Anorexia
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Anamorelin Hydrochloride in Reducing Anorexia in Patients With Advanced Non-small Cell Lung Cancer [Phase 2, Phase 3]
This document reports an ongoing phase 2/3 clinical trial evaluating anamorelin hydrochloride to reduce anorexia in patients with advanced n…
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Effects of Mirtazapine on Appetite in Advanced Cancer Patients [Phase 2]
A Phase 2 clinical trial is evaluating the effect of mirtazapine on appetite in patients with advanced cancer, with the study currently acti…
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CLINICAL_TRIALS research · 2025-09-17Clinical Trial Update: The Effect of a Protective Oral Care Protocol Using Peppermint Oil Mouthwash [NA]
An update on a clinical trial evaluating a protective oral care protocol using peppermint oil mouthwash for patients with hematologic neopla…
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: A Prospective Multicentre Real-world Assessment of the Efficacy of Danning Tablets in Alleviating Digestive Symptoms
A prospective multicentre real-world study is evaluating the efficacy of Danning Tablets for digestive symptoms, with recruitment ongoing.
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CLINICAL_TRIALS trial_result · 2024-10-16Clinical Trial Update: Effectiveness of Bacillus Spore Probiotics in Reducing Constipation, Anorexia, and Slow Weight Gain in Children [NA]
This completed clinical trial update assesses the effectiveness of a Bacillus spore probiotic in reducing constipation, anorexia (loss of ap…
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CLINICAL_TRIALS other · 2024-10-03Clinical Trial Update: Olanzapine Anorexia Cachexia [Phase 3]
A completed Phase 3 clinical trial evaluating olanzapine for anorexia in cachexia. The update notes the study status but does not provide re…
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CLINICAL_TRIALS research · 2024-07-24Clinical Trial Update: Olanzapine for Cancer Related Anorexia-cachexia Syndrome [Phase 3]
Mahidol University is conducting a Phase 3 trial of olanzapine for cancer-related anorexia-cachexia syndrome, and the study is currently rec…
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CLINICAL_TRIALS trial_result · 2024-01-12Clinical Trial Update: Study to Compare the Effects of Repeated Doses of an Investigational New Drug and a Placebo on Appetite in Advanced Cancer and Anorexia [Phase 1]
Phase 1 study comparing repeated doses of an investigational drug versus placebo to assess effects on appetite in advanced cancer and anorex…
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CLINICAL_TRIALS trial_result · 2022-05-18Clinical Trial Update: Mirtazapine Versus Megestrol Acetate in Treatment of Anorexia-cachexia in Advanced Cancer Patients. [Phase 2]
Phase 2 trial comparing mirtazapine to megestrol acetate for anorexia in advanced cancer patients; current status is unknown.
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CLINICAL_TRIALS trial_result · 2021-09-09Clinical Trial Update: Megestrol to Limit Weight Loss and Improve Quality of Life in Treating Patients With Head and Neck Cancer [Phase 3]
Phase 3 trial evaluating megestrol to limit weight loss and improve quality of life in patients with head and neck cancer.
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CLINICAL_TRIALS trial_result · 2021-09-09Clinical Trial Update: Megestrol in Treating Patients Who Are Undergoing Radiation Therapy for Lung Cancer [Phase 3]
Phase 3 trial evaluating megestrol for anorexia/cachexia in patients undergoing radiation therapy for lung cancer has completed.
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CLINICAL_TRIALS trial_result · 2020-04-29Clinical Trial Update: Creatine in Treating Patients With Cancer-Associated Weight Loss [Phase 3]
Phase 3 trial investigating creatine for cancer-associated weight loss; study completed.
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EMA approval · 2017-11-30EMA Refused: Adlumiz (anamorelin hydrochloride) — Helsinn Birex Pharmaceuticals Ltd.
