Astrocytoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: Clinical Benefit of Using Molecular Profiling to Determine an Individualized Treatment Plan for Patients With High Grade Glioma [NA]
A clinical trial update describes using molecular profiling to tailor treatments for patients with high-grade glioma, aiming to improve indi…
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CLINICAL_TRIALS research · 2025-07-03Clinical Trial Update: Adaptive Radiotherapy and MRIs Based on Patients With Newly Diagnosed High-Grade Glioma [NA]
This Columbia University trial assesses adaptive radiotherapy guided by MRI for adults with newly diagnosed high-grade glioma, including gli…
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CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: Evaluation of Eflornithine Plus Temozolomide in Patients With Newly Diagnosed Glioblastoma or Astrocytoma [Phase 1]
Phase 1 trial evaluating the combination of eflornithine and temozolomide in newly diagnosed glioblastoma or astrocytoma; recruitment is ong…
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CLINICAL_TRIALS trial_result · 2025-06-03Clinical Trial Update: Proton Radiotherapy for Pediatric Brain Tumors Requiring Partial Brain Irradiation [Phase 2]
Phase 2 clinical trial evaluating proton radiotherapy for pediatric brain tumors requiring partial brain irradiation has completed enrollmen…
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CLINICAL_TRIALS trial_result · 2025-03-20Clinical Trial Update: Whole-Brain Tumor Burden Metrics with Inflammatory and Molecular Markers to Predict Postoperative Neurocognitive Decline in Glioma
This completed clinical trial evaluated whole-brain tumor burden metrics along with inflammatory and molecular markers to predict postoperat…
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CLINICAL_TRIALS research · 2025-02-21Clinical Trial Update: Study of Olutasidenib and Temozolomide in HGG [Phase 2]
Phase 2 study evaluating olutasidenib in combination with temozolomide for high-grade gliomas is currently recruiting.
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CLINICAL_TRIALS research · 2025-02-19Clinical Trial Update: Insights Into the Pathophysiology of Neurovascular Uncoupling in Patients with Brain Lesions. [NA]
A ClinicalTrials.gov study is currently recruiting to investigate neurovascular uncoupling in patients with brain lesions. The study involve…
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CLINICAL_TRIALS research · 2024-11-29Clinical Trial Update: Study of Safety and Pharmacokinetic Properties of Oral OKN-007 in Patients with Recurrent High-Grade Glioma [Phase 1]
Phase 1 study assessing safety and pharmacokinetics of oral OKN-007 in adults with recurrent high-grade glioma. The trial includes patients …
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CLINICAL_TRIALS research · 2024-11-26Clinical Trial Update: Proton Therapy Research Infrastructure- ProTRAIT- Neuro-oncology
Update on the ProTRAIT proton therapy research infrastructure in neuro-oncology, with ongoing recruitment for several brain tumor conditions…
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CLINICAL_TRIALS trial_result · 2024-11-06Clinical Trial Update: PARP Inhibition for Gliomas (PI-4G or π4g) [Phase 2]
Phase 2 trial of a PARP inhibitor for gliomas was terminated, with results posted in 2024, evaluating recurrent glioblastoma, recurrent astr…
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CLINICAL_TRIALS trial_result · 2024-10-29Clinical Trial Update: Impact of IDH Mutation and Adjuvant Chemo(radio)therapy on Survival Outcome in Grade II/III Astrocytoma
A completed clinical trial update investigating the impact of IDH mutation status and adjuvant chemo(radiotherapy) on survival in Grade II/I…
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CLINICAL_TRIALS research · 2024-08-27Clinical Trial Update: USPIO Enhanced MR Imaging in CNS Tumours (UMIC) [NA]
This clinical trial (UMIC) is evaluating USPIO-enhanced MRI for imaging CNS tumors, including vestibular schwannoma, glioma, and astrocytoma…
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CLINICAL_TRIALS research · 2024-08-06Clinical Trial Update: IDH1 and OCT4 in High Grade Astrocytoma
