Aortic Valve Stenosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-08-06Clinical Trial Update: Perioperative Hemodynamic and Microcirculatory Physiological Study During TAVI
The trial NCT06154642 evaluating perioperative hemodynamic and microcirculatory physiology during transcatheter aortic valve implantation fo…
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CLINICAL_TRIALS other · 2024-07-23Clinical Trial Update: DurAVR™ THV EU-EFS [NA]
This clinical trial update indicates that the DurAVR transcatheter heart valve trial in Europe is not yet recruiting for symptomatic/severe …
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CLINICAL_TRIALS other · 2024-07-05Clinical Trial Update: Hydra Single-centre Experience - Copenhagen, Denmark
This update describes the Hydra single-centre experience in Copenhagen for aortic valve stenosis and notes that the trial is currently recru…
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CLINICAL_TRIALS research · 2024-07-01Clinical Trial Update: Avalus European Registry - an Observational Study to Evaluate Safety and Efficacy in a Real World Population
This entry describes the Avalus European Registry, an observational study to assess safety and effectiveness of the Avalus transcatheter aor…
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CLINICAL_TRIALS research · 2024-06-21Clinical Trial Update: The Role of SGLT2i in Management of Moderate AS [Phase 2, Phase 3]
Ongoing Phase 2 and Phase 3 study, sponsored by the University of East Anglia, evaluating SGLT2 inhibitors for moderate aortic valve stenosi…
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CLINICAL_TRIALS trial_result · 2024-06-11Clinical Trial Update: BIOVALVE - I / II Clincial Investigation [NA]
This document reports a completed BIOVALVE I/II clinical investigation sponsored by Biotronik AG. The study evaluated valvular heart disease…
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CLINICAL_TRIALS research · 2024-06-03Clinical Trial Update: European Association of Cardiovascular Imaging Multiple and Mixed Valvular Disease Study
Update on an ongoing European cardiovascular imaging study investigating multivalvular heart disease; recruitment is currently ongoing.
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CLINICAL_TRIALS trial_result · 2024-05-31Clinical Trial Update: Periprocedural Continuation Versus Interruption of Oral Anticoagulant Drugs During Transcatheter Aortic Valve Implantation (POPular PAUSE TAVI) [Phase 4]
Phase 4 POPular PAUSE TAVI trial update comparing continuation versus interruption of oral anticoagulant therapy around transcatheter aortic…
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CLINICAL_TRIALS trial_result · 2024-05-22Clinical Trial Update: WATCH-TAVR, WATCHMAN for Patients With Atrial Fibrillation Undergoing Transcatheter Aortic Valve Replacement [NA]
The WATCH-TAVR trial evaluating the WATCHMAN left atrial appendage closure device in patients with atrial fibrillation undergoing transcathe…
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CLINICAL_TRIALS research · 2024-05-08Clinical Trial Update: Prospective Project to Identify Biomarkers of Morbidity and Mortality in Cardiovascular Interventional Patients
A prospective study led by the University of Turku to identify biomarkers of morbidity and mortality in cardiovascular interventional patien…
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CLINICAL_TRIALS research · 2024-04-26Clinical Trial Update: Randomized Trial of TAVI vs. SAVR in Patients With Severe Aortic Valve Stenosis at Low to Intermediate Risk of Mortality [NA]
This entry provides an update on a randomized trial comparing transcatheter aortic valve implantation (TAVI) versus surgical aortic valve re…
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CLINICAL_TRIALS trial_result · 2024-04-26Clinical Trial Update: Cerebrovascular EveNts in Patients Undergoing TranscathetER Aortic Valve Implantation With Balloon-expandable Valves Versus Self-expandable Valves.
