Alzheimer Disease
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CLINICAL_TRIALS trial_result · 2025-02-04Clinical Trial Update: Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia: A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation [Phase 2, Phase 3]
The Dominantly Inherited Alzheimer Network Trial, studying potential disease-modifying treatments for individuals at risk for or with famili…
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CLINICAL_TRIALS trial_result · 2025-02-04Clinical Trial Update: STAR Caregivers - Virtual Training and Follow-up [NA]
Results from the STAR Caregivers virtual training and follow-up trial in Alzheimer's disease and dementia have been completed with results p…
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CLINICAL_TRIALS trial_result · 2025-02-03Clinical Trial Update: Safety and Immunogenicity of Repeated Doses of ABvac40 in Patients With a-MCI or Vm-AD [Phase 2]
Phase 2 study evaluating the safety and immunogenicity of repeated doses of ABvac40 in adults with Mild Cognitive Impairment or Alzheimer Di…
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CLINICAL_TRIALS trial_result · 2025-01-31Clinical Trial Update: A Study on the Safety, Tolerability and Immunogenicity of ALZ-101 in Participants With Early Alzheimer's Disease [Phase 1]
Alzinova's ALZ-101 Phase 1 trial in early Alzheimer's disease completed, assessing safety, tolerability, and immunogenicity. The study provi…
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CLINICAL_TRIALS research · 2025-01-31Clinical Trial Update: Escitalopram for Agitation in Alzheimer's Disease [Phase 3]
Phase 3 trial evaluating escitalopram for agitation in Alzheimer's disease is ongoing. The study status is ACTIVE_NOT_RECRUITING.
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CLINICAL_TRIALS research · 2025-01-30Clinical Trial Update: Preventing Medication Mismanagement in People Living with Dementia Through Automated Medication Dispensing with Facial Recognition and Video Observation [Phase 2]
Phase 2 trial evaluating automated medication dispensing with facial recognition and video observation to prevent medication mismanagement i…
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CLINICAL_TRIALS trial_result · 2025-01-27Clinical Trial Update: Effect of Food and Age on the Pharmacokinetics of LY03017 [Phase 1]
This update describes a Phase 1 pharmacokinetic study of LY03017 evaluating the effects of food and age on its pharmacokinetics.
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CLINICAL_TRIALS research · 2025-01-27Clinical Trial Update: Mindfulness for Cognition in Early-stage Alzheimer's Disease [NA]
The VA Boston Healthcare System is recruiting for a study to assess mindfulness-based approaches to support cognition in individuals with mi…
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CLINICAL_TRIALS research · 2025-01-27Clinical Trial Update: Hormone Replacement Trial Against ALzheimers' Disease [NA]
A clinical trial update indicates a hormone replacement therapy study for Alzheimer's disease is currently recruiting. The study is sponsore…
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CLINICAL_TRIALS withdrawal · 2025-01-27Clinical Trial Update: Investigating Brain Insulin Resistance in Alzheimer Disease with IntraNasal Insulin : a Multimodal Neuroimaging Study [NA]
A clinical trial investigating brain insulin resistance in Alzheimer’s disease and mild cognitive impairment using intranasal insulin; the s…
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FDA approval · 2025-01-24FDA Approved: LEQEMBI — Supplemental Application (Eisai Inc.)
FDA approves a supplemental application for LEQEMBI (lecanemab) submitted by Eisai Inc., resulting in labeling changes.
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CLINICAL_TRIALS research · 2025-01-24Clinical Trial Update: A Clinical Study to Evaluate the Long-Term Safety Sodium Oligomannate Capsules (GV-971) [Phase 4]
This document provides an update on the Phase 4 long-term safety study of Sodium oligomannate capsules (GV-971) for Alzheimer's disease, not…
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CLINICAL_TRIALS trial_result · 2025-01-23Clinical Trial Update: A Study of CST-2032 and CST-107 in Subjects With Mild Cognitive Impairment or Mild Dementia Due to Parkinson's or Alzheimer's Disease [Phase 2]
Phase 2 clinical trial update reporting results for CST-2032 and CST-107 in individuals with mild cognitive impairment or mild dementia due …
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CLINICAL_TRIALS trial_result · 2025-01-23Clinical Trial Update: Dynamic Response to Probiotics in Context of Alzheimer Disease: a Proof-of-concept Study [NA]
Completed proof-of-concept trial evaluating the impact of probiotics on outcomes in Alzheimer’s disease.
