Alzheimer Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-01-02Clinical Trial Update: Non-pharmacological Care of Alzheimer's Disease: Benefice of Musical Interventions [NA]
This completed clinical trial assesses the benefits of musical interventions as non-pharmacological care for Alzheimer's disease.
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CLINICAL_TRIALS trial_result · 2016-12-30Clinical Trial Update: Evaluation of E2609 in Subjects With Mild Cognitive Impairment or Mild Dementia Due to Alzheimer's Disease (Study: E2609-A001-101 Amendment 02) [Phase 1]
This clinical trial update reports the completion of a Phase 1 study (E2609-A001-101 Amendment 02) evaluating the drug E2609 in subjects wit…
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CLINICAL_TRIALS trial_result · 2016-12-28Clinical Trial Update: A Multi-national Study to Identify Treatment Discontinuation Rate in de Novo Alzheimer's Disease Patients Who Have Been Newly Prescribed With Donepezil (Aricept) in Asia (ADOS)
A multinational observational study completed in Asia examining how often patients with de novo Alzheimer's disease discontinue donepezil (A…
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CLINICAL_TRIALS trial_result · 2016-12-16Clinical Trial Update: Efficacy and Safety of MNI-672 SPECT for Detection/Exclusion of Cerebral B-amyloid in AD Subjects Compared to HVs. [Phase 1]
A Phase 1 clinical trial evaluated the efficacy and safety of the MNI-672 SPECT imaging agent for detecting cerebral beta-amyloid in Alzheim…
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CLINICAL_TRIALS research · 2016-12-16Clinical Trial Update: Evaluation of [18F]MNI-777 PET as a Marker of Tau Pathology in Subjects With Tauopathies Compared to Healthy Subjects [Phase 1]
Phase 1 study evaluating the PET tracer [18F]MNI-777 as a marker of tau pathology in tauopathy subjects and healthy controls has been comple…
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CLINICAL_TRIALS trial_result · 2016-12-16Clinical Trial Update: Evaluation of [18F]MNI-815 as a Potential PET Radioligand for Imaging Tau Protein in the Brain of Patients With Tauopathies [EARLY_Phase 1]
Early Phase 1 study evaluating the PET radioligand [18F]MNI-815 for imaging tau in tauopathies has been completed, involving Alzheimer's dis…
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CLINICAL_TRIALS research · 2016-12-13Clinical Trial Update: Neurofeedback as a Novel Treatment for Mild Cognitive Impairment & Early Alzheimer's Disease [NA]
Clinical trial update exploring neurofeedback as a potential treatment for Mild Cognitive Impairment and early Alzheimer's disease; current …
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CLINICAL_TRIALS withdrawal · 2016-12-13Clinical Trial Update: Study to Determine the Effect of Itraconazole on the Pharmacokinetics of Rilapladib (SB659032) in Healthy Volunteers [Phase 1]
A Phase 1 study investigating the pharmacokinetic interaction between itraconazole and rilapladib in healthy volunteers has been withdrawn.
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CLINICAL_TRIALS trial_result · 2016-12-12Clinical Trial Update: Tai Chi 6-Form Sports Apparatus With Alzheimer's Disease [NA]
This ClinicalTrials.gov study evaluating a Tai Chi 6-Form Sports Apparatus for Alzheimer's disease has completed.
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CLINICAL_TRIALS trial_result · 2016-12-07Clinical Trial Update: A Single Dose Study of KHK6640 in Japanese Patients With Alzheimer's Disease. [Phase 1]
Notes the completion of a Phase 1 single-dose study of KHK6640 in Japanese patients with Alzheimer's disease.
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CLINICAL_TRIALS trial_result · 2016-12-05Clinical Trial Update: A Study of the Safety and Tolerability of AZD5213 Effect on Sleep for Patients With Alzheimer's/Cognitive Impairment [Phase 2]
A Phase 2 trial evaluating the safety and tolerability of AZD5213 on sleep in patients with mild cognitive impairment or mild Alzheimer's di…
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FDA approval · 2016-11-21FDA Approved: VIZAMYL — Supplemental Application (GE Healthcare Inc. (Medi-Physics, Inc. dba GE Healthcare))
FDA approved a supplemental application for VIZAMYL (Flutemetamol F-18) from GE Healthcare, updating its regulatory status for this imaging …
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CLINICAL_TRIALS trial_result · 2016-11-21Clinical Trial Update: Mass Practice of Activities of Daily Living in Dementia (STOMP) [NA]
The STOMP trial, studying mass practice of activities of daily living in dementia, has completed.
