Atherosclerosis
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CLINICAL_TRIALS trial_result · 2026-08-06Clinical Trial Update: Specifying the Anti-inflammatory Effects of Ziltivekimab [Phase 3]
Phase 3 trial update describing anti-inflammatory effects of Ziltivekimab in atherosclerosis-related inflammation conditions.
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CLINICAL_TRIALS trial_result · 2026-06-04Clinical Trial Results: Ertugliflozin: Cardioprotective Effects on Epicardial Fat [EARLY_Phase 1]
Early-phase trial assessing cardioprotective effects of ertugliflozin on epicardial fat in cardiovascular disease/atherosclerosis contexts; …
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Identification of CETP as a Marker of Atherosclerosis [NA]
Clinical trial update identifying CETP as a biomarker of atherosclerosis. The study is completed.
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Characterization of Patients With Uncommon Presentations and/or Uncommon Diseases Associated With the Cardiovascular System
The NHLBI-funded clinical trial aims to characterize patients with uncommon cardiovascular presentations and diseases, including obesity-rel…
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: The Psoriasis, Atherosclerosis, and Cardiometabolic Disease Initiative (PACI)
An NHLBI-sponsored clinical trial update reports the completion of the Psoriasis, Atherosclerosis, and Cardiometabolic Disease Initiative (P…
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CLINICAL_TRIALS trial_result · 2026-04-22Clinical Trial Update: RESOLUTE ONYX China RCT Study [NA]
Update on the RESOLUTE ONYX China randomized trial; the study is currently active but not recruiting.
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Oral Microbiome in Carotid Atherosclerosis
A recruiting clinical trial is examining how the oral microbiome relates to carotid atherosclerosis, including atherosclerotic cardiovascula…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Subclinical Atherosclerosis in Juvenile Systemic Lupus Erythematosus
A ClinicalTrials.gov listing for a study on subclinical atherosclerosis in juvenile systemic lupus erythematosus, currently not recruiting.
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CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: RESOLUTE ONYX China Single Arm Study [NA]
Clinical trial update for the RESOLUTE ONYX China single-arm study sponsored by Medtronic Vascular; the trial is currently active but not re…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Evaluation of a Diagnostic Software for Coronary Artery Disease Using Retrospective CCTA Data (CODEX-1 Study)
A retrospective study evaluating a diagnostic software (CODEX-1) for detecting coronary artery disease using CCTA data; the trial is current…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: New Heart Imaging Techniques to Evaluate Possible Heart Disease [NA]
This update notes that the National Institute of Diabetes and Digestive and Kidney Diseases is recruiting for a study to evaluate new heart …
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: A Clinical Study of IMC-001 for Injection in Improving Atherosclerotic Plaque Stability in Patients With Acute Coronary Syndrome. [EARLY_Phase 1]
A clinical trial update for IMC-001 in patients with atherosclerosis aiming to improve plaque stability in acute coronary syndrome (early Ph…
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: Cluster Randomized Trial of a Digital Quality Improvement Intervention on LDLCholesterol Control [NA]
A completed cluster randomized trial evaluating a digital quality improvement intervention aimed at improving LDL cholesterol control in peo…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Intravascular Imaging Study of the Effect of Inclisiran on Plaque in Patients With Acute Myocardial Infarction [Phase 4]
A Phase 4 clinical trial evaluating the effect of Inclisiran on atherosclerotic plaque in patients with acute myocardial infarction is curre…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Study of the Effect of Innate on the Inflammatory Response to Endotoxin
A clinical trial assessing the effect of Innate on the inflammatory response to endotoxin; the study is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Strategy for Unstable Coronary Plaque in Patients Presenting to Emergency Department for Chest Pain Suspected of Coronary Artery Disease [NA]
An update on an ongoing clinical trial evaluating strategies for unstable coronary plaque in patients presenting to the emergency department…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Efficacy, Safety, and PopPK Profile of ABP-745 in Patients With Atherosclerosis [Phase 2]
Phase 2 study evaluating ABP-745 for efficacy, safety, and population pharmacokinetics in patients with atherosclerosis and ASCVD.
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: A CCTA Imaging Trial to Evaluate the Effect of Obicetrapib/Ezetimibe on Coronary Plaque [Phase 3]
Phase 3 CCTA imaging trial evaluating the effect of obicetrapib in combination with ezetimibe on coronary plaque; currently ACTIVE_NOT_RECRU…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: A Phase 2b Clinical Trial of YN001 in Adults With Coronary Atherosclerosis [Phase 2]
This entry notes a Phase 2b trial of YN001 in adults with atherosclerosis and coronary artery disease that is currently not yet recruiting.
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: T-Mem GEne in Atherosclerosis
A clinical trial update indicates that the study 'T-Mem GEne in Atherosclerosis' is currently recruiting to evaluate its effects in atherosc…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Fatigue Behavior of Peripheral STENt of the Superficial Femoral Artery
ClinicalTrials.gov update describing a trial evaluating fatigue behavior of a peripheral stent in the superficial femoral artery for atheros…
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CLINICAL_TRIALS trial_result · 2026-04-07Clinical Trial Update: Local Paclitaxel Delivery for SFA Disease [NA]
The University of Oklahoma reports that a clinical trial evaluating local paclitaxel delivery for superficial femoral artery disease has com…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Intracoronary Cryotherapy Effect on Stabilization of Vulnerable Plaque in Patients With Stable Angina or ACS - A Traditional Feasibility Study [NA]
This clinical trial update describes a traditional feasibility study investigating intracoronary cryotherapy to stabilize vulnerable plaque …
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: A Study to Evaluate the Efficacy, Safety, Pharmacodynamics (PD), and Pharmacokinetics (PK) of Selnoflast in Reducing Vascular Inflammation in Participants With Atherosclerosis at Risk for Major Adverse Cardiac Events [Phase 2]
A Phase 2 clinical trial is evaluating the efficacy, safety, pharmacodynamics, and pharmacokinetics of Selnoflast to reduce vascular inflamm…
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CLINICAL_TRIALS trial_result · 2026-03-31Clinical Trial Update: A Real World Evaluation of the ELUVIA Stent in Subjects With Lesions Located in the Femoropopliteal Arteries
A completed real-world study evaluating the ELUVIA zotarolimus-eluting stent in femoropopliteal artery lesions, with results posted.