Alzheimer Disease

• CLINICAL_TRIALS trial_result · 2011-09-13
  Clinical Trial Update: Memantine and Antipsychotics Use [Phase 4]

  A Phase 4 trial evaluating memantine use with antipsychotics for Alzheimer's disease was terminated, with results posted on 2011-09-13.

• CLINICAL_TRIALS trial_result · 2011-09-13
  Clinical Trial Update: Deep Transcranial Magnetic Stimulation in Patients With Alzheimer's Disease [Phase 2]

  Phase 2 study evaluating deep transcranial magnetic stimulation in Alzheimer's disease; the trial status is unknown.

• CLINICAL_TRIALS trial_result · 2011-09-07
  Clinical Trial Update: Early Detection of Mild Cognitive Impairment in Individual Patients

  This clinical trial update reports on a completed study evaluating early detection of mild cognitive impairment and Alzheimer's disease in i…

• CLINICAL_TRIALS safety_alert · 2011-09-02
  Clinical Trial Update: A Study of the Long-term Safety of ABT-089 for Subjects With Mild-to-moderate Alzheimer's Disease Who Participated in the M06-876 Study [Phase 2]

  A Phase 2 study evaluating the long-term safety of ABT-089 in patients with mild-to-moderate Alzheimer's disease who participated in the M06…

• CLINICAL_TRIALS trial_result · 2011-08-23
  Clinical Trial Update: Study to Evaluate Safety, Tolerability and Immunogenicity of Vaccine (UB 311) in Subjects With Alzheimer's Disease [Phase 1]

  Phase 1 trial update evaluating the safety, tolerability, and immunogenicity of the UB 311 vaccine in Alzheimer's disease patients has been …

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• CLINICAL_TRIALS trial_result · 2011-08-23
  Clinical Trial Update: Safety and Efficacy Study of ABT-089 in Adults With Mild to Moderate Alzheimer's Disease [Phase 2]

  A Phase 2 safety and efficacy trial of ABT-089 in adults with mild to moderate Alzheimer's disease was terminated.

• CLINICAL_TRIALS trial_result · 2011-08-18
  Clinical Trial Update: Telephone Call From Acute Care Physicians to Long Term Care Physicians: Impact on Transitional Care of Elderly Patients [Phase 1]

  Phase 1 clinical trial update examining whether structured telephone communication between acute care and long-term care physicians improves…

• CLINICAL_TRIALS trial_result · 2011-08-12
  Clinical Trial Update: Multiple Intravenous Dose Study Of PF-04360365 In Japanese Patients With Mild To Moderate Alzheimer's Disease [Phase 1]

  A Phase 1 multiple-dose intravenous study of PF-04360365 in Japanese patients with mild to moderate Alzheimer's disease has completed.

• CLINICAL_TRIALS research · 2011-07-27
  Clinical Trial Update: Innovative Biomarkers in Alzheimer's Disease and Frontotemporal Dementia (FTD): Preventative and Personalized

  This clinical trial update discusses innovative biomarkers for Alzheimer's disease and frontotemporal dementia to support preventative and p…

• CLINICAL_TRIALS trial_result · 2011-07-26
  Clinical Trial Update: A 24 Week, Multicenter, Open, Evaluation of the Clinical Effectiveness of the Once-daily 10 cm^2 Rivastigmine Patch Formulation in Patients With Probable Alzheimer's Disease (EXTRA) [Phase 4]

  This ClinicalTrials.gov entry reports a Phase 4, multicenter, open-label evaluation of the clinical effectiveness of the once-daily rivastig…

• CLINICAL_TRIALS trial_result · 2011-07-25
  Clinical Trial Update: Safety and Efficacy of Positron Emission Tomography (PET) Imaging With MNI-558 [EARLY_Phase 1]

  This early-phase study reports initial safety and imaging efficacy data for the PET radioligand MNI-558 in Alzheimer's disease.

• CLINICAL_TRIALS trial_result · 2011-07-22
  Clinical Trial Update: Efficacy and Safety of Tamibarotene (OAM80) for Alzheimer's Disease [Phase 2]

  Phase 2 study evaluating the efficacy and safety of Tamibarotene (OAM80) for Alzheimer's disease; this update summarizes the ongoing results…

• CLINICAL_TRIALS trial_result · 2011-07-14
  Clinical Trial Update: Safety, Tolerability, and Pharmacokinetic Study of EVP-6124 in Patients With Alzheimer's Disease [Phase 1]

  Phase 1 safety, tolerability, and pharmacokinetic study of EVP-6124 in Alzheimer's disease completed; results posted in 2011.

