Aortic Valve Stenosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: LANDMARK Trial: a Randomised Controlled Trial of Myval THV [NA]
LANDMARK trial is a randomized controlled trial evaluating the Myval transcatheter heart valve for aortic valve stenosis and is currently re…
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CLINICAL_TRIALS trial_result · 2025-03-30Clinical Trial Update: Evaluation of Intraoperative Dexmedetomidine Use in Patients Undergoing Surgical Aortic Valve Replacement [Phase 3]
Phase 3 trial evaluating intraoperative dexmedetomidine use in patients undergoing surgical aortic valve replacement has completed.
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CLINICAL_TRIALS research · 2025-03-27Clinical Trial Update: Observational Study Relating to the Long-term Follow-up of Patients with Severe Aortic Stenosis Evaluated for Percutaneous Aortic Valve Replacement (TAVI).
This is an observational long-term follow-up study of patients with aortic valve stenosis evaluated for transcatheter aortic valve replaceme…
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CLINICAL_TRIALS research · 2025-03-26Clinical Trial Update: TAVR: The Impact of Prothesis Positioning on Valvular and Coronary Hemodynamics [NA]
This clinical trial update examines how prosthesis positioning in transcatheter aortic valve replacement affects valvular and coronary hemod…
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CLINICAL_TRIALS research · 2025-03-21Clinical Trial Update: Effect of Fetal Aortic Valvuloplasty on Outcomes
A clinical trial update indicates ongoing recruitment for a study evaluating the effect of fetal aortic valvuloplasty on outcomes in fetuses…
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CLINICAL_TRIALS research · 2025-03-21Clinical Trial Update: Functional Assessment in TAVI: FAITAVI [NA]
Clinical trial update for FAITAVI, a study on functional assessment in transcatheter aortic valve implantation (TAVI), currently active but …
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CLINICAL_TRIALS research · 2025-03-13Clinical Trial Update: Transcatheter Aortic Valve Implantation Registry at the National Research Center for Cardiac Surgery, Nur-Sultan, Kazakhstan [NA]
A registry update indicates ongoing recruitment for Transcatheter Aortic Valve Implantation at the National Research Center for Cardiac Surg…
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CLINICAL_TRIALS trial_result · 2025-03-05Clinical Trial Update: In-vitro Benchmarking of Currently Available Heart Valve Prostheses for Surgical and Percutaneous Treatment of Aortic Stenosis With Small Annulus, Followed by In-vivo Validation [NA]
This clinical trial update describes in-vitro benchmarking of currently available heart valve prostheses for surgical and percutaneous treat…
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CLINICAL_TRIALS trial_result · 2025-02-28Clinical Trial Update: Portico Valve-in-Valve Retrospective Registry
A retrospective registry of Portico valve-in-valve procedures for failing aortic valves, with results posted on 2025-02-28.
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CLINICAL_TRIALS research · 2025-02-28Clinical Trial Update: The Leaflex™ Standalone Study Protocol [NA]
This document provides an update on the Leaflex standalone study protocol sponsored by Pi-cardia for aortic valve stenosis, noting that the …
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CLINICAL_TRIALS research · 2025-02-19Clinical Trial Update: Hydra Registry - UK
A clinical trial registry entry for the Hydra Registry in the United Kingdom, sponsored by Sahajanand Medical Technologies Limited, recruiti…
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CLINICAL_TRIALS trial_result · 2025-02-12Clinical Trial Update: Screening for Amyloidosis Before Aortic Valve Elective Replacement
Charite University in Berlin is screening for amyloidosis in patients undergoing elective aortic valve replacement; the trial (NCT04869631) …
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CLINICAL_TRIALS other · 2025-02-11Clinical Trial Update: J-Valve Compassionate Use
The compassionate-use program for the J-Valve device is no longer available.
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CLINICAL_TRIALS research · 2025-02-10Clinical Trial Update: Bicuspid Aortic Valve Replacement: Evaluation of Transcatheter Versus Surgery-Pilot Trial [NA]
Pilot trial evaluating transcatheter versus surgical replacement for bicuspid aortic valve in patients with aortic valve stenosis; currently…
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: The ShortCut™ Study Protocol [NA]
The ShortCut study protocol has completed and posted results related to evaluating risk of coronary obstruction after transcatheter aortic v…
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CLINICAL_TRIALS research · 2025-02-03Clinical Trial Update: MYVAL Transcatheter Heart Valve System - Prospective German Multicenter Registry
Prospective German multicenter registry evaluating the MYVAL Transcatheter Heart Valve System for treatment of aortic valve stenosis; curren…
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CLINICAL_TRIALS trial_result · 2025-01-07Clinical Trial Update: EArly Effect of Glucocorticoid on Incidence of Persistent Left BundlE Branch Block (LBBB) Post-TAVR (EAGLE-TAVR Trial) [Phase 4]
Phase 4 clinical trial (EAGLE-TAVR) evaluating whether glucocorticoids affect the incidence of persistent left bundle branch block after tra…
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CLINICAL_TRIALS trial_result · 2025-01-06Clinical Trial Update: Novel Echocardiographic and Invasive Haemodynamic Measurements in the Assessment of Patients Low Flow Low Gradient Aortic Stenosis Undergoing TAVI [NA]
Clinical trial update describing novel echocardiographic and invasive haemodynamic measurements used to assess patients with low-flow, low-g…
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CLINICAL_TRIALS research · 2025-01-03Clinical Trial Update: Myval TransAXillary Transcatheter Aortic Valve Replacement Multicenter Clinical Registry
Clinical trial registry update for a multicenter registry evaluating the Myval TransAXillary Transcatheter Aortic Valve Replacement for aort…
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CLINICAL_TRIALS research · 2024-12-30Clinical Trial Update: Clinical Trial Evaluating the Safety and Efficacy of Artificial Polymer Heart Valve for the Treatment of Aortic Valve Disease [NA]
A clinical trial is evaluating the safety and efficacy of an artificial polymer heart valve for aortic valve disease, but the study has not …
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CLINICAL_TRIALS research · 2024-12-16Clinical Trial Update: Percutaneous Coronary Intervention Before Transcatheter Aortic Valve Implantation [NA]
The trial examining percutaneous coronary intervention before transcatheter aortic valve implantation is currently active but not recruiting…
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CLINICAL_TRIALS trial_result · 2024-12-16Clinical Trial Update: Evaluating the Safety and Efficacy of Prosthetic Polymer Heart Valves for the Treatment of Aortic Valve Disease [NA]
A clinical trial evaluating the safety and efficacy of a prosthetic polymer heart valve for aortic valve disease is currently enrolling by i…
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CLINICAL_TRIALS research · 2024-12-10Clinical Trial Update: Comparison of Left Bundle Branch Area Versus Right Ventricular Septal Pacing in Patients With High-degree Conduction Disease After Transcatheter Aortic Valve Replacement (Left Bundle BRAVE) [NA]
This entry provides an update on the Left Bundle BRAVE trial comparing left bundle branch area pacing versus right ventricular septal pacing…
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CLINICAL_TRIALS research · 2024-12-09Clinical Trial Update: Impact of Beta Blockers on TAVI (BETA-TAVI) [Phase 4]
Phase 4 clinical trial update evaluating the impact of beta blockers on outcomes after transcatheter aortic valve implantation in patients w…
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CLINICAL_TRIALS research · 2024-12-09Clinical Trial Update: Aortic Stenosis: Determinants and Prognostic Value of Preoperative Left Ventricular Remodeling After Valvular Replacement
This clinical trial update reports on determinants and the prognostic value of preoperative left ventricular remodeling after valvular repla…