Aortic Valve Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-03-20Clinical Trial Update: PROACT Xa - A Trial to Determine if Participants With an On-X Aortic Valve Can be Maintained Safely on Apixaban [Phase 3]
Phase 3 trial PROACT Xa evaluating whether patients with On-X aortic valves can be safely maintained on apixaban; the study was terminated w…
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CLINICAL_TRIALS trial_result · 2024-01-31Clinical Trial Update: Del Nido Versus HTK Cardioplegia in Adult Aortic Valve Replacement [Phase 4]
A Phase 4 clinical trial comparing Del Nido versus HTK cardioplegia in adult aortic valve replacement is underway with unknown status.
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CLINICAL_TRIALS trial_result · 2023-11-22Clinical Trial Update: Trifecta™ Durability Study
Clinical trial update for the Trifecta Durability Study (NCT01256710) related to aortic valve disease; study status is terminated with resul…
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CLINICAL_TRIALS trial_result · 2023-10-23Clinical Trial Update: Antithrombotic Strategy Based on Clinical Events and 4D-CT for Patients After TAVR [Phase 4]
A Phase 4 clinical trial evaluating an antithrombotic strategy guided by clinical events and 4D-CT imaging after transcatheter aortic valve …
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CLINICAL_TRIALS trial_result · 2023-02-08Clinical Trial Update: Comparison of Two Pericardial Bioprostheses in AVR [NA]
Clinical trial comparing two pericardial bioprostheses for aortic valve replacement has completed with posted results.
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CLINICAL_TRIALS trial_result · 2022-07-27Clinical Trial Update: Perceval Sutureless Implant Versus Standard-Aortic Valve Replacement [NA]
A terminated clinical trial comparing Perceval sutureless aortic valve replacement with standard AVR; results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-03-08Clinical Trial Update: Anticoagulation for Aortic Bioprosthesis (ANTIPRO) [Phase 4]
Phase 4 clinical trial update on anticoagulation for patients with aortic valve bioprostheses completed.
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CLINICAL_TRIALS trial_result · 2022-02-21Clinical Trial Update: Ilioinguinal Nerve Block in Transcatheter Aortic Valve Implantation [Phase 4]
Phase 4 clinical trial investigating ilioinguinal nerve block in transcatheter aortic valve implantation for anesthesia management.
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CLINICAL_TRIALS trial_result · 2021-11-16Clinical Trial Update: Use of Transvenous Pacing Wire During Minimally Invasive Port Access Aortic Valve Surgery [NA]
Clinical trial update for use of a transvenous pacing wire during minimally invasive port access aortic valve surgery; study terminated and …
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CLINICAL_TRIALS trial_result · 2021-09-24Clinical Trial Update: Renin-angiotensin System Blockade Benefits in Clinical Evolution and Ventricular Remodeling After Transcatheter Aortic Valve Implantation (RASTAVI) [Phase 4]
Phase 4 clinical trial assessing the effects of renin-angiotensin system blockade on clinical evolution and ventricular remodeling after tra…
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CLINICAL_TRIALS trial_result · 2020-04-30Clinical Trial Update: Antiplatelet Therapy for Patients Undergoing Transcatheter Aortic Valve Implantation [Phase 4]
Phase 4 clinical trial update evaluating antiplatelet therapy in patients undergoing transcatheter aortic valve implantation (TAVI).
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CLINICAL_TRIALS trial_result · 2020-03-24Clinical Trial Update: Bioprosthetic or Native Aortic Scallop Intentional Laceration to Prevent Iatrogenic Coronary Artery Obstruction (BASILICA) Prospective Investigation [NA]
Prospective investigation of BASILICA procedure to prevent iatrogenic coronary obstruction during aortic valve interventions; study complete…
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CLINICAL_TRIALS trial_result · 2020-01-18Clinical Trial Update: Phase III Study Comparing Two Methods of Cardioplegia in Aortic Valve Surgery Custodiol-N Versus Custodiol [Phase 3]
Phase III study comparing two methods of cardioplegia in aortic valve surgery; study completed.
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CLINICAL_TRIALS research · 2020-01-18Clinical Trial Update: Assessment of Osteoblastic Activity With 18F-Fluoride in Aortic Bioprosthesis Structural Valve Dysfunction (SVD) [Phase 4]
A Phase 4 trial evaluating osteoblastic activity using 18F-Fluoride imaging in patients with structural valve dysfunction of aortic bioprost…
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CLINICAL_TRIALS trial_result · 2019-11-08Clinical Trial Update: EDWARDS INTUITY Elite Valve System
Clinical trial update for the Edwards INTUITY Elite Valve System showing completed status with results posted.
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CLINICAL_TRIALS trial_result · 2019-10-14Clinical Trial Update: EDWARDS INTUITY Valve System FOUNDATION Study
Clinical trial update for the Edwards INTUITY Valve System FOUNDATION study; completed with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-08-09Clinical Trial Update: Decalcification of the Aortic Valve by Vitamin K2 (Menaquinone-7) [Phase 2]
A Phase 2 trial investigating decalcification of the aortic valve using vitamin K2 (menaquinone-7). Status is currently unknown.
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CLINICAL_TRIALS trial_result · 2019-02-07Clinical Trial Update: PAR I - Patient-to-Annulus Relation I
Abbott Medical Devices reports completion of the PAR I trial evaluating patient-to-annulus relation in aortic valve disease.
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CLINICAL_TRIALS trial_result · 2019-01-28Clinical Trial Update: EDWARDS INTUITY Valve System CADENCE-MIS Study [NA]
The CADENCE-MIS study evaluating Edwards Lifesciences' INTUITY Valve System has completed, with results posted.
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CLINICAL_TRIALS trial_result · 2019-01-28Clinical Trial Update: The Del Nido Versus Cold Blood Cardioplegia in Aortic Valve Replacement [NA]
Completed clinical trial comparing Del Nido versus cold blood cardioplegia in aortic valve replacement; the study status indicates completio…
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CLINICAL_TRIALS trial_result · 2018-08-23Clinical Trial Update: The Effect of the Hyperinsulinemic Normoglycemic Clamp on Myocardial Function and Utilization of Glucose [NA]
Clinical trial completed evaluating the effect of the hyperinsulinemic normoglycemic clamp on myocardial function and glucose utilization in…
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CLINICAL_TRIALS trial_result · 2018-07-26Clinical Trial Update: 15 Years Outcomes Following Bioprosthetic vs Mechanical Aortic Valve Replacement Between 50-65 Years
A 15-year follow-up update comparing bioprosthetic versus mechanical aortic valve replacement in adults aged 50-65, based on completed clini…
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CLINICAL_TRIALS research · 2018-07-26Clinical Trial Update: TriRec - Trileaflet Reconstruction of the Aortic Valve With Autologous Pericardium [NA]
Clinical trial update for TriRec, a trileaflet reconstruction of the aortic valve using autologous pericardium. The study is currently recru…
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CLINICAL_TRIALS research · 2018-07-23Clinical Trial Update: SPAnish Aortic VALVE Multicentric Study
This document provides an update on the SPAnish Aortic VALVE Multicentric Study sponsored by a Spanish biomedical research foundation, with …
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CLINICAL_TRIALS trial_result · 2018-07-17Clinical Trial Update: Aspirin Versus Aspirin+Clopidogrel as Antithrombotic Treatment Following TAVI [Phase 4]
Phase 4 trial comparing aspirin alone to aspirin plus clopidogrel as antithrombotic therapy after transcatheter aortic valve implantation ha…