Apnea of Prematurity
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-07Clinical Trial Update: Caffeine Citrate in Preterm Infants at Risk of Apnea in Zambia [Phase 4]
A Phase 4 clinical trial in Zambia evaluating caffeine citrate to prevent apnea in premature infants is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-30Clinical Trial Update: Apnea Treatment in Premature Infants Using an Automatic Vibro-tactile Stimulator Triggered by the Detection of Apnea-bradycardia. [NA]
A completed clinical trial tested an automatic vibro-tactile stimulator triggered by apnea-bradycardia to treat apnea of prematurity in prem…
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CLINICAL_TRIALS trial_result · 2025-11-10Clinical Trial Update: Caffeine Use in the Management of Preterm Infants [Phase 2]
This document notes a Phase 2 clinical trial evaluating caffeine citrate for the management of apnea of prematurity; the study status is act…
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CLINICAL_TRIALS trial_result · 2025-04-04Clinical Trial Update: Nasal Olfactory Stimulation and Its Effect on Respiratory Drive in Preterm Infants [NA]
This clinical trial update notes that the study on nasal olfactory stimulation and its effect on respiratory drive in preterm infants has co…
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CLINICAL_TRIALS trial_result · 2025-04-01Clinical Trial Update: Apnea of Prematurity Results in Respiratory Distress and Cyanosis. Caffeine Citrate Can Treat It. [Phase 1]
Phase 1 trial investigates caffeine citrate as a treatment for apnea of prematurity, noting respiratory distress and cyanosis associated wit…
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CLINICAL_TRIALS trial_result · 2025-02-14Clinical Trial Update: Role of Interleukin-1β and Prostaglandin E2 in Prediction and Outcome of Apnea in Neonates
A completed clinical trial investigates whether interleukin-1β and prostaglandin E2 can predict apnea and influence its outcomes in prematur…
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CLINICAL_TRIALS trial_result · 2025-01-29Clinical Trial Update: Non-Invasive Neurally Adjusted Ventilatory Assist (NAVA) Prone vs Supine in Premature Infants [NA]
This update reports completion of a clinical trial evaluating prone vs. supine positioning using Non-Invasive Neurally Adjusted Ventilatory …
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CLINICAL_TRIALS trial_result · 2024-10-15Clinical Trial Update: Pilot Study to Evaluate Doses of Mechanical Stimulus on the Effectiveness of Preterm Breathing [NA]
A completed pilot clinical trial evaluating different doses of a mechanical stimulus to improve preterm breathing in infants with apnea of p…
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CLINICAL_TRIALS trial_result · 2024-07-30Clinical Trial Update: CPAP vs.Unsynchronized NIPPV at Equal Mean Airway Pressure [NA]
A clinical trial comparing CPAP versus unsynchronized NIPPV at equal mean airway pressure in premature infants with respiratory distress syn…
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CLINICAL_TRIALS trial_result · 2024-07-08Clinical Trial Update: Effect of High Frequency Oscillatory Highflow Nasal Cannula on Desaturations and Bradycardia in Preterm Infants [NA]
A completed clinical trial evaluating the effect of a high-frequency oscillatory high-flow nasal cannula on desaturation and bradycardia in …
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CLINICAL_TRIALS trial_result · 2024-06-28Clinical Trial Update: Moderately Preterm Infants With Caffeine at Home for Apnea (MoCHA) Trial [Phase 3]
A Phase 3 trial (MoCHA) evaluating caffeine citrate for apnea of prematurity in moderately preterm infants was terminated; results have been…
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CLINICAL_TRIALS trial_result · 2024-04-04Clinical Trial Update: Doxapram Therapy in Preterm Infants (DOXA Trial) [Phase 3]
Phase 3 trial update for doxapram therapy in preterm infants with apnea of prematurity and respiratory insufficiency; currently recruiting.
