Alzheimer Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-04-30Clinical Trial Update: Effect of Physiologic Insulin Administration on Cognition [NA]
The update reports results from a trial evaluating physiologic insulin administration and its effects on cognition in Alzheimer disease.
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CLINICAL_TRIALS trial_result · 2025-04-30Clinical Trial Update: Early-onset Alzheimer's Disease Phenotypes: Neuropsychology and Neural Networks
Completed clinical trial from UCLA investigating early-onset Alzheimer's disease phenotypes with a focus on neuropsychology and neural netwo…
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CLINICAL_TRIALS trial_result · 2025-04-29Clinical Trial Update: A Dose-ranging Study to Investigate Efficacy of Buntanetap in Mild to Moderate AD [Phase 2, Phase 3]
A dose-ranging study evaluating the efficacy of Buntanetap in mild-to-moderate Alzheimer's disease (Phase 2/3) has completed with results po…
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CLINICAL_TRIALS trial_result · 2025-04-29Clinical Trial Update: A Safety and Tolerability Study of JNJ-54861911 in Participants With Early Alzheimer's Disease [Phase 2]
A Phase 2 safety and tolerability study of the investigational compound JNJ-54861911 in participants with early Alzheimer’s disease has comp…
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CLINICAL_TRIALS trial_result · 2025-04-29Clinical Trial Update: All About Me: An Intervention to Ease the Transition to Long Term Care [NA]
This trial update notes the completed status of Hopeful Aging's 'All About Me' intervention to ease the transition to long-term care for peo…
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CLINICAL_TRIALS trial_result · 2025-04-29Clinical Trial Update: Epigenetic Biomarkers for Alzheimer's Disease
Clinical trial update from the Chinese University of Hong Kong reporting on epigenetic biomarkers in Alzheimer's disease with the study stat…
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CLINICAL_TRIALS research · 2025-04-29Clinical Trial Update: Lack of Decision-making in Patients With Alzheimer's Disease : Functions Involved and the Daily Consequences [NA]
A clinical study investigating lack of decision-making in Alzheimer's disease, focusing on the functions involved and the daily consequences…
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CLINICAL_TRIALS trial_result · 2025-04-27Clinical Trial Update: A Study to Investigate Safety and Tolerability, Pharmacokinetics and Pharmacodynamics of JNJ-63733657 in Healthy Subjects and Subjects With Alzheimer's Disease [Phase 1]
A Phase 1 study evaluating safety, tolerability, pharmacokinetics, and pharmacodynamics of JNJ-63733657 in healthy subjects and individuals …
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CLINICAL_TRIALS trial_result · 2025-04-27Clinical Trial Update: Characterization of T-Cell Response in Participants Previously Treated With JNJ-54861911 (Atabecestat) [EARLY_Phase 1]
This early Phase 1 trial update describes characterization of T-cell responses in participants previously treated with atabecestat (JNJ-5486…
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CLINICAL_TRIALS trial_result · 2025-04-27Clinical Trial Update: A Study of Comparing Rates of Dementia and Alzheimer's Disease in Participants Initiating Methotrexate Versus Those Initiating Anti-tumor Necrosis Factor (TNF)-Alpha Therapy
A completed clinical trial comparing dementia and Alzheimer's disease incidence in participants initiating methotrexate versus those startin…
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CLINICAL_TRIALS trial_result · 2025-04-27Clinical Trial Update: A Study to Investigate the Regional Brain Kinetics of Brain Drug Transporters Using P-glycoprotein and Breast Cancer Resistance Protein Substrates and by Using the Positron Emission Tomography Ligand 11C-JNJ-63779586 in the Human Brain [Phase 1]
This Clinical Trial Update reports a Phase 1 study by Janssen Research & Development to investigate regional brain kinetics of P-glycoprotei…
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CLINICAL_TRIALS trial_result · 2025-04-27Clinical Trial Update: Alzheimer's Disease Stem Cells Multiple Infusions [Phase 1]
A Phase 1 study evaluating multiple infusions of stem cells for Alzheimer's disease has completed.