A completed clinical trial evaluating cerebrovascular events in patients undergoing transcatheter aortic valve implantation with balloon-exp…
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CLINICAL_TRIALS research · 2024-04-25Clinical Trial Update: Personalized, CT-guided Antithrombotic Therapy Versus Lifelong Single Antiplatelet Therapy to Reduce Thromboembolic and Bleeding Events in Non-atrial Fibrillation Patients After Transcatheter Aortic Valve Implantation [NA]
A clinical trial comparing CT-guided antithrombotic therapy versus lifelong single antiplatelet therapy after transcatheter aortic valve imp…
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CLINICAL_TRIALS trial_result · 2024-03-20Clinical Trial Update: PROACT Xa - A Trial to Determine if Participants With an On-X Aortic Valve Can be Maintained Safely on Apixaban [Phase 3]
Phase 3 trial PROACT Xa evaluating whether patients with On-X aortic valves can be safely maintained on apixaban; the study was terminated w…
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CLINICAL_TRIALS trial_result · 2024-01-10Clinical Trial Update: Medtronic Evolut™ EXPAND TAVR I Feasibility Study [NA]
Clinical feasibility study for Medtronic Evolut EXPAND TAVR I was terminated; results posted.
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CLINICAL_TRIALS withdrawal · 2023-03-17Clinical Trial Update: Efficacy of Angiotensin Receptor Blocker Following aortIc Valve Intervention for Aortic STenOsis: a Randomized mulTi-cEntric Double-blind Phase II Study [Phase 2, Phase 3]
A randomized, multicenter, double-blind Phase II/III trial evaluating an angiotensin receptor blocker after aortic valve intervention was wi…
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CLINICAL_TRIALS trial_result · 2023-02-16Clinical Trial Update: Assessing the Incidence of Postoperative Delirium Following Aortic Valve Replacement
A completed clinical trial evaluating the incidence of postoperative delirium after aortic valve replacement.
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CLINICAL_TRIALS trial_result · 2022-12-27Clinical Trial Update: REPRISE IV: LOTUS Edge Valve System in Intermediate Surgical Risk Subjects [NA]
Clinical trial update for REPRISE IV evaluating the LOTUS Edge Valve System in intermediate surgical risk patients with aortic valve stenosi…
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CLINICAL_TRIALS trial_result · 2022-11-22Clinical Trial Update: JENAVALVE AS EFS TRIAL: Pericardial TAVR Aortic Stenosis Study [NA]
Clinical trial update for the JenaValve EFS trial in pericardial TAVR for aortic stenosis; status unknown with results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-07-27Clinical Trial Update: Rotterdam EDOXaban Leaflet Evaluation in Patients After Transcatheter Aortic Valve Implantation [Phase 3]
Phase 3 trial update evaluating edoxaban leaflet evaluation after transcatheter aortic valve implantation for patients with aortic valve ste…
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CLINICAL_TRIALS trial_result · 2022-04-04Clinical Trial Update: Impact of Local Tissue Inflammation on Intramyocardial Conduction Pathways Post Percutaneous Valve : Evaluation by Positron Emission Tomography on Exploratory Cohort [Phase 2]
Phase 2 exploratory trial evaluating how local tissue inflammation affects intramyocardial conduction after percutaneous valve intervention …
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CLINICAL_TRIALS trial_result · 2022-03-31Clinical Trial Update: Single Antiplatelet Treatment With Ticagrelor or Aspirin After Transcatheter Aortic Valve Implantation [Phase 4]
Phase 4 trial evaluating single antiplatelet therapy with ticagrelor or aspirin following transcatheter aortic valve implantation.
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CLINICAL_TRIALS trial_result · 2022-03-08Clinical Trial Update: Anticoagulation for Aortic Bioprosthesis (ANTIPRO) [Phase 4]
Phase 4 clinical trial update on anticoagulation for patients with aortic valve bioprostheses completed.
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CLINICAL_TRIALS trial_result · 2022-02-14Clinical Trial Update: Safety Profile Evaluation of TICagrelor Alone Compared to a Combination of Lysine Acetylsalicylate-Clopidogrel in the Context of Transcatheter Aortic Valve Implantation (TAVI) [Phase 3]
Phase 3 trial evaluating safety of ticagrelor alone versus a combination of lysine acetylsalicylate-clopidogrel in patients undergoing trans…
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CLINICAL_TRIALS trial_result · 2022-01-24Clinical Trial Update: 5 Year Observation of Patients With PORTICO Valves
This update presents five-year follow-up results from patients treated with the PORTICO transcatheter aortic valve for aortic valve stenosis…