Alzheimer Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-03-12Clinical Trial Update: The Effectiveness And Safety Of Donepezil Hydrochloride (E2020) In Subjects With Mild To Severe Alzheimer's Disease Residing In An Assisted Living Facility [Phase 4]
Phase 4 trial evaluating the effectiveness and safety of donepezil hydrochloride (E2020) in adults with mild to severe Alzheimer's disease r…
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CLINICAL_TRIALS research · 2018-03-08Clinical Trial Update: The Effects of Acupuncture on the Risk of AD After TBI [NA]
This clinical trial update discusses a study evaluating whether acupuncture can affect the risk of Alzheimer's disease following traumatic b…
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FDA approval · 2018-03-06FDA Approved: MEMANTINE HYDROCHLORIDE — Supplemental Application (Macleods Pharmaceuticals Limited)
The FDA approved a supplemental application for Memantine hydrochloride (Macleods Pharmaceuticals Limited).
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CLINICAL_TRIALS trial_result · 2018-03-02Clinical Trial Update: Behavioral Expressions in Alzheimer's Disease
A University of Florida–sponsored clinical trial investigating behavioral expressions in Alzheimer's disease has completed.
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EMA guidance · 2018-02-28Revised guideline on clinical studies for Alzheimer's disease medicines
EU EMA releases a revised guideline outlining expectations for clinical studies assessing Alzheimer's disease medicines, including design, e…
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CLINICAL_TRIALS trial_result · 2018-02-22Clinical Trial Update: A Pilot Clinical Trial of Exendin-4 in Alzheimer's Disease [Phase 2]
Phase 2 pilot trial of Exendin-4 in Alzheimer's disease and mild cognitive impairment was terminated.
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CLINICAL_TRIALS trial_result · 2018-02-20Clinical Trial Update: Idalopirdine in Patients With Mild-moderate Alzheimer's Disease Treated With Donepezil [Phase 3]
A Phase 3 trial evaluating idalopirdine in patients with mild-to-moderate Alzheimer's disease already treated with donepezil has completed; …
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CLINICAL_TRIALS trial_result · 2018-02-15Clinical Trial Update: Efficacy of ORM-12741 on Agitation/Aggression Symptoms in Alzheimer's Disease [Phase 2]
Phase 2 trial evaluating ORM-12741 for agitation/aggression in Alzheimer's disease has completed.
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CLINICAL_TRIALS trial_result · 2018-02-12Clinical Trial Update: Study of SB-742457 or Donepezil Versus Placebo in Subjects With Mild-to-moderate Alzheimer's Disease [Phase 2]
Phase 2 study comparing SB-742457 or donepezil against placebo in mild-to-moderate Alzheimer's disease; results were posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-02-12Clinical Trial Update: The Effect of rTMS Treatment on Alzheimer's and Sleep Quality [NA]
A completed clinical trial evaluating the effect of repetitive transcranial magnetic stimulation (rTMS) on Alzheimer's disease and sleep qua…
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FDA approval · 2018-02-09FDA Approved: MEMANTINE — Original Application (Apotex Corp.)
FDA approved Apotex Corp.'s original application for memantine hydrochloride, a generic memantine, for the treatment of Alzheimer's disease.
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CLINICAL_TRIALS trial_result · 2018-02-07Clinical Trial Update: Study of Idalopirdine in Patients With Mild - Moderate Alzheimer's Disease Treated With an Acetylcholinesterase Inhibitor [Phase 3]
Phase 3 trial investigating idalopirdine in mild-to-moderate Alzheimer's disease patients already on acetylcholinesterase inhibitors; study …
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CLINICAL_TRIALS trial_result · 2018-02-07Clinical Trial Update: Efficacy and Safety of MK-7622 as Adjunct Therapy in Participants With Alzheimer's Disease (MK-7622-012) [Phase 2]
Phase 2 trial evaluating MK-7622 as adjunct therapy in Alzheimer's disease was terminated with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-02-06Clinical Trial Update: Trial of Carvedilol in Alzheimer's Disease [Phase 4]
Phase 4 clinical trial of carvedilol in Alzheimer's disease has completed with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-02-05Clinical Trial Update: Alzheimer's Disease Acitretin Medication [Phase 2]
Phase 2 clinical trial of acitretin for Alzheimer disease completed; results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-02-01Clinical Trial Update: Study of Nasal Insulin to Fight Forgetfulness - Long-acting Insulin Detemir - 120 Days (SL120) [Phase 2]
Phase 2 study evaluating long-acting nasal insulin detemir for cognitive decline in Alzheimer’s disease and mild cognitive impairment has co…
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CLINICAL_TRIALS trial_result · 2018-01-31Clinical Trial Update: Venlafaxine for Depression in Alzheimer's Disease (DIADs-3) [NA]
Clinical trial update for venlafaxine in Alzheimer's disease with comorbid depression; study completed and results posted.
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CLINICAL_TRIALS trial_result · 2018-01-25Clinical Trial Update: Deep Transcranial Magnetic Stimulation for Treatment of Alzheimer's Disease [Phase 2]
Phase 2 clinical trial of deep transcranial magnetic stimulation for Alzheimer's disease has completed.
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CLINICAL_TRIALS trial_result · 2018-01-24Clinical Trial Update: DAOIB for the Treatment of Cognitive Function and Behavioral and Psychological Symptoms of Dementia [Phase 2]
Phase 2 clinical trial update for DAOIB addressing cognitive function and behavioral and psychological symptoms in dementia, completed.
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CLINICAL_TRIALS trial_result · 2018-01-11Clinical Trial Update: Practice Effects and Amyloid Imaging Using 18F-PIB or Flutemetamol PET and FDG-PET [Phase 2]
Phase 2 clinical trial evaluating practice effects and amyloid imaging using 18F-PIB or Flutemetamol PET and FDG-PET in Alzheimer's disease …
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FDA approval · 2017-12-27FDA Approved: GALANTAMINE — Supplemental Application (Slate Run Pharmaceuticals, LLC)
FDA approved a supplemental application for galantamine from Slate Run Pharmaceuticals, LLC.
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FDA approval · 2017-12-14FDA Approved: GALANTAMINE — Supplemental Application (Aurobindo Pharma Limited)
FDA approved a supplemental application for Galantamine from Aurobindo Pharma Limited, authorizing the generic version for use in mild to mo…
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CLINICAL_TRIALS trial_result · 2017-12-12Clinical Trial Update: Disrupted Sleep, Neuroendocrine Status and the Behavioral Symptoms of AD [NA]
Johns Hopkins University completed a clinical trial investigating disrupted sleep, neuroendocrine status, and behavioral symptoms in Alzheim…
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CLINICAL_TRIALS trial_result · 2017-12-07Clinical Trial Update: A Study of SB-742457, Added to Donepezil for the Treatment of Mild-to-moderate Alzheimer's Disease [Phase 2]
A Phase 2 trial evaluated SB-742457 added to donepezil for mild-to-moderate Alzheimer's disease. The study is completed and results were pos…
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CLINICAL_TRIALS trial_result · 2017-12-07Clinical Trial Update: LESCOD: "Lewy Body Screening in Cognitive Disorders" [NA]
The LESCOD study on Lewy body screening in cognitive disorders (NCT02263287) sponsored by Nantes University Hospital has been terminated.