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CLINICAL_TRIALS withdrawal · 2025-04-27Clinical Trial Update: Histidine Oral Supplementation as a Therapeutic Modality for Alzheimer's Disease [Phase 4]
Phase 4 trial evaluating histidine oral supplementation for Alzheimer's disease has been withdrawn; no results are reported.
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CLINICAL_TRIALS trial_result · 2025-04-27Clinical Trial Update: The Swedish BioFINDER Study
Sweden's BioFINDER study (NCT01208675) has completed its clinical trial, evaluating mild cognitive impairment, Alzheimer's disease, dementia…
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CLINICAL_TRIALS research · 2025-04-27Clinical Trial Update: Evaluation of Tau Protein in the Brain of Participants With Alzheimer's Disease Compared to Healthy Participants [EARLY_Phase 1]
Early-phase clinical trial evaluating tau protein levels in the brains of participants with Alzheimer disease compared to healthy participan…
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FDA approval · 2025-04-25FDA Approved: MEMANTINE HYDROCHLORIDE — Supplemental Application (Amneal Pharmaceuticals LLC)
FDA approved a supplemental application for memantine hydrochloride (generic) by Amneal Pharmaceuticals LLC.
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CLINICAL_TRIALS research · 2025-04-25Clinical Trial Update: A Study of Remternetug (LY3372993) in Participants With Alzheimer's Disease (TRAILRUNNER-ALZ 1) [Phase 3]
A Phase 3 study of Remternetug (LY3372993) in participants with Alzheimer's disease is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-04-25Clinical Trial Update: Cognitive Health in Ageing Register: Investigational, Observational and Trial Studies in Dementia Research: Prospective Readiness Cohort Study
Janssen-sponsored prospective readiness cohort under the Cognitive Health in Ageing Register in Dementia Research investigates investigation…
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CLINICAL_TRIALS withdrawal · 2025-04-25Clinical Trial Update: Multiple Dose Trial of MK-4334 in Participants With Alzheimer's Clinical Syndrome (MK-4334-005) [Phase 1]
A Phase 1 multiple-dose trial of MK-4334 in participants with Alzheimer's disease and mild cognitive impairment has been withdrawn.
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CLINICAL_TRIALS research · 2025-04-24Clinical Trial Update: Discovery and Validation of Genetic Variants Affecting Microglial Activation in Alzheimer's Disease [Phase 2]
Phase 2 clinical trial exploring genetic variants that influence microglial activation in Alzheimer's disease; currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-04-23Clinical Trial Update: A Study to Verify the Clinical Benefit of Aducanumab in Participants With Early Alzheimer's Disease [Phase 3]
A Phase 3 trial evaluating aducanumab in early Alzheimer's disease was terminated and results were posted on 2025-04-23.
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CLINICAL_TRIALS trial_result · 2025-04-23Clinical Trial Update: ASURE: Alzheimer Study Using oRal Edaravone [Phase 2]
This document reports the completion of a Phase 2 trial (ASURE) evaluating oral edaravone for Alzheimer's disease.
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CLINICAL_TRIALS trial_result · 2025-04-22Clinical Trial Update: Simufilam (PTI-125), 100 mg, for Mild-to-moderate Alzheimer's Disease Patients [Phase 2]
Phase 2 trial update for simufilam (PTI-125) at 100 mg is completed with results posted for patients with mild-to-moderate Alzheimer disease…
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CLINICAL_TRIALS trial_result · 2025-04-22Clinical Trial Update: Moving Together: An Online Group Movement Program for People Living With Memory Loss and Caregivers [NA]
A clinical trial evaluating an online group movement program for people living with memory loss and caregivers completed, with results poste…
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CLINICAL_TRIALS research · 2025-04-22Clinical Trial Update: A SMART Trial of Adaptive Exercises to Optimize Aerobic-Fitness Responses [NA]
The SMART Trial at Arizona State University is currently recruiting to evaluate adaptive exercises aimed at optimizing aerobic-fitness respo…