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CLINICAL_TRIALS trial_result · 2025-01-23Clinical Trial Update: Clinical and Genetic Study of Neurodegenerative Disorders With Cognitive Impairment
Completed clinical and genetic study of neurodegenerative disorders with cognitive impairment, highlighting Alzheimer's disease and dementia…
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CLINICAL_TRIALS research · 2025-01-23Clinical Trial Update: Investigation of AlzHeimer's Predictors in Subjective Memory Complainers - Extension Study [NA]
An extension study is investigating predictors of Alzheimer's disease in individuals with subjective memory complaints; recruitment is ongoi…
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CLINICAL_TRIALS trial_result · 2025-01-23Clinical Trial Update: A Double-Blind, Placebo-Controlled, Dose Ranging Study of Xanamem® in Healthy Elderly Volunteers [Phase 1, Phase 2]
Actinogen Medical completed a Phase 1/2 double-blind, placebo-controlled, dose-ranging trial of Xanamem in healthy elderly volunteers, with …
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FDA approval · 2025-01-22FDA Approved: RIVASTIGMINE — Supplemental Application (Mylan Pharmaceuticals Inc.)
FDA approved a supplemental application for rivastigmine by Mylan Pharmaceuticals Inc. The approval indicates a modification to the product'…
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FDA approval · 2025-01-22FDA Approved: RIVASTIGMINE — Supplemental Application (Amneal Pharmaceuticals LLC)
FDA approved a supplemental application for rivastigmine from Amneal Pharmaceuticals LLC.
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CLINICAL_TRIALS research · 2025-01-22Clinical Trial Update: A Phase 3 Study of Rotigotine in Combination with Rivastigmine in Mild to Moderate Alzheimer's Disease [Phase 3]
A Phase 3 trial evaluating rotigotine in combination with rivastigmine for mild-to-moderate Alzheimer's disease is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-01-17Clinical Trial Update: Clinical Safety and Efficacy Evaluation of NanoLithium® NP03 in Patients With Mild-to-severe Alzheimer's Disease [Phase 2]
Phase 2 clinical trial evaluating the safety and efficacy of NanoLithium NP03 in patients with mild-to-severe Alzheimer's disease has comple…
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CLINICAL_TRIALS research · 2025-01-17Clinical Trial Update: Evaluation of the Effects of Serious Cognitive Games on a Digital Tactile Table for Elderly People with Alzheimer's Disease or Related Disorders [NA]
An ongoing clinical trial is evaluating the effects of serious cognitive games delivered through a digital tactile table for elderly people …
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CLINICAL_TRIALS research · 2025-01-16Clinical Trial Update: Deep Cervical Lymphatlc-Venous Anastomosis Surgery for the Treatment of Alzheimer's Disease: A Pilot Study (DIVA Study) [Phase 3]
A Phase 3 clinical trial is recruiting to evaluate deep cervical lymphatic-venous anastomosis as a treatment for Alzheimer's disease (DIVA S…
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CLINICAL_TRIALS trial_result · 2025-01-16Clinical Trial Update: Targeting Default Mode Network Dysfunction in Persons At Risk of Alzheimer's Disease with Non-invasive Techniques [NA]
A completed clinical trial evaluating non-invasive methods to target default mode network dysfunction in people at risk for Alzheimer's dise…
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CLINICAL_TRIALS research · 2025-01-16Clinical Trial Update: Making Connections Thru Music [NA]
A clinical trial update from clinicaltrials.gov shows a Hopeful Aging-sponsored study exploring a music-based intervention for dementia-rela…