Aortic Valve Stenosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-08-06Clinical Trial Update: Perioperative Hemodynamic and Microcirculatory Physiological Study During TAVI
The trial NCT06154642 evaluating perioperative hemodynamic and microcirculatory physiology during transcatheter aortic valve implantation fo…
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CLINICAL_TRIALS trial_result · 2024-06-11Clinical Trial Update: BIOVALVE - I / II Clincial Investigation [NA]
This document reports a completed BIOVALVE I/II clinical investigation sponsored by Biotronik AG. The study evaluated valvular heart disease…
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CLINICAL_TRIALS trial_result · 2024-05-31Clinical Trial Update: Periprocedural Continuation Versus Interruption of Oral Anticoagulant Drugs During Transcatheter Aortic Valve Implantation (POPular PAUSE TAVI) [Phase 4]
Phase 4 POPular PAUSE TAVI trial update comparing continuation versus interruption of oral anticoagulant therapy around transcatheter aortic…
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CLINICAL_TRIALS trial_result · 2024-05-22Clinical Trial Update: WATCH-TAVR, WATCHMAN for Patients With Atrial Fibrillation Undergoing Transcatheter Aortic Valve Replacement [NA]
The WATCH-TAVR trial evaluating the WATCHMAN left atrial appendage closure device in patients with atrial fibrillation undergoing transcathe…
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CLINICAL_TRIALS trial_result · 2024-04-26Clinical Trial Update: Cerebrovascular EveNts in Patients Undergoing TranscathetER Aortic Valve Implantation With Balloon-expandable Valves Versus Self-expandable Valves.
A completed clinical trial evaluating cerebrovascular events in patients undergoing transcatheter aortic valve implantation with balloon-exp…
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CLINICAL_TRIALS trial_result · 2024-03-20Clinical Trial Update: PROACT Xa - A Trial to Determine if Participants With an On-X Aortic Valve Can be Maintained Safely on Apixaban [Phase 3]
Phase 3 trial PROACT Xa evaluating whether patients with On-X aortic valves can be safely maintained on apixaban; the study was terminated w…
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CLINICAL_TRIALS trial_result · 2024-01-10Clinical Trial Update: Medtronic Evolut™ EXPAND TAVR I Feasibility Study [NA]
Clinical feasibility study for Medtronic Evolut EXPAND TAVR I was terminated; results posted.
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CLINICAL_TRIALS trial_result · 2023-02-16Clinical Trial Update: Assessing the Incidence of Postoperative Delirium Following Aortic Valve Replacement
A completed clinical trial evaluating the incidence of postoperative delirium after aortic valve replacement.
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CLINICAL_TRIALS trial_result · 2022-12-27Clinical Trial Update: REPRISE IV: LOTUS Edge Valve System in Intermediate Surgical Risk Subjects [NA]
Clinical trial update for REPRISE IV evaluating the LOTUS Edge Valve System in intermediate surgical risk patients with aortic valve stenosi…
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CLINICAL_TRIALS trial_result · 2022-11-22Clinical Trial Update: JENAVALVE AS EFS TRIAL: Pericardial TAVR Aortic Stenosis Study [NA]
Clinical trial update for the JenaValve EFS trial in pericardial TAVR for aortic stenosis; status unknown with results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-07-27Clinical Trial Update: Rotterdam EDOXaban Leaflet Evaluation in Patients After Transcatheter Aortic Valve Implantation [Phase 3]
Phase 3 trial update evaluating edoxaban leaflet evaluation after transcatheter aortic valve implantation for patients with aortic valve ste…
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CLINICAL_TRIALS trial_result · 2022-04-04Clinical Trial Update: Impact of Local Tissue Inflammation on Intramyocardial Conduction Pathways Post Percutaneous Valve : Evaluation by Positron Emission Tomography on Exploratory Cohort [Phase 2]
Phase 2 exploratory trial evaluating how local tissue inflammation affects intramyocardial conduction after percutaneous valve intervention …
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CLINICAL_TRIALS trial_result · 2022-03-31Clinical Trial Update: Single Antiplatelet Treatment With Ticagrelor or Aspirin After Transcatheter Aortic Valve Implantation [Phase 4]
Phase 4 trial evaluating single antiplatelet therapy with ticagrelor or aspirin following transcatheter aortic valve implantation.