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CLINICAL_TRIALS trial_result · 2023-10-18Clinical Trial Update: Target Weaning Oxygen to Determine Cafffeine Duration for AOP [Phase 4]
Phase 4 trial updating caffeine duration based on oxygen weaning in apnea of prematurity has completed.
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CLINICAL_TRIALS trial_result · 2021-08-03Clinical Trial Update: Early Caffeine in Preterm Neonates [Phase 4]
A Phase 4 clinical trial update on early caffeine use in preterm neonates for bronchopulmonary dysplasia and apnea of prematurity; current s…
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CLINICAL_TRIALS trial_result · 2020-03-17Clinical Trial Update: A Comparison of Methods of Discontinuing Nasal CPAP in Premature Infants <30 Weeks Gestation [NA]
A completed clinical trial comparing methods for discontinuing nasal CPAP in premature infants under 30 weeks gestation; results posted in 2…
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CLINICAL_TRIALS trial_result · 2020-02-07Clinical Trial Update: A Comparison of Non-invasive Ventilation Methods Used to Prevent Endotracheal Intubation Due to Apnea in Very Low Birth Weight Infants [NA]
A completed clinical trial comparing non-invasive ventilation methods to prevent endotracheal intubation due to apnea in very low birth weig…
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CLINICAL_TRIALS trial_result · 2018-03-22Clinical Trial Update: Caffeine for Apnea of Prematurity (CAP) [Phase 3]
A Phase 3 trial evaluating caffeine citrate for apnea of prematurity has completed.
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CLINICAL_TRIALS trial_result · 2017-06-19Clinical Trial Update: Caffeine to Reduce Mechanical Ventilation in Preterm Infants [NA]
Terminated clinical trial evaluating caffeine citrate to reduce the need for mechanical ventilation in preterm infants; results were posted …
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CLINICAL_TRIALS trial_result · 2017-05-09Clinical Trial Update: Non-invasive Intervention for Apnea of Prematurity [NA]
A completed UCLA-sponsored clinical trial tested a non-invasive intervention for apnea of prematurity and related hypoxia and bradycardia; r…
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CLINICAL_TRIALS trial_result · 2017-03-21Clinical Trial Update: Effect of Caffeine on Preterm Infants' Bone Mineral Content
A completed clinical trial evaluated the impact of caffeine citrate on bone mineral content in preterm infants. It also examined apnea of pr…
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CLINICAL_TRIALS trial_result · 2017-03-08Clinical Trial Update: Nasogastric Versus Orogastric Route of Feeding in Preterm (<32 Weeks) Neonates [NA]
A completed clinical trial comparing nasogastric versus orogastric feeding in preterm neonates (<32 weeks).
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CLINICAL_TRIALS trial_result · 2017-02-27Clinical Trial Update: Dosing Chart for Calculating the First Dose of Doxapram in Premature Infants [Phase 4]
Phase 4 trial update provides dosing chart guidance for calculating the first dose of doxapram in premature infants with apnea of prematurit…
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CLINICAL_TRIALS trial_result · 2016-02-24Clinical Trial Update: MRI and Neurodevelopment in Preterm Infants Following Administration of High-Dose Caffeine [Phase 4]
Phase 4 clinical trial update examining MRI findings and neurodevelopment in preterm infants treated with high-dose caffeine for apnea of pr…
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CLINICAL_TRIALS trial_result · 2015-10-15Clinical Trial Update: Effects of Non-Nutritive Sucking on Gastroesophageal Reflux and Related Apneas in Symptomatic Preterm Infants
A completed clinical trial evaluating whether non-nutritive sucking affects gastroesophageal reflux and related apneas in symptomatic preter…
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CLINICAL_TRIALS trial_result · 2015-09-10Clinical Trial Update: Stochastic Resonance Mattress (Physiological Interventions) and Biomarkers for Enhancing Neonatal Health
A completed clinical trial evaluating a stochastic resonance mattress and biomarkers to enhance neonatal health in apnea of prematurity.