This clinical trial update indicates a study evaluating IDH1 and OCT4 in high-grade astrocytoma is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-07-05Clinical Trial Update: A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas [Phase 1, Phase 2]
A Phase I/Phase II study evaluating mebendazole for pediatric gliomas has completed. It enrolled children with various glial tumors, includi…
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CLINICAL_TRIALS trial_result · 2023-11-22Clinical Trial Update: Protein Phosphatase 2A Inhibitor, in Recurrent Glioblastoma [Phase 2]
Phase 2 trial evaluating a Protein Phosphatase 2A inhibitor in recurrent glioblastoma and related gliomas completed, with results posted in …
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CLINICAL_TRIALS research · 2023-08-01Clinical Trial Update: Feasibility and Preliminary Efficacy of a Mindfulness-based Intervention for Children and Young Adults With High Grade or High-Risk Cancer and Their Caregivers [NA]
Feasibility and preliminary efficacy study of a mindfulness-based intervention for children and young adults with high-grade or high-risk ca…
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CLINICAL_TRIALS trial_result · 2023-06-29Clinical Trial Update: Study To Test the Safety and Efficacy of TVI-Brain-1 As A Treatment for Recurrent Grade IV Glioma [Phase 2]
Phase 2 trial updating safety and efficacy of TVI-Brain-1 for recurrent grade IV glioma; results posted after completion.
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CLINICAL_TRIALS trial_result · 2023-06-15Clinical Trial Update: TVB- 2640 in Combination With Bevacizumab in Patients With First Relapse of High Grade Astrocytoma [Phase 2]
A Phase 2 trial evaluating TVB-2640 in combination with bevacizumab in first relapse high-grade astrocytoma (astrocytoma). Status completed …
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CLINICAL_TRIALS trial_result · 2020-08-05Clinical Trial Update: Stem Cell Transplant for High Risk Central Nervous System (CNS) Tumors [Phase 2]
Phase 2 clinical trial update on stem cell transplant for high-risk CNS tumors including glioblastoma and astrocytoma; trial completed.
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CLINICAL_TRIALS trial_result · 2020-05-28Clinical Trial Update: Efficacy of Post-radiation Adjuvant Temozolomide Chemotherapy in Residue Low-grade Glioma [Phase 3]
Phase 3 trial evaluating post-radiation adjuvant temozolomide chemotherapy for residue low-grade glioma; recruiting status suggests ongoing …
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CLINICAL_TRIALS trial_result · 2020-03-26Clinical Trial Update: Nivolumab With DC Vaccines for Recurrent Brain Tumors [Phase 1]
Phase 1 trial evaluating nivolumab in combination with dendritic cell vaccines for recurrent brain tumors has completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-01-27Clinical Trial Update: First in Patient Study for PF-06840003 in Malignant Gliomas [Phase 1]
Phase 1 trial update for PF-06840003 in malignant gliomas has been terminated; results posted.
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CLINICAL_TRIALS trial_result · 2019-11-12Clinical Trial Update: Hyperfractionated RT With BCNU Versus Conventional RT With BCNU for Supratentorial Malignant Glioma [Phase 3]
Phase 3 trial comparing hyperfractionated radiotherapy with BCNU to conventional radiotherapy with BCNU in supratentorial malignant glioma.
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CLINICAL_TRIALS trial_result · 2019-07-24Clinical Trial Update: Safety and Efficacy Study of TH-302 CNS Penetration in Recurrent High Grade Astrocytoma Following Bevacizumab [Phase 2]
Phase 2 clinical trial updating safety and efficacy of TH-302 CNS penetration in recurrent high-grade astrocytoma after bevacizumab, complet…
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CLINICAL_TRIALS research · 2019-02-21Clinical Trial Update: A Prospective Cohort to Study the Effect of Temozolomide on IDH Mutational Low Grade Gliomas [Phase 2]
A Phase 2 prospective cohort study evaluating the effect of temozolomide on IDH-mutant low-grade gliomas (astrocytoma, oligodendroglioma, an…