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CLINICAL_TRIALS trial_result · 2016-11-18Clinical Trial Update: Efficacy, Safety and Tolerability of Rivastigmine Patch in Patients With Mild to Moderate Alzheimer's Disease Switched From Cholinesterase Inhibitors [Phase 4]
Phase 4 trial update evaluating the efficacy, safety, and tolerability of rivastigmine patch in mild-to-moderate Alzheimer's disease patient…
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FDA approval · 2016-11-17FDA Approved: DONEPEZIL HYDROCHLORIDE — Supplemental Application (Dr. Reddys Laboratories Limited)
FDA approved a supplemental application for a generic donepezil hydrochloride tablet from Dr. Reddy's Laboratories Limited, confirming regul…
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CLINICAL_TRIALS trial_result · 2016-11-10Clinical Trial Update: The Cognitive Effects of Lorazepam in Healthy Older Individuals With TOMM40 Variable-length Polymorphisms [Phase 1]
Phase 1 clinical trial from Mayo Clinic evaluating the cognitive effects of lorazepam in healthy older adults with TOMM40 polymorphisms, in …
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CLINICAL_TRIALS trial_result · 2016-11-10Clinical Trial Update: Tolerability of Rivastigmine Before and After Switching From Oral Formulation to Transdermal Patch in Alzheimer's Dementia [Phase 4]
Phase 4 trial evaluating tolerability of rivastigmine when switching from the oral formulation to a transdermal patch in Alzheimer's disease…
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FDA approval · 2016-11-10FDA Approved: DONEPEZIL HYDROCHLORIDE — Original Application (Unichem Pharmaceuticals (USA), Inc.)
The FDA approved an Original Application for a generic donepezil hydrochloride product by Unichem Pharmaceuticals (USA), Inc., expanding acc…
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FDA approval · 2016-11-08FDA Approved: DONEPEZIL HYDROCHLORIDE — Supplemental Application (Macleods Pharmaceuticals Limited)
FDA approved a supplemental application for donepezil hydrochloride by Macleods Pharmaceuticals Limited.
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FDA approval · 2016-11-08FDA Approved: DONEPEZIL HYDROCHLORIDE — Supplemental Application (Macleods Pharmaceuticals Limited)
FDA approved a supplemental application for donepezil hydrochloride by Macleods Pharmaceuticals Limited. The approval covers changes request…
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FDA approval · 2016-11-08FDA Approved: DONEPEZIL HYDROCHLORIDE — Supplemental Application (Macleods Pharmaceuticals Limited)
The FDA approved a supplemental application for donepezil hydrochloride from Macleods Pharmaceuticals Limited.
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CLINICAL_TRIALS trial_result · 2016-11-07Clinical Trial Update: Mild Alzheimer''s Disease to Assess the of Extended Release Formulation of Rosiglitazone (RSG XR) [Phase 1]
A Phase 1 clinical trial evaluating an extended-release formulation of rosiglitazone (RSG XR) in mild Alzheimer's disease has completed.
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CLINICAL_TRIALS research · 2016-11-04Clinical Trial Update: Establishment of a Bank of Biospecimens for Future Research on Age-related Cognitive Disorders
This completed study established a centralized bank of biospecimens to support future research on age-related cognitive disorders, including…
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CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: A Study of RO5313534 as Add-on to Donepezil Treatment in Patients With Mild to Moderate Alzheimer's Disease [Phase 2]
A Phase 2 study evaluated RO5313534 as an add-on to donepezil in patients with mild to moderate Alzheimer's disease; the trial has completed…
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CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: A Multiple Ascending Dose Study of R1450 in Patients With Alzheimer Disease. [Phase 1]
Phase 1 multiple ascending dose study of R1450 in patients with Alzheimer's disease has completed. The trial evaluated safety, tolerability,…