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CLINICAL_TRIALS trial_result · 2022-03-08Clinical Trial Update: Anticoagulation for Aortic Bioprosthesis (ANTIPRO) [Phase 4]
Phase 4 clinical trial update on anticoagulation for patients with aortic valve bioprostheses completed.
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CLINICAL_TRIALS trial_result · 2022-02-14Clinical Trial Update: Safety Profile Evaluation of TICagrelor Alone Compared to a Combination of Lysine Acetylsalicylate-Clopidogrel in the Context of Transcatheter Aortic Valve Implantation (TAVI) [Phase 3]
Phase 3 trial evaluating safety of ticagrelor alone versus a combination of lysine acetylsalicylate-clopidogrel in patients undergoing trans…
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CLINICAL_TRIALS trial_result · 2022-01-24Clinical Trial Update: 5 Year Observation of Patients With PORTICO Valves
This update presents five-year follow-up results from patients treated with the PORTICO transcatheter aortic valve for aortic valve stenosis…
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CLINICAL_TRIALS trial_result · 2021-11-08Clinical Trial Update: Anticoagulant Versus Dual Antiplatelet Therapy for Preventing Leaflet Thrombosis and Cerebral Embolization After Transcatheter Aortic Valve Replacement [Phase 4]
Phase 4 trial comparing an anticoagulant to dual antiplatelet therapy for preventing leaflet thrombosis and cerebral embolization after tran…
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CLINICAL_TRIALS trial_result · 2021-09-30Clinical Trial Update: ExCEED: CENTERA THV System in Intermediate Risk Patients Who Have Symptomatic, Severe, Calcific, Aortic Stenosis [NA]
The CENTERA Transcatheter Heart Valve System trial for intermediate-risk patients with symptomatic, severe calcific aortic stenosis is activ…
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CLINICAL_TRIALS trial_result · 2021-09-09Clinical Trial Update: Medtronic Evolut Transcatheter Aortic Valve Replacement in Low Risk Patients [NA]
Medtronic's Evolut Transcatheter Aortic Valve Replacement trial in low-risk patients with aortic valve stenosis has posted results. The stud…
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CLINICAL_TRIALS trial_result · 2021-07-21Clinical Trial Update: Home-Based Exercise Program For Recovery After Transcatheter Aortic Valve Replacement [NA]
Clinical trial completed studying a home-based exercise program for recovery after transcatheter aortic valve replacement, with results post…
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CLINICAL_TRIALS trial_result · 2021-04-20Clinical Trial Update: Preoperative Intravenous Ferric Carboxymaltose and Placebo in the Treatment of Patients Undergoing Cardiac Surgery [Phase 4]
Phase 4 trial investigating preoperative intravenous ferric carboxymaltose versus placebo in patients undergoing cardiac surgery.
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CLINICAL_TRIALS trial_result · 2021-03-03Clinical Trial Update: A Trial to Assess the Safety and Efficacy of Prophylactic TicagrelOr With Acetylsalicylic Acid Versus CLopidogrel With Acetylsalicylic Acid in the Development of Cerebrovascular EMbolic Events During TAVI [Phase 3]
A Phase 3 trial comparing prophylactic ticagrelor with aspirin versus clopidogrel with aspirin for reducing cerebrovascular embolic events d…
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CLINICAL_TRIALS trial_result · 2021-02-01Clinical Trial Update: Trifecta™ Long Term Follow-Up (LTFU) Study
The Trifecta long-term follow-up trial has completed with results posted in 2021. This update provides extended outcome data for the Abbott …
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CLINICAL_TRIALS trial_result · 2021-01-12Clinical Trial Update: Portico Re-sheathable Transcatheter Aortic Valve System US IDE Trial [NA]
Trial update for the Portico re-sheathable transcatheter aortic valve system US IDE trial; status is ACTIVE_NOT_RECRUITING with results post…
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CLINICAL_TRIALS trial_result · 2020-11-02Clinical Trial Update: PREVAIL-TF: Transfemoral Placement of Aortic Balloon Expandable Transcatheter Valves Trial (Europe) [NA]
Clinical trial update for PREVAIL-TF in Europe assessing transfemoral placement of aortic valve expandables; study completed with results po…