Alzheimer Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2010-06-02Clinical Trial Update: Solanezumab Safety Study in Japanese Patients With Alzheimer's Disease [Phase 2]
Phase 2 safety study of solanezumab in Japanese patients with Alzheimer's disease has completed, focusing on safety and tolerability in this…
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CLINICAL_TRIALS trial_result · 2010-05-27Clinical Trial Update: Long-term Safety and Tolerability of AFFITOPE AD01
This clinical trial update reports long-term safety and tolerability data for AFFITOPE AD01 in Alzheimer's disease; the study has completed.
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CLINICAL_TRIALS trial_result · 2010-05-27Clinical Trial Update: Long-term Safety and Tolerability of AFFITOPE AD02
A long-term safety and tolerability update of the Alzheimer's disease vaccine candidate AFFITOPE AD02 from Affiris AG has been completed.
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CLINICAL_TRIALS trial_result · 2010-05-19Clinical Trial Update: Exelon Patch and Combination With Memantine Comparative Trial [Phase 4]
Phase 4 comparative trial evaluating rivastigmine transdermal patch alone versus in combination with memantine for Alzheimer's disease has c…
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FDA approval · 2010-05-05FDA Approved: MEMANTINE HYDROCHLORIDE — Original Application (Sun Pharmaceutical Industries, Inc.)
The FDA approved Sun Pharmaceutical's memantine hydrochloride generic under an original application.
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CLINICAL_TRIALS trial_result · 2010-04-28Clinical Trial Update: Safety and Efficacy of High Dose, Rapid Titration Galantamine in Patients With Alzheimer's Disease [Phase 3]
Phase 3 trial update evaluating the safety and efficacy of high-dose, rapid-titration galantamine in Alzheimer's disease; the study has been…
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FDA approval · 2010-04-14FDA Approved: MEMANTINE — Original Application (NorthStar RxLLC)
The FDA approved the original application for memantine as a generic product, manufactured by NorthStar RxLLC. This marks the availability o…
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CLINICAL_TRIALS trial_result · 2010-04-13Clinical Trial Update: Do HMG CoA Reductase Inhibitors Affect Abeta Levels? [Phase 4]
Phase 4 trial evaluated whether HMG-CoA reductase inhibitors affect Abeta levels in Alzheimer's disease. The study status is completed.
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CLINICAL_TRIALS trial_result · 2010-04-02Clinical Trial Update: Study GSI-136 in Healthy Young and Healthy Elderly Subjects [Phase 1]
Phase 1 study of GSI-136 in healthy young and elderly subjects has completed; Wyeth (Pfizer) sponsored the trial, which lists Alzheimer's di…
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CLINICAL_TRIALS trial_result · 2010-03-16Clinical Trial Update: Project COPE:Managing Dementia at Home [Phase 3]
Phase 3 clinical trial update for Project COPE: Managing Dementia at Home, investigating at-home management for Alzheimer's-type dementia. T…
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CLINICAL_TRIALS trial_result · 2010-02-26Clinical Trial Update: Fish Oil and Alpha Lipoic Acid in Treating Alzheimer's Disease [Phase 1, Phase 2]
Phase 1/2 clinical trial update evaluating fish oil and alpha-lipoic acid for Alzheimer's disease; results were posted in 2010.