• CLINICAL_TRIALS trial_result · 2011-07-13
  Clinical Trial Update: Observational Study to Monitor Long-term Immunogenicity and Efficacy of UB 311 Vaccine in Subjects With Alzheimer's Disease

  A completed observational study assessing long-term immunogenicity and potential efficacy of the UB-311 vaccine in individuals with Alzheime…

• CLINICAL_TRIALS trial_result · 2011-07-08
  Clinical Trial Update: Safety and Efficacy Study of Magnetic Fields to Treat Alzheimer's Disease [NA]

  This document provides an update on a clinical trial evaluating the safety and efficacy of magnetic fields for the treatment of Alzheimer's …

• CLINICAL_TRIALS trial_result · 2011-06-27
  Clinical Trial Update: Safety of Switching From Donepezil to Rivastigmine Patch in Patients With Probable Alzheimer's Disease [Phase 3]

  Phase 3 trial evaluating the safety of switching from donepezil to rivastigmine patch in patients with probable Alzheimer's disease; results…

• CLINICAL_TRIALS research · 2011-06-22
  Clinical Trial Update: Study of the Role of G72 in Amyotrophic Lateral Sclerosis: Biomarker Discovery and Mechanism Investigation

  A clinical trial investigating the role of the G72 gene in amyotrophic lateral sclerosis, focusing on biomarker discovery and mechanism inve…

• CLINICAL_TRIALS trial_result · 2011-06-21
  Clinical Trial Update: Treatment of Severe Alzheimer's Disease: Evaluation of Efficacy and Safety of Galantamine Hydrobromide in a Controlled Study [Phase 3]

  A Phase 3 clinical trial evaluating the efficacy and safety of galantamine hydrobromide for severe Alzheimer's disease has completed.

• CLINICAL_TRIALS trial_result · 2011-06-13
  Clinical Trial Update: An Efficacy and Safety Study of INM-176 for the Treatment of Patients With Alzheimer Type Dementia [Phase 3]

  Phase 3 clinical trial evaluating the efficacy and safety of INM-176 for Alzheimer's disease has completed.

• CLINICAL_TRIALS trial_result · 2011-06-08
  Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Galantamine in Patients With Mild Cognitive Impairment [Phase 3]

  This Phase 3 trial update reports the completion of a study evaluating the efficacy and safety of Galantamine in patients with Mild Cognitiv…

• CLINICAL_TRIALS trial_result · 2011-06-08
  Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Galantamine in Patients With Mild Cognitive Impairment [Phase 3]

  Phase 3 trial evaluating the efficacy and safety of galantamine in patients with mild cognitive impairment has completed.

• CLINICAL_TRIALS trial_result · 2011-06-08
  Clinical Trial Update: A Study of the Effects on Sleep, Attention, and Gastrointestinal Tolerance of Galantamine and Donepezil in Patients With Alzheimer's Disease [Phase 4]

  A completed Phase 4 study comparing galantamine and donepezil in Alzheimer's disease, assessing effects on sleep, attention, and gastrointes…

• CLINICAL_TRIALS trial_result · 2011-06-03
  Clinical Trial Update: A Clinical Study Evaluating the Effects of Memantine on Brain Atrophy in Patients With Alzheimer's Disease [Phase 4]

  Phase 4 clinical trial evaluating memantine's effect on brain atrophy in Alzheimer's disease has completed, with results posted in 2011.

• CLINICAL_TRIALS trial_result · 2011-06-01
  Clinical Trial Update: Non Pharmacological Treatment in Alzheimer's Disease and Associated Disorders [NA]

  A non-pharmacological treatment study for Alzheimer's disease and associated disorders sponsored by Centre Hospitalier Universitaire de Nice…

• FDA approval · 2011-05-31
  FDA Approved: DONEPEZIL HYDROCHLORIDE — Original Application (ACI Healthcare USA, Inc.)

  FDA approved a generic donepezil hydrochloride product under an original application, intended for the treatment of Alzheimer's disease.