Aortic Valve Stenosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: NVT ALLEGRA TAVI System TF in Failing Calcified Aortic Heart Valves in a Real-world Patient Population
Clinical trial update for the NVT Allegra TAVI System TF in patients with failing calcified aortic valves; the study is active but not recru…
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CLINICAL_TRIALS withdrawal · 2025-10-27Clinical Trial Update: The Leaflex™ Early Feasibility Study [NA]
The Leaflex Early Feasibility Study for aortic valve stenosis has been withdrawn.
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CLINICAL_TRIALS research · 2025-10-10Clinical Trial Update: ENVISION IDE Trial: Safety and Effectiveness of NAVITOR in Transcatheter Aortic Valve Implantation [NA]
The ENVISION IDE trial is evaluating the safety and effectiveness of NAVITOR for transcatheter aortic valve implantation in patients with ao…
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CLINICAL_TRIALS research · 2025-10-03Clinical Trial Update: IcoSApent ethyL to Slow Down Aortic VAlve Stenosis proGrEssion [Phase 2]
A Phase 2 trial update examining whether icosapent ethyl can slow progression of aortic valve stenosis; the study is currently active but no…
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CLINICAL_TRIALS trial_result · 2025-09-30Clinical Trial Update: TAVI Without Balloon Predilatation (of the Aortic Valve ) SAPIEN 3 [NA]
Clinical Trial Update indicates the completion of a study evaluating transcatheter aortic valve implantation without balloon predilatation u…
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: FIH Study of the GEMINUS TAVI System in Patients With Severe Symptomatic Aortic Stenosis [NA]
First-in-human study update for the GEMINUS TAVI System in severe symptomatic aortic stenosis; trial is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-09-16Clinical Trial Update: Monitored Anesthesia Care vs. General Anesthesia for Transcatheter Aortic Valve Replacement [NA]
A completed clinical trial comparing monitored anesthesia care to general anesthesia for transcatheter aortic valve replacement.
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: Colchicine and Inflammation in Aortic Stenosis [Phase 3]
This is an update on a Phase 3 clinical trial studying colchicine for inflammation in aortic valve disease, currently active but not recruit…
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CLINICAL_TRIALS trial_result · 2025-09-10Clinical Trial Update: Measurement of Myocardial Stiffness Using Elastometry in Patients With Aortic Stenosis [NA]
This is a completed clinical trial investigating measurement of myocardial stiffness using elastometry in patients with aortic valve stenosi…
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CLINICAL_TRIALS trial_result · 2025-09-09Clinical Trial Update: FORWARD PRO Study Interventional Post-market Study With the Evolut™ PRO System
A post-market interventional study of the Evolut PRO transcatheter aortic valve replacement system has completed.
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: Early Valve Replacement Guided by Biomarkers of LV Decompensation in Asymptomatic Patients With Severe AS [NA]
This update describes a clinical trial examining early valve replacement guided by biomarkers of left ventricular decompensation in asymptom…
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: ROTAO 1 - Feasibility and Safety of the TAVIPILOT Tele-operated Robot During Transcatheter Aortic Valve Replacement (TAVR/TAVI) [NA]
This clinical trial update describes the feasibility and safety of the TAVIPILOT tele-operated robot used during transcatheter aortic valve …
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CLINICAL_TRIALS research · 2025-08-28Clinical Trial Update: CardioHeartConnect: Commercially Available Fitness for Cardiac Rehabilitation [NA]
The trial update indicates that CardioHeartConnect, a study on using commercially available fitness for cardiac rehabilitation, is currently…
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CLINICAL_TRIALS research · 2025-08-28Clinical Trial Update: Prospective, Multicenter, Randomized Controlled Clinical Study Evaluating the VitaFlow Liberty® Flex Transcatheter Aortic Valve Delivery System for the Treatment of Severe Aortic Stenosis Lesions [NA]
A multicenter randomized clinical study is evaluating the VitaFlow Liberty Flex transcatheter aortic valve delivery system for treating seve…
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CLINICAL_TRIALS research · 2025-08-28Clinical Trial Update: VRAP-Heart - Virtual Reality Assisted Patient Empowerment for Interventions in Structural Heart Disease [NA]
Clinical trial update for VRAP-Heart, a virtual reality assisted patient empowerment intervention for structural heart disease. The study is…
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CLINICAL_TRIALS research · 2025-08-22Clinical Trial Update: Antagonization of Heparin With Protamine Sulfate After TAVI [Phase 3]
A Phase 3 clinical trial is evaluating whether protamine sulfate can antagonize heparin after transcatheter aortic valve implantation, and t…
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CLINICAL_TRIALS research · 2025-08-22Clinical Trial Update: Assessment of Coronary Artery Disease Before Transcatheter Aortic Valve Replacement: A Randomized, Multicenter, Non-Inferiority Trial [NA]
This clinical trial update describes a randomized, multicenter, non-inferiority study evaluating assessment of coronary artery disease befor…
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CLINICAL_TRIALS research · 2025-08-19Clinical Trial Update: Evaluation of Safety and Effectiveness of the EMBLOK EPS Compared With No Cerebral Embolic Protection During TAVR [NA]
Clinical trial update assessing the safety and effectiveness of the EMBLOK Embolic Protection System during transcatheter aortic valve repla…
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CLINICAL_TRIALS research · 2025-08-15Clinical Trial Update: CT-evaluation of Coronary Ostia Height After Surgical Aortic Valve Replacement. [NA]
A clinical trial evaluating CT-based assessment of coronary ostia height after surgical aortic valve replacement is currently enrolling by i…
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CLINICAL_TRIALS research · 2025-08-14Clinical Trial Update: Clinical Investigation for the PoliaValve Aortic Heart Valve- India [NA]
Clinical trial update for PoliaValve Aortic Heart Valve in India. The trial is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-08-11Clinical Trial Update: Perceval Aortic Bioprostheses : Durability Study.
The durability study of the Perceval aortic bioprosthesis has completed, summarizing long-term outcomes for this device.
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CLINICAL_TRIALS trial_result · 2025-08-11Clinical Trial Update: Defining Exercise Hemodynamics and Function After Transcatheter Aortic Valve Replacement (DEFINE-TAVR) Study.
The DEFINE-TAVR trial, which investigates exercise hemodynamics and function after transcatheter aortic valve replacement, has completed.
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CLINICAL_TRIALS research · 2025-08-07Clinical Trial Update: A Prospective, Multicenter, Observational Study of the Safety and Efficacy of Emergency Transcatheter Aortic Valve Replacement in Patients With Severe Aortic Stenosis
A prospective multicenter observational study evaluating the safety and efficacy of emergency transcatheter aortic valve replacement in pati…
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CLINICAL_TRIALS research · 2025-08-07Clinical Trial Update: Quantification of Myocardial Fibrosis in Aortis Stenosis
An ongoing clinical trial is investigating quantification of myocardial fibrosis in patients with aortic valve stenosis and is currently enr…
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: Evaluation of Safety and Effectiveness of the EMBLOK EPS During TAVR [NA]
Clinical trial update on the safety and effectiveness evaluation of the EMBLOK EPS embolic protection system during transcatheter aortic val…