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CLINICAL_TRIALS trial_result · 2010-02-23Clinical Trial Update: LifeZig Personalized Reminiscence Video With Slideshows and Music for Individuals With Alzheimer's and Dementia [Phase 2]
ClinicalTrials.gov update reports the results of a Phase 2 trial evaluating LifeZig, a personalized reminiscence video with slideshows and m…
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CLINICAL_TRIALS trial_result · 2010-02-08Clinical Trial Update: Study Evaluating The Potential Interaction Between Verapamil Immediate Release And SAM-531 When Co-Administered [Phase 1]
Phase 1 trial evaluating the potential interaction between Verapamil Immediate Release and SAM-531 when co-administered in Alzheimer disease…
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CLINICAL_TRIALS trial_result · 2010-02-03Clinical Trial Update: A Study Evaluating The Absorption Of Dimebon Into The Body From A Dimebon Solution Applied To The Skin [Phase 1]
Phase 1 study evaluating systemic absorption of dimebon when applied as a skin solution in participants with Alzheimer's disease or Huntingt…
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CLINICAL_TRIALS trial_result · 2010-01-29Clinical Trial Update: A Multi-Center, Randomized, Double-Blind, Parallel Group Study With 3 Groups Receiving Placebo, 5 mg of E2020 and 10 mg of E2020 [Phase 2]
A multi-center, randomized, double-blind Phase 2 trial comparing placebo, 5 mg, and 10 mg of E2020 (donepezil) in Alzheimer's disease has co…
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CLINICAL_TRIALS research · 2010-01-25Clinical Trial Update: Disease-modifying Properties of Lithium in the Neurobiology of Alzheimer's Disease [Phase 2]
A Phase 2 clinical trial is investigating whether lithium has disease-modifying effects in Alzheimer's disease.
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CLINICAL_TRIALS trial_result · 2010-01-12Clinical Trial Update: A Study In Healthy Volunteers To Estimate The Pharmacokinetics Of Four Modified-Release Formulations Of Dimebon (Latrepirdine) [Phase 1]
Pfizer conducted a Phase 1 pharmacokinetic study in healthy volunteers to compare four modified-release formulations of dimebon (latrepirdin…
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CLINICAL_TRIALS research · 2009-12-30Clinical Trial Update: A Phase 1, Non-Randomized, Open-Label, Single-Dose Study To Evaluate The Pharmacokinetics, Safety, And Tolerability Of Dimebon [PF 01913539] In Subjects With Severely-Impaired And Normal Renal Function [Phase 1]
A Phase 1, non-randomized, open-label pharmacokinetics and safety study of Dimebon (latrepirdine) in subjects with severely impaired and nor…
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CLINICAL_TRIALS research · 2009-12-29Clinical Trial Update: Amyloid Plaque and Tangle Imaging in Alzheimer's Disease and Down Syndrome
The National Institute on Aging reports an imaging-focused clinical trial studying amyloid plaques and tau tangles in Alzheimer's disease an…
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CLINICAL_TRIALS research · 2009-12-29Clinical Trial Update: Glucose Metabolic, Amyloid, and Tau Brain Imaging in Down Syndrome and Dementia
This entry notes an ongoing clinical trial from the National Institute on Aging evaluating glucose metabolism, amyloid, and tau brain imagin…
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CLINICAL_TRIALS trial_result · 2009-12-29Clinical Trial Update: Memory Aid for Informed Consent in Alzheimer's Research [NA]
This update describes a National Institute on Aging–sponsored trial evaluating a memory aid to improve informed consent in Alzheimer's disea…
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CLINICAL_TRIALS research · 2009-12-29Clinical Trial Update: Implications of Amyloid Pathology
Clinical trial update from the National Institute on Aging discusses the implications of amyloid pathology for Alzheimer's disease.
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CLINICAL_TRIALS trial_result · 2009-12-24Clinical Trial Update: A Dose Ranging Study To Investigate The Efficacy And Safety Of SB-742457 In Alzheimer's Disease [Phase 2]
A Phase 2 dose-ranging study evaluating the efficacy and safety of SB-742457 (idalopirdine) in Alzheimer's disease has completed.
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CLINICAL_TRIALS research · 2009-12-14Clinical Trial Update: Predictors of Cognitive Decline in Normal Aging
A National Institute on Aging–sponsored clinical trial investigates predictors of cognitive decline in normal aging. The study references co…
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CLINICAL_TRIALS trial_result · 2009-12-11Clinical Trial Update: The Safety and Efficacy of an Investigational Drug in Delaying the Progression of Alzheimer's Disease [Phase 3]
A Phase 3 trial evaluating the safety and efficacy of an investigational Alzheimer's disease drug sponsored by Merck was terminated; no effi…