020-04-27Clinical Trial Update: Effect of Sarilumab on Atherosclerotic Disease Assessed by PET/CET in Patients With RA (SARIPET) [Phase 4]
Clinical trial update investigating the effect of sarilumab on atherosclerotic disease in patients with rheumatoid arthritis, assessed by PE…
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CLINICAL_TRIALS trial_result · 2020-04-24Clinical Trial Update: Investigating the Effects of Lipid-therapy Intensification With Alirocumab on Endothelial Function, Carotid Arteries, Lipoprotein Particle Subfractions, Inflammation and Post-prandial Lipemia [Phase 4]
Phase 4 trial investigating alirocumab intensification effects on endothelial function, carotid arteries, lipoprotein subfractions, inflamma…
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CLINICAL_TRIALS trial_result · 2020-04-03Clinical Trial Update: Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) as Add-on to Ezetimibe Therapy in Patients With Elevated LDL-C (CLEAR Tranquility) [Phase 3]
Phase 3 trial update assessing bempedoic acid added to ezetimibe for lowering LDL-C in patients with hypercholesterolemia/atherosclerosis.
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CLINICAL_TRIALS trial_result · 2020-03-31Clinical Trial Update: Intensive Rosuvastatin Therapy on Cerebral Hemodynamics in Patients With Atherosclerotic Intracranial Arterial Stenosis [Phase 4]
Phase 4 trial evaluating intensive rosuvastatin therapy on cerebral hemodynamics in patients with atherosclerotic intracranial arterial sten…
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CLINICAL_TRIALS trial_result · 2020-01-22Clinical Trial Update: Cardiovascular Risk Reduction Study (Reduction in Recurrent Major CV Disease Events) [Phase 3]
Phase 3 cardiovascular trial investigating reduction in recurrent major cardiovascular disease events in atherosclerosis; study completed wi…
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CLINICAL_TRIALS trial_result · 2019-12-17Clinical Trial Update: Effects of Worksite Wellness Interventions on Vascular Function, Insulin Sensitivity and High-Density Lipoprotein in Overweight or Obese Women [Phase 2]
Phase 2 trial examining worksite wellness interventions and their effects on vascular function, insulin sensitivity, and HDL in overweight o…
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CLINICAL_TRIALS trial_result · 2019-12-11Clinical Trial Update: A phase3 Study Measuring the Effect of Rosuvastatin 20 mg on Carotid Intima-Media Thickness in Chinese Subjects With Subclinical Atherosclerosis [Phase 3]
Phase 3 trial evaluating rosuvastatin 20 mg on carotid intima-media thickness in Chinese subjects with subclinical atherosclerosis completed…
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CLINICAL_TRIALS withdrawal · 2019-12-11Clinical Trial Update: The Effect of Ticagrelor on 15-Epi-Lipoxin A4 and Inflammation [Phase 4]
A Phase 4 clinical trial investigating ticagrelor's effect on 15-epi-Lipoxin A4 and inflammation in atherosclerosis has been withdrawn.