Alzheimer Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2008-01-04Clinical Trial Update: The Impact of Lorazepam on Cognition in APOE e4 Carriers [NA]
This completed Mayo Clinic trial examined whether lorazepam affects cognitive function in APOE e4 carriers with Alzheimer's disease.
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CLINICAL_TRIALS trial_result · 2007-12-28Clinical Trial Update: Study Evaluating the Effect of Lecozotan SR on the QTc Interval [Phase 1]
A Phase 1 clinical trial evaluating the effect of Lecozotan SR on the QTc interval in individuals with Alzheimer disease and healthy volunte…
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CLINICAL_TRIALS trial_result · 2007-12-21Clinical Trial Update: Study of the Effects of Current Drug Treatments on Levels of Certain Brain Chemicals in Alzheimer's Disease [Phase 4]
A Phase 4 clinical trial update from Novartis evaluating the effects of current Alzheimer's disease medications on brain chemical levels. Th…
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CLINICAL_TRIALS trial_result · 2007-12-21Clinical Trial Update: Safety and Tolerability of Rivastigmine With Add-on Memantine in Patients With Probable Alzheimer's Disease [Phase 4]
A Phase 4 trial assessed the safety and tolerability of rivastigmine with add-on memantine in patients with probable Alzheimer's disease; th…
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CLINICAL_TRIALS trial_result · 2007-12-11Clinical Trial Update: Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics of SAM-531 in Healthy Young and Elderly Subjects [Phase 1]
Phase 1 study evaluating the safety, pharmacokinetics, and pharmacodynamics of SAM-531 in healthy young and elderly subjects; Alzheimer’s di…
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CLINICAL_TRIALS trial_result · 2007-12-10Clinical Trial Update: Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SAM-531 in Healthy Subjects [Phase 1]
Phase 1 study evaluating SAM-531 in healthy subjects to assess safety, tolerability, pharmacokinetics, and pharmacodynamics; the Alzheimer's…
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CLINICAL_TRIALS research · 2007-12-10Clinical Trial Update: European Study of 3APS in Mild to Moderate Alzheimer's Disease Patients [Phase 3]
An update on a Phase 3 European study of 3APS for mild-to-moderate Alzheimer's disease; the document does not provide trial results.
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CLINICAL_TRIALS trial_result · 2007-12-05Clinical Trial Update: Study Comparing Lecozotan SR Two 5-mg Tablets Vs. Lecozotan SR One 10-mg Tablet in Healthy Subjects [Phase 1]
Phase 1 study comparing two 5 mg Lecozotan SR tablets versus one 10 mg Lecozotan SR tablet to evaluate pharmacokinetics in healthy subjects.…
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CLINICAL_TRIALS trial_result · 2007-12-05Clinical Trial Update: Single Ascending Dose Study of SRA-444 in Healthy Subjects [Phase 1]
This document reports the completion of a Phase 1 single ascending dose study of SRA-444 in healthy subjects. The sponsor Wyeth is now a who…
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CLINICAL_TRIALS trial_result · 2007-12-05Clinical Trial Update: Study Evaluating the Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of SAM-315 in Healthy Adults [Phase 1]
Phase 1 study evaluating safety, tolerability, pharmacokinetics, and pharmacodynamics of SAM-315 in healthy adults. Alzheimer disease is lis…
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CLINICAL_TRIALS trial_result · 2007-12-05Clinical Trial Update: Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SAM-315 in Healthy Japanese Males [Phase 1]
Phase 1 study evaluating SAM-315 in healthy Japanese male volunteers has completed, assessing safety, tolerability, pharmacokinetics, and ph…
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CLINICAL_TRIALS trial_result · 2007-12-04Clinical Trial Update: The Effect of Anticholinesterase Drugs on Sleep in Alzheimer's Disease Patients [Phase 4]
Phase 4 trial updating the effect of anticholinesterase drugs on sleep in Alzheimer's disease patients, including those with obstructive sle…
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CLINICAL_TRIALS trial_result · 2007-11-06Clinical Trial Update: Adding Atomoxetine To Standard Medication Treatment In Patients With Alzheimer's Disease [Phase 2, Phase 3]
A completed Phase 2/3 trial evaluated adding atomoxetine to standard treatment in patients with Alzheimer's disease.