EMA refused Adlumiz (anamorelin hydrochloride) from Helsinn Birex Pharmaceuticals Ltd., a decision affecting its use for cachexia/anorexia i…
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CLINICAL_TRIALS trial_result · 2017-06-20Clinical Trial Update: Encapsulated Nutrients' Acute Effects on Appetite; ENcapsulated, lipiD, aminO, pRobiotic, SatiEty [NA]
A completed clinical trial sponsored by Arne Astrup evaluated the acute effects of encapsulated nutrients on appetite, investigating a formu…
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CLINICAL_TRIALS trial_result · 2016-07-14Clinical Trial Update: Comparison of Megestrol and/or Omega-3 Fatty Acid-Enriched Nutritional Supplement in Treating Patients With Cancer-Related Weight Loss and Lack of Appetite [Phase 3]
Phase 3 trial evaluating megestrol acetate and an omega-3 fatty acid-enriched nutritional supplement for cancer-related weight loss and anor…
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CLINICAL_TRIALS trial_result · 2016-04-20Clinical Trial Update: Evaluate Weight Gain Using 2 Different Formulations of Megestrol Acetate Oral Suspension for AIDS-related Weight Loss [Phase 2]
Phase 2 trial evaluating two formulations of megestrol acetate oral suspension for AIDS-related weight loss completed; results posted in 201…
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CLINICAL_TRIALS withdrawal · 2016-01-12Clinical Trial Update: Nicotine in Treating "Hunger Pain" in Patients With Malignant Bowel Obstruction Caused By Cancer [NA]
A Mayo Clinic trial evaluating nicotine to treat hunger pain in patients with malignant bowel obstruction due to cancer has been withdrawn.
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CLINICAL_TRIALS research · 2015-12-04Clinical Trial Update: The Safety and Effect Study of Acupuncture for Anorexia in Patients With Gastrointestinal Tract and Lung Cancers [Phase 2, Phase 3]
A clinical trial update describing the safety and efficacy study of acupuncture for anorexia in patients with gastrointestinal tract and lun…
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CLINICAL_TRIALS withdrawal · 2014-02-03Clinical Trial Update: Megestrol Acetate With or Without Mirtazapine in Treating Cancer Patients With Weight Loss or Loss of Appetite [Phase 2]
Phase 2 clinical trial of megestrol acetate with or without mirtazapine for cancer patients with weight loss or loss of appetite has been wi…
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CLINICAL_TRIALS trial_result · 2013-05-24Clinical Trial Update: Megestrol Acetate in Treating Weight Loss or Anorexia in Young Patients With Malignancies Who Are Undergoing Radiation Therapy and/or Chemotherapy [Phase 2]
Phase 2 clinical trial of megestrol acetate for weight loss or anorexia in children undergoing cancer treatment was terminated with results …
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CLINICAL_TRIALS trial_result · 2011-07-01Clinical Trial Update: Energy Dense Formula to People Living in Old Peoples Home [NA]
A completed clinical trial evaluated an energy-dense formula for residents of an elderly care home to address protein-energy malnutrition an…
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CLINICAL_TRIALS trial_result · 2011-05-05Clinical Trial Update: Etanercept in Treating Cancer-Related Cachexia and Anorexia in Patients With Advanced Cancer [Phase 3]
Phase 3 trial evaluating etanercept for cancer-related cachexia and anorexia in advanced cancer has completed.
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CLINICAL_TRIALS research · 2011-02-14Clinical Trial Update: Study to Evaluate the Efficacy and Tolerability of Apevinat BC Compared to Vitamin Complex [Phase 3]
A Phase 3 clinical trial is evaluating the efficacy and tolerability of Apevinat BC compared with a Vitamin Complex for lack of appetite/ano…
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CLINICAL_TRIALS trial_result · 2010-02-09Clinical Trial Update: Orexigenic Therapy With Delta-9-tetrahydrocannabinol in Advanced Cancer Patients With Chemosensory Abnormalities - a Pilot Study [Phase 2]
This phase 2 pilot study evaluates delta-9-tetrahydrocannabinol (Dronabinol) as an orexigenic therapy to improve appetite in advanced cancer…
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CLINICAL_TRIALS trial_result · 2008-07-22Clinical Trial Update: Safety and Efficacy Study of Betamarc to Treat Loss of Weight and Appetite in Non-Small Cell Lung Cancer [Phase 2]
Phase 2 trial evaluating Betamarc for loss of weight and appetite in non-small cell lung cancer; the study was terminated.