Astrocytoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-01-05Clinical Trial Update: Phase I Study of Orally Administered Aminolevulinic Acid for Resection of Malignant Astrocytomas [Phase 1]
A Phase I study at Johns Hopkins evaluated orally administered aminolevulinic acid for fluorescence-guided resection of malignant astrocytom…
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CLINICAL_TRIALS trial_result · 2016-11-15Clinical Trial Update: Temozolomide All-Case-Registered Surveillance (Designated Drug Use Investigation)(Study P05062)
Clinical trial update for Temozolomide all-case surveillance (P05062) notes that the study status is COMPLETED and collected surveillance da…
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CLINICAL_TRIALS trial_result · 2016-10-21Clinical Trial Update: Evaluation of FDOPA-PET/MRI in Pediatric Patients With CNS Tumors [Phase 1]
Phase 1 trial evaluating FDOPA-PET/MRI imaging in pediatric CNS tumors has completed the Phase 1 portion.
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CLINICAL_TRIALS trial_result · 2016-03-17Clinical Trial Update: A Study of Aminolevulinic Acid Used to Enhance Visualization and Surgical Removal of Brain Tumors [Phase 2]
Phase 2 study evaluating aminolevulinic acid to enhance visualization and surgical removal of brain tumors has been terminated.
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CLINICAL_TRIALS trial_result · 2016-03-07Clinical Trial Update: AZD2171 in Treating Young Patients With Recurrent, Progressive, or Refractory Primary CNS Tumors [Phase 1]
Phase 1 study of AZD2171 (cediranib) in children with recurrent, progressive, or refractory primary central nervous system tumors has comple…
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CLINICAL_TRIALS trial_result · 2016-03-02Clinical Trial Update: A Phase I Dose Finding and Safety Study of Oral LDE225 in Children and a Phase II Portion to Assess Preliminary Efficacy in Recurrent or Refractory MB [Phase 1, Phase 2]
Phase I dose-finding and safety study of LDE225 (sonidegib) in children with recurrent or refractory medulloblastoma, with a Phase II portio…
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CLINICAL_TRIALS trial_result · 2016-02-02Clinical Trial Update: Everolimus (RAD001) for Children With Chemotherapy-Refractory Progressive or Recurrent Low-Grade Gliomas [Phase 2]
Phase 2 trial evaluating everolimus (RAD001) in children with chemotherapy-refractory progressive or recurrent low-grade gliomas has complet…
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CLINICAL_TRIALS trial_result · 2015-12-08Clinical Trial Update: HLA-A2-Restricted Glioma Antigen-Peptides Vaccinations With Poly-ICLC for Recurrent WHO Grade II Gliomas [EARLY_Phase 1]
An early Phase 1 trial evaluating an HLA-A2-restricted glioma antigen-peptide vaccine with Poly-ICLC in recurrent WHO Grade II gliomas (astr…
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CLINICAL_TRIALS trial_result · 2014-08-05Clinical Trial Update: Treatment Strategy for Low-grade Gliomas [Phase 3]
A Phase 3 trial for low-grade gliomas has been terminated, involving astrocytoma, oligodendroglioma, and oligoastrocytoma.
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CLINICAL_TRIALS trial_result · 2014-02-21Clinical Trial Update: Chemotherapy and Radiation Therapy After Surgery in Treating Children With Newly Diagnosed Astrocytoma, Glioblastoma Multiforme, Gliosarcoma, or Diffuse Intrinsic Pontine Glioma [Phase 2]
A phase 2 trial evaluating chemotherapy and radiation therapy after surgery in children with newly diagnosed astrocytoma, glioblastoma multi…
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CLINICAL_TRIALS trial_result · 2013-12-20Clinical Trial Update: Efficacy of Protracted Temozolomide in Patients With Progressive High Grade Glioma [Phase 2]
This Phase 2 clinical trial evaluates the efficacy of protracted temozolomide in patients with progressive high-grade glioma, including glio…
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CLINICAL_TRIALS trial_result · 2013-12-18Clinical Trial Update: IL-4(38-37)-PE38KDEL Immunotoxin in Treating Patients With Recurrent Malignant Astrocytoma [Phase 1]
A Phase 1 clinical trial evaluates the IL-4(38-37)-PE38KDEL immunotoxin for recurrent malignant astrocytoma, sponsored by Barrett Cancer Cen…
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CLINICAL_TRIALS trial_result · 2013-12-04Clinical Trial Update: A Study to Evaluate the Efficacy of Bevacizumab Plus Irinotecan in Recurrent Gliomas [Phase 2]
A Phase 2 trial evaluating bevacizumab plus irinotecan in recurrent gliomas (glioblastoma and astrocytoma) has completed.