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FDA approval · 2007-10-31FDA Approved: RIVASTIGMINE TARTRATE — Original Application (Dr. Reddy's Laboratories Limited)
FDA approved Dr. Reddy's Laboratories' rivastigmine tartrate as an original-application generic (ANDA) product. It is indicated for the trea…
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CLINICAL_TRIALS trial_result · 2007-10-25Clinical Trial Update: Dopaminergic Enhancement of Learning and Memory in Healthy Adults and Patients With Dementia/Mild Cognitive Impairment [Phase 4]
Phase 4 clinical trial update evaluating dopaminergic enhancement of learning and memory in healthy adults and individuals with Alzheimer's …
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FDA approval · 2007-10-22FDA Approved: RIVASTIGMINE TARTRATE — Original Application (Sun Pharmaceutical Industries, Inc.)
FDA approved a generic rivastigmine tartrate product from Sun Pharmaceutical Industries under an original ANDA, for the same indications as …
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CLINICAL_TRIALS research · 2007-10-12Clinical Trial Update: PET Study of the Nicotinic Receptors in Human
This clinical trial evaluating nicotinic receptor PET imaging in humans was terminated; it enrolled healthy individuals and patients with Pa…
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CLINICAL_TRIALS research · 2007-09-27Clinical Trial Update: The Serotonergic Transmitter System in Dementia and Affective Disorders
Clinical trial update on exploring the serotonergic transmitter system in dementia and affective disorders, sponsored by Rigshospitalet (Den…
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CLINICAL_TRIALS trial_result · 2007-09-20Clinical Trial Update: ALADDIN Study - Phase III: Antigonadotropin-Leuprolide in Alzheimer's Disease Drug INvestigation (VP-AD-301) [Phase 3]
The ALADDIN Phase III study VP-AD-301 evaluating leuprolide for Alzheimer's disease has completed.
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CLINICAL_TRIALS research · 2007-09-20Clinical Trial Update: Couples Coping With Alzheimer's Disease [NA]
This is a clinical trial update about couples coping with Alzheimer's disease. The current status is unknown and phase information is not ap…
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CLINICAL_TRIALS trial_result · 2007-09-18Clinical Trial Update: Healthy Aging and Memory Study
The Healthy Aging and Memory Study focusing on Alzheimer’s disease has completed.
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CLINICAL_TRIALS trial_result · 2007-08-31Clinical Trial Update: Diffusion Tensor Weighted MRI in Alzheimer's Disease Modifying Treatment Effects of Galantamine (Reminyl®) [Phase 4]
Phase 4 clinical trial evaluating galantamine (Reminyl) for Alzheimer's disease using diffusion tensor MRI to assess treatment effects.
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CLINICAL_TRIALS trial_result · 2007-07-16Clinical Trial Update: Open-Label Extension of the Phase III Study With Tramiprosate (3APS) in Patients With Mild to Moderate Alzheimer's Disease [Phase 3]
Open-label extension update of a Phase III study evaluating tramiprosate (3APS) in patients with mild to moderate Alzheimer's disease.
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FDA approval · 2007-07-06FDA Approved: RIVASTIGMINE — Original Application (Sandoz Inc)
FDA approved rivastigmine under an original application from Sandoz Inc, marking the approval of a rivastigmine generic product.
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CLINICAL_TRIALS trial_result · 2007-05-28Clinical Trial Update: Effects of LY450139 Dihydrate on Subjects With Mild to Moderate Alzheimer's Disease [Phase 2]
This document reports the completion of a Phase 2 trial evaluating LY450139 dihydrate (semagacestat) in individuals with mild to moderate Al…