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CLINICAL_TRIALS trial_result · 2013-09-30Clinical Trial Update: Lenalidomide in Treating Young Patients With Recurrent, Progressive, or Refractory CNS Tumors [Phase 1]
A Phase 1 clinical trial evaluated lenalidomide in young patients with recurrent, progressive, or refractory central nervous system tumors. …
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CLINICAL_TRIALS trial_result · 2013-06-05Clinical Trial Update: Erlotinib and Temozolomide in Treating Young Patients With Recurrent or Refractory Solid Tumors [Phase 1]
Phase 1 study evaluating the combination of erlotinib and temozolomide in pediatric patients with recurrent or refractory solid tumors has c…
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CLINICAL_TRIALS trial_result · 2013-04-05Clinical Trial Update: Biological Therapy Following Surgery and Radiation Therapy in Treating Patients With Primary or Recurrent Astrocytoma or Oligodendroglioma [Phase 2]
A Phase 2 clinical trial of a biological therapy following surgery and radiation for primary or recurrent Astrocytoma or Oligodendroglioma h…
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CLINICAL_TRIALS trial_result · 2013-02-18Clinical Trial Update: Combination Chemotherapy in Treating Children With Astrocytomas and Primitive Neuroectodermal Tumors [Phase 2]
A Phase 2 clinical trial evaluated combination chemotherapy for children with astrocytomas and primitive neuroectodermal tumors; the study s…
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CLINICAL_TRIALS trial_result · 2013-01-08Clinical Trial Update: Temodal (Temozolomide) Post Marketing Surveillance Protocol (Study P05557AM2)
This is a post-marketing surveillance protocol update for Temozolomide (Temodal) in patients with glioblastoma, glioma, and astrocytoma; the…
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CLINICAL_TRIALS trial_result · 2012-08-02Clinical Trial Update: Efficacy of Tranexamic Acid in Brain Tumor Resections [Phase 3]
Phase 3 clinical trial update evaluating the efficacy of tranexamic acid during brain tumor resections.
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CLINICAL_TRIALS trial_result · 2012-07-27Clinical Trial Update: Exploratory Study of XL765 (SAR245409) or XL147 (SAR245408) in Subjects With Recurrent Glioblastoma Who Are Candidates for Surgical Resection [Phase 1]
Phase 1 exploratory study evaluating two investigational PI3K/mTOR inhibitors, XL765 (SAR245409) and XL147 (SAR245408), in patients with rec…
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CLINICAL_TRIALS trial_result · 2012-05-04Clinical Trial Update: Assessment of 18FLT PET-CT for Volume Definition of High-grade Gliomas (GLIO-TEP) [Phase 1, Phase 2]
This clinical trial update assesses 18F-FLT PET-CT for defining tumor volumes in high-grade gliomas, including astrocytoma and glioblastoma,…
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CLINICAL_TRIALS trial_result · 2012-02-09Clinical Trial Update: A Phase II Study of Temozolomide and O6-Benzylguanine (O6-BG) in Patients With Temozolomide-Resistant Anaplastic Glioma [Phase 2]
This Phase II study evaluating temozolomide in combination with O6-benzylguanine for temozolomide-resistant anaplastic glioma was terminated…
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CLINICAL_TRIALS trial_result · 2011-02-02Clinical Trial Update: Study of Imatinib Mesylate in Combination With Hydroxyurea Versus Hydroxyurea Alone as an Oral Therapy in Patients With Temozolomide Resistant Progressive Glioblastoma [Phase 3]
Phase 3 trial comparing imatinib mesylate with hydroxyurea versus hydroxyurea alone in temozolomide-resistant progressive glioblastoma; stud…
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CLINICAL_TRIALS trial_result · 2010-05-17Clinical Trial Update: The Effects of Continuous 28-day (28/28) Temozolomide Chemotherapy in Subjects With Recurrent Malignant Glioma Who Have Failed the Conventional 5-day (5/28) Treatment (P04601) [Phase 2]
Phase 2 trial evaluating continuous 28-day temozolomide in patients with recurrent malignant glioma who failed the standard 5-day regimen; r…
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CLINICAL_TRIALS trial_result · 2009-11-02Clinical Trial Update: Prolonged Daily Temozolomide for Low-Grade Glioma [Phase 2]
Phase 2 trial results from Dana-Farber Cancer Institute evaluate prolonged daily temozolomide in patients with low-grade